SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gn4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		3 / 3 VAL A  74
TRP A  79
TRP A  80
 None
 1.23A 2xdcC-1gn4A:
undetectable
2xdcD-1gn4A:
undetectable		 2xdcC-1gn4A:
5.52
2xdcD-1gn4A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		3 / 3 TRP A  80
VAL A  74
TRP A  79
 None
 0.44A 2xdcC-1gn4A:
undetectable
2xdcD-1gn4A:
undetectable		 2xdcC-1gn4A:
5.52
2xdcD-1gn4A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		3 / 3 TRP A  80
VAL A  74
TRP A  79
 None
 0.39A 2xdcE-1gn4A:
undetectable
2xdcF-1gn4A:
undetectable		 2xdcE-1gn4A:
5.52
2xdcF-1gn4A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		3 / 3 TRP A  80
VAL A  74
TRP A  79
 None
 0.43A 2y5mE-1gn4A:
undetectable
2y5mF-1gn4A:
undetectable		 2y5mE-1gn4A:
5.52
2y5mF-1gn4A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		3 / 3 TRP A  80
VAL A  74
TRP A  79
 None
 0.39A 2y6nC-1gn4A:
undetectable
2y6nD-1gn4A:
undetectable		 2y6nC-1gn4A:
5.52
2y6nD-1gn4A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		3 / 3 TRP A  80
VAL A  74
TRP A  79
 None
 0.41A 2y6nE-1gn4A:
undetectable
2y6nF-1gn4A:
undetectable		 2y6nE-1gn4A:
5.52
2y6nF-1gn4A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		4 / 7 ALA A  97
ALA A  98
ALA A 100
GLN A 191
 None
 0.74A 3a2qA-1gn4A:
0.0		 3a2qA-1gn4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		3 / 3 VAL A  74
TRP A  79
TRP A  80
 None
 1.15A 3zq8A-1gn4A:
undetectable
3zq8B-1gn4A:
undetectable		 3zq8A-1gn4A:
5.52
3zq8B-1gn4A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		3 / 3 TRP A  80
VAL A  74
TRP A  79
 None
 0.91A 3zq8A-1gn4A:
undetectable
3zq8B-1gn4A:
undetectable		 3zq8A-1gn4A:
5.52
3zq8B-1gn4A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		4 / 6 TYR A   4
VAL A  44
ASP A  42
ALA A  43
 None
 0.90A 5cu6A-1gn4A:
undetectable		 5cu6A-1gn4A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1gn4 SUPEROXIDE DISMUTASE
(Mycobacterium
tuberculosis) 		4 / 5 TYR A   4
VAL A  44
ASP A  42
ALA A  43
 None
 0.86A 5otrA-1gn4A:
undetectable		 5otrA-1gn4A:
20.70