SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gny'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1gny XYLANASE 10C
(Cellvibrio
japonicus) 		5 / 9 GLY A 219
GLN A 217
ILE A 232
VAL A 235
VAL A  97
 None
XYP  A1246 (-3.2A)
None
None
None
 1.40A 3fi0K-1gnyA:
undetectable		 3fi0K-1gnyA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1gny XYLANASE 10C
(Cellvibrio
japonicus) 		5 / 9 GLY A 219
GLN A 217
ILE A 232
VAL A 235
VAL A  97
 None
XYP  A1246 (-3.2A)
None
None
None
 1.37A 3fi0O-1gnyA:
undetectable		 3fi0O-1gnyA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1gny XYLANASE 10C
(Cellvibrio
japonicus) 		5 / 12 ALA A 240
ASN A  92
ASP A 205
ASP A 207
ASP A 146
 None
 1.23A 3wemA-1gnyA:
undetectable		 3wemA-1gnyA:
9.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1gny XYLANASE 10C
(Cellvibrio
japonicus) 		5 / 12 ALA A 240
ASN A  92
ASP A 205
ASP A 207
ASP A 146
 None
 1.24A 3wenA-1gnyA:
undetectable		 3wenA-1gnyA:
9.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1gny XYLANASE 10C
(Cellvibrio
japonicus) 		5 / 12 ALA A 240
ASN A  92
ASP A 205
ASP A 207
ASP A 146
 None
 1.19A 3weoA-1gnyA:
undetectable		 3weoA-1gnyA:
9.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1gny XYLANASE 10C
(Cellvibrio
japonicus) 		5 / 12 VAL A 153
ILE A 237
GLY A 219
ILE A 232
LEU A 166
 None
 1.03A 4mwzB-1gnyA:
undetectable		 4mwzB-1gnyA:
20.60