SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1goj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 12 ILE A  76
LEU A 233
GLY A  79
GLY A 229
ASN A 298
 None
 1.05A 1likA-1gojA:
undetectable		 1likA-1gojA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 12 ILE A 305
THR A  97
ILE A  64
ILE A 304
THR A 317
 None
 1.01A 1re7A-1gojA:
undetectable		 1re7A-1gojA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		4 / 8 SER A 308
ARG A  15
PHE A  14
ASN A 313
 None
 1.24A 1rs7B-1gojA:
0.0		 1rs7B-1gojA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		4 / 7 TYR A 282
THR A  83
THR A 301
VAL A 268
 None
 1.23A 1tv8A-1gojA:
undetectable		 1tv8A-1gojA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 12 GLY A 297
GLY A 296
VAL A 268
SER A 278
LEU A 272
 None
 1.04A 1ya4C-1gojA:
undetectable		 1ya4C-1gojA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		4 / 8 SER A 308
ARG A  15
PHE A  14
ASN A 313
 None
 1.33A 1zzqB-1gojA:
0.0		 1zzqB-1gojA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		4 / 8 SER A 308
ARG A  15
PHE A  14
ASN A 313
 None
 1.31A 1zzuB-1gojA:
0.0		 1zzuB-1gojA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 8 LEU A 172
ASP A 148
ALA A 151
ILE A 175
GLY A 190
 None
 1.35A 2o4nB-1gojA:
undetectable		 2o4nB-1gojA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 8 GLY A  93
ASN A 306
ILE A  69
VAL A  10
SER A  95
 ADP  A 400 (-3.1A)
None
None
None
MG  A 401 ( 2.1A)
 1.30A 2yoeB-1gojA:
0.0
2yoeC-1gojA:
0.0		 2yoeB-1gojA:
22.37
2yoeC-1gojA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		4 / 6 TYR A 132
ILE A 216
SER A 125
SER A 126
 None
 0.95A 3pmzD-1gojA:
0.0		 3pmzD-1gojA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		4 / 8 GLY A  88
ILE A 305
THR A 317
THR A 320
 None
 0.86A 4em2A-1gojA:
undetectable		 4em2A-1gojA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 12 GLY A  88
ALA A  92
PHE A  14
VAL A  40
GLN A  89
 None
ADP  A 400 (-4.3A)
None
None
None
 1.47A 4ryaA-1gojA:
0.0		 4ryaA-1gojA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 12 ILE A 305
THR A  97
ILE A  64
ILE A 304
THR A 317
 None
 0.93A 4x5iA-1gojA:
undetectable		 4x5iA-1gojA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 12 ILE A 305
THR A  97
ILE A  64
ILE A 304
THR A 317
 None
 0.91A 4x5jA-1gojA:
undetectable		 4x5jA-1gojA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		3 / 3 THR A  72
HIS A 209
LEU A 291
 None
 0.76A 5axdA-1gojA:
undetectable		 5axdA-1gojA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		3 / 3 THR A  72
HIS A 209
LEU A 291
 None
 0.78A 5axdC-1gojA:
undetectable		 5axdC-1gojA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		4 / 7 VAL A 111
ILE A 115
VAL A  84
ILE A 304
 None
 0.75A 5bmvC-1gojA:
undetectable		 5bmvC-1gojA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 12 ILE A 305
THR A  97
ILE A  64
ILE A 304
THR A 317
 None
 0.93A 5eajA-1gojA:
undetectable		 5eajA-1gojA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 12 ILE A 330
PHE A 323
VAL A  54
GLY A 266
LEU A 236
 None
 1.40A 5esgA-1gojA:
undetectable		 5esgA-1gojA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 10 THR A 320
ILE A 305
LEU A 303
PHE A 323
ALA A  92
 None
None
None
None
ADP  A 400 (-4.3A)
 1.19A 5mxbA-1gojA:
0.0		 5mxbA-1gojA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 1goj KINESIN HEAVY CHAIN
(Neurospora
crassa) 		5 / 12 LEU A 236
LEU A 303
PHE A 323
ILE A 269
THR A 288
 None
 1.22A 6debB-1gojA:
undetectable		 6debB-1gojA:
12.18