SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1go3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT F
(Methanocaldococc
us
jannaschii) 		4 / 8 SER F  15
LEU F  47
LEU F  76
ASP F  74
 None
 0.97A 2j2pA-1go3F:
undetectable
2j2pB-1go3F:
undetectable		 2j2pA-1go3F:
20.19
2j2pB-1go3F:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE E 176
LEU E 173
MET E 165
THR E 164
 None
 1.08A 2zxwN-1go3E:
0.0
2zxwW-1go3E:
0.0		 2zxwN-1go3E:
14.98
2zxwW-1go3E:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE E 176
LEU E 173
MET E 165
THR E 164
 None
 1.04A 3ablA-1go3E:
undetectable
3ablJ-1go3E:
0.0		 3ablA-1go3E:
14.98
3ablJ-1go3E:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE E 176
LEU E 173
MET E 165
THR E 164
 None
 1.04A 3ag4N-1go3E:
undetectable
3ag4W-1go3E:
0.0		 3ag4N-1go3E:
14.98
3ag4W-1go3E:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
DNA-DIRECTED RNA
POLYMERASE SUBUNIT F
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU E  30
VAL E  49
ILE E   4
LEU F   7
VAL E  51
 None
 0.98A 3em6B-1go3E:
undetectable		 3em6B-1go3E:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE E 138
ASP E  91
GLY E 102
ILE E 146
ILE E 161
 None
 1.09A 3pwwA-1go3E:
undetectable		 3pwwA-1go3E:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
(Methanocaldococc
us
jannaschii) 		4 / 6 GLU E  86
LEU E 173
TYR E 141
GLU E  88
 None
 1.11A 3w9tB-1go3E:
undetectable		 3w9tB-1go3E:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
(Methanocaldococc
us
jannaschii) 		4 / 6 GLU E  86
LEU E 173
TYR E 141
GLU E  88
 None
 1.11A 3w9tE-1go3E:
undetectable		 3w9tE-1go3E:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
(Methanocaldococc
us
jannaschii) 		4 / 6 GLU E  86
LEU E 173
TYR E 141
GLU E  88
 None
 1.11A 3w9tF-1go3E:
undetectable		 3w9tF-1go3E:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
(Methanocaldococc
us
jannaschii) 		4 / 6 ILE E 176
LEU E 173
MET E 165
THR E 164
 None
 1.05A 3wg7A-1go3E:
undetectable
3wg7J-1go3E:
0.0		 3wg7A-1go3E:
14.98
3wg7J-1go3E:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
DNA-DIRECTED RNA
POLYMERASE SUBUNIT F
(Methanocaldococc
us
jannaschii) 		5 / 9 LEU F  41
LEU F  59
ILE F  72
TYR E   2
MET E   1
 None
 1.20A 3zosB-1go3F:
undetectable		 3zosB-1go3F:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT F
(Methanocaldococc
us
jannaschii) 		5 / 9 THR F  68
LEU F  59
PRO F  77
ILE F  99
LEU F  62
 None
 1.16A 5g48B-1go3F:
undetectable		 5g48B-1go3F:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
DNA-DIRECTED RNA
POLYMERASE SUBUNIT F
(Methanocaldococc
us
jannaschii) 		3 / 3 VAL F  14
GLU E  80
GLU E  83
 None
 0.94A 5jsdB-1go3F:
undetectable
5jsdC-1go3F:
undetectable		 5jsdB-1go3F:
9.84
5jsdC-1go3F:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
DNA-DIRECTED RNA
POLYMERASE SUBUNIT F
(Methanocaldococc
us
jannaschii;
Methanocaldococc
us
jannaschii) 		5 / 12 LEU E  46
VAL E  49
GLU F  16
ALA F  45
ALA F  18
 None
 1.00A 5n5dB-1go3E:
undetectable		 5n5dB-1go3E:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1go3 DNA-DIRECTED RNA
POLYMERASE SUBUNIT E
(Methanocaldococc
us
jannaschii) 		4 / 6 ILE E 176
LEU E 173
MET E 165
THR E 164
 None
 1.03A 6nmfN-1go3E:
undetectable
6nmfW-1go3E:
0.0		 6nmfN-1go3E:
14.98
6nmfW-1go3E:
15.06