SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gom'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 THR A  22
PRO A  45
THR A  44
 None
 0.94A 1dscC-1gomA:
undetectable		 1dscC-1gomA:
3.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 THR A  44
THR A  22
PRO A  45
 None
 0.79A 1dscC-1gomA:
undetectable		 1dscC-1gomA:
3.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		5 / 12 GLY A  19
ASP A   7
GLY A  77
ILE A  80
ILE A  36
 None
 0.87A 1hxbA-1gomA:
undetectable		 1hxbA-1gomA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.91A 1jnoA-1gomA:
undetectable		 1jnoA-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.91A 1jnoB-1gomA:
undetectable		 1jnoB-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.80A 1jo3A-1gomA:
undetectable		 1jo3A-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.80A 1jo3B-1gomA:
undetectable		 1jo3B-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.91A 1ng8A-1gomA:
undetectable		 1ng8A-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.90A 1ng8B-1gomA:
undetectable		 1ng8B-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.93A 1nruA-1gomA:
undetectable		 1nruA-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.93A 1nruB-1gomA:
undetectable		 1nruB-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.89A 1nt6A-1gomA:
undetectable		 1nt6A-1gomA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 ALA A 186
VAL A 191
TRP A 194
 None
 0.89A 1nt6B-1gomA:
undetectable		 1nt6B-1gomA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		4 / 6 ARG A 161
GLY A 203
THR A 230
ARG A 195
 None
 1.20A 2f7fA-1gomA:
4.3		 2f7fA-1gomA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		4 / 6 LEU A 139
VAL A 107
MET A 108
ILE A 148
 None
 1.13A 2hyyC-1gomA:
undetectable		 2hyyC-1gomA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		4 / 5 VAL A 251
TYR A 248
VAL A 240
ASP A 239
 None
 1.33A 2x45A-1gomA:
undetectable		 2x45A-1gomA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		4 / 5 VAL A 251
TYR A 248
VAL A 240
ASP A 239
 None
 1.31A 2x45C-1gomA:
undetectable		 2x45C-1gomA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 VAL A 240
TRP A 267
TRP A 275
 None
 1.38A 2y5mA-1gomA:
undetectable
2y5mB-1gomA:
undetectable		 2y5mA-1gomA:
4.03
2y5mB-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 VAL A 240
TRP A 267
TRP A 275
 None
 1.37A 2y6nA-1gomA:
undetectable
2y6nB-1gomA:
undetectable		 2y6nA-1gomA:
4.03
2y6nB-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 TRP A 275
VAL A 240
TRP A 267
 None
 1.38A 2y6nA-1gomA:
undetectable
2y6nB-1gomA:
undetectable		 2y6nA-1gomA:
4.03
2y6nB-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		4 / 7 ASP A 177
GLY A 205
VAL A 251
VAL A 218
 None
 0.81A 3ufnB-1gomA:
undetectable		 3ufnB-1gomA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		3 / 3 TRP A 275
VAL A 266
TRP A 267
 None
 1.19A 3zq8C-1gomA:
undetectable
3zq8D-1gomA:
undetectable		 3zq8C-1gomA:
4.03
3zq8D-1gomA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		4 / 6 GLU A  55
PHE A  61
HIS A  83
VAL A  70
 None
 1.09A 4a97I-1gomA:
undetectable		 4a97I-1gomA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		5 / 9 ALA A 254
ILE A 264
GLY A 263
THR A 208
VAL A 218
 None
 1.09A 4nptA-1gomA:
undetectable		 4nptA-1gomA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		4 / 8 VAL A 258
ILE A 204
ALA A 228
ARG A 124
 None
 0.81A 4qrcA-1gomA:
undetectable		 4qrcA-1gomA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		4 / 7 TYR A 181
PRO A 182
THR A 184
SER A 178
 None
 1.28A 5b6iA-1gomA:
undetectable		 5b6iA-1gomA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		5 / 12 VAL A 218
ASP A 177
ALA A 254
GLN A  42
GLY A 205
 None
 1.25A 5m54E-1gomA:
undetectable		 5m54E-1gomA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 1gom ENDO-1,4-BETA-XYLANA
SE
(Thermoascus
aurantiacus) 		6 / 12 GLY A  19
GLY A  41
LYS A  78
VAL A 266
ILE A  10
LEU A 283
 None
 1.32A 5wy0A-1gomA:
undetectable		 5wy0A-1gomA:
18.41