SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 1gn1 CCT-GAMMA
(Mus
musculus) 		5 / 12 ILE A 282
LEU A 304
ILE A 296
ALA A 300
PRO A 335
 None
 1.00A 3vrmA-1gn1A:
0.0		 3vrmA-1gn1A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1gn1 CCT-GAMMA
(Mus
musculus) 		3 / 3 VAL A 343
THR A 345
ARG A 237
 None
 0.59A 5b2sB-1gn1A:
0.3		 5b2sB-1gn1A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1gn1 CCT-GAMMA
(Mus
musculus) 		3 / 3 VAL A 343
THR A 345
ARG A 237
 None
 0.57A 5b2tB-1gn1A:
0.0		 5b2tB-1gn1A:
9.19