SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gp1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		3 / 3 ALA A 123
VAL A 113
TRP A 148
 None
 1.00A 1tkqA-1gp1A:
undetectable		 1tkqA-1gp1A:
4.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		4 / 5 LEU A  36
PRO A 171
VAL A 165
ILE A  38
 None
 0.99A 2aoiB-1gp1A:
undetectable		 2aoiB-1gp1A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		4 / 7 ARG A 178
GLU A 161
PRO A 132
ALA A 136
 None
 1.47A 2ejgB-1gp1A:
0.4		 2ejgB-1gp1A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		3 / 3 PHE A 105
ASN A  56
PHE A 101
 None
 0.99A 2zbuD-1gp1A:
undetectable		 2zbuD-1gp1A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		3 / 3 PRO A  73
SER A  43
ASN A  75
 None
 0.88A 3lslG-1gp1A:
0.0		 3lslG-1gp1A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		5 / 8 ARG A  61
GLY A  63
LEU A  67
LEU A  37
GLU A 189
 None
 1.38A 4po0A-1gp1A:
undetectable		 4po0A-1gp1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		5 / 10 GLY A  63
ASN A 104
ILE A 188
LEU A  62
LEU A  67
 None
 1.21A 4xj7A-1gp1A:
undetectable
4xj7B-1gp1A:
undetectable		 4xj7A-1gp1A:
23.67
4xj7B-1gp1A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		3 / 3 LEU A  67
ARG A  65
ARG A  61
 None
 0.97A 4yiaB-1gp1A:
0.0		 4yiaB-1gp1A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		3 / 3 ASN A  85
LEU A  92
PHE A 108
 None
 0.79A 5dsgA-1gp1A:
undetectable		 5dsgA-1gp1A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1gp1 GLUTATHIONE
PEROXIDASE
(Bos
taurus) 		3 / 3 GLU A 161
TRP A 158
ASN A 114
 None
SE7  A  45 ( 4.4A)
None
 1.00A 5dv4A-1gp1A:
undetectable		 5dv4A-1gp1A:
19.54