SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gpr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1gpr GLUCOSE PERMEASE
(Bacillus
subtilis) 		5 / 8 ASP A  28
ILE A  23
ILE A 144
GLY A  42
PRO A  18
 None
 1.40A 1sh9A-1gprA:
undetectable		 1sh9A-1gprA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1gpr GLUCOSE PERMEASE
(Bacillus
subtilis) 		5 / 11 ASN A  62
LEU A 113
VAL A  52
ILE A  60
THR A 129
 None
 1.31A 3fl9C-1gprA:
undetectable		 3fl9C-1gprA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 1gpr GLUCOSE PERMEASE
(Bacillus
subtilis) 		5 / 12 PRO A  18
GLN A 110
ARG A 105
LEU A 112
GLU A  13
 None
 1.07A 5mqtC-1gprA:
undetectable		 5mqtC-1gprA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1gpr GLUCOSE PERMEASE
(Bacillus
subtilis) 		4 / 7 LEU A  81
ALA A  69
ILE A  60
LEU A  72
 None
 0.95A 5te8C-1gprA:
undetectable		 5te8C-1gprA:
17.61