SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 12 VAL A 321
GLY A 320
TYR A 276
VAL A 206
PHE A 323
 None
 1.28A 1a27A-1gqjA:
undetectable		 1a27A-1gqjA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 4 ASP A 472
HIS A 473
ARG A 151
GLU A 430
 None
 1.36A 1lqtA-1gqjA:
3.2		 1lqtA-1gqjA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 PHE A 667
LEU A 519
LEU A 591
 None
 0.60A 1mx1E-1gqjA:
undetectable		 1mx1E-1gqjA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 7 ALA A 312
PHE A 245
ARG A 302
ASN A 309
 None
 1.32A 1t9wA-1gqjA:
0.0		 1t9wA-1gqjA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 8 TRP A 324
ALA A 326
LEU A 375
ASP A 303
 None
 1.02A 2bxkA-1gqjA:
2.3		 2bxkA-1gqjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 LEU A 538
ALA A 545
HIS A 528
ASP A 527
 None
None
XYP  A1719 (-4.4A)
None
 1.09A 2dpzA-1gqjA:
undetectable		 2dpzA-1gqjA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 12 ILE A  84
GLY A  90
ALA A 118
ALA A 117
VAL A 116
 None
 0.99A 2oc8A-1gqjA:
undetectable		 2oc8A-1gqjA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 LEU A 612
TYR A 616
GLY A 619
 None
 0.42A 2ocuA-1gqjA:
undetectable		 2ocuA-1gqjA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 LEU A 131
VAL A 114
ILE A  30
ILE A 135
 None
 0.89A 2piwA-1gqjA:
0.0		 2piwA-1gqjA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 TRP A 179
VAL A 166
TRP A 177
 None
CO  A1724 ( 4.3A)
None
 0.68A 2xdcC-1gqjA:
undetectable
2xdcD-1gqjA:
undetectable		 2xdcC-1gqjA:
2.66
2xdcD-1gqjA:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 TRP A 179
VAL A 166
TRP A 177
 None
CO  A1724 ( 4.3A)
None
 0.70A 2xdcE-1gqjA:
undetectable
2xdcF-1gqjA:
undetectable		 2xdcE-1gqjA:
2.66
2xdcF-1gqjA:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 TRP A 179
VAL A 166
TRP A 177
 None
CO  A1724 ( 4.3A)
None
 0.67A 2y5mE-1gqjA:
undetectable
2y5mF-1gqjA:
undetectable		 2y5mE-1gqjA:
2.66
2y5mF-1gqjA:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 TRP A 179
VAL A 166
TRP A 177
 None
CO  A1724 ( 4.3A)
None
 0.66A 2y6nC-1gqjA:
undetectable
2y6nD-1gqjA:
undetectable		 2y6nC-1gqjA:
2.66
2y6nD-1gqjA:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 TRP A 179
VAL A 166
TRP A 177
 None
CO  A1724 ( 4.3A)
None
 0.67A 2y6nE-1gqjA:
undetectable
2y6nF-1gqjA:
undetectable		 2y6nE-1gqjA:
2.66
2y6nF-1gqjA:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 MET A 503
SER A 461
PRO A 406
GLY A 405
 None
 1.45A 2y7pA-1gqjA:
0.0		 2y7pA-1gqjA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 9 ILE A 237
GLY A 236
TYR A 235
GLY A 201
PHE A 129
 None
None
None
EDO  A1713 ( 4.3A)
None
 1.41A 2y7wA-1gqjA:
0.1		 2y7wA-1gqjA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 5 VAL A 620
GLN A 627
PHE A 395
ARG A 660
 None
EDO  A1718 (-4.3A)
None
None
 1.45A 3bjwE-1gqjA:
0.0		 3bjwE-1gqjA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 9 VAL A 321
GLY A 284
ILE A 275
TYR A 276
GLY A 319
 None
 1.38A 3csjB-1gqjA:
undetectable		 3csjB-1gqjA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 4 ARG A 263
ASP A 258
ASP A 261
PRO A 262
 None
 1.30A 3fgrB-1gqjA:
0.0		 3fgrB-1gqjA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 GLY A 170
THR A 454
GLU A 168
GLU A 387
 None
 1.02A 3fpjA-1gqjA:
undetectable		 3fpjA-1gqjA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 ILE A 115
SER A 145
SER A 147
 None
 0.49A 3iltH-1gqjA:
1.1		 3iltH-1gqjA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 9 ILE A 207
LEU A 286
PHE A 323
ARG A 155
LEU A 200
 None
 1.46A 3nxuB-1gqjA:
undetectable		 3nxuB-1gqjA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 12 ILE A 135
VAL A 114
ALA A 117
TYR A 101
LEU A 102
 None
None
None
EDO  A1713 (-4.8A)
None
 1.21A 3ozuA-1gqjA:
undetectable		 3ozuA-1gqjA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 5 VAL A 156
GLU A 168
LYS A 288
PHE A 323
 None
 1.22A 3rv5C-1gqjA:
0.4
3rv5D-1gqjA:
0.4		 3rv5C-1gqjA:
8.26
3rv5D-1gqjA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 5 ARG A 165
TRP A 179
ILE A 207
ASN A 197
 None
 1.25A 4i00A-1gqjA:
undetectable		 4i00A-1gqjA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 LYS A 274
ARG A 271
TRP A 267
 None
 1.09A 4i90A-1gqjA:
4.9		 4i90A-1gqjA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 SER A 462
GLY A 448
ASP A 450
GLY A 170
 None
 1.01A 4koeA-1gqjA:
0.3
4koeB-1gqjA:
0.4
4koeC-1gqjA:
undetectable		 4koeA-1gqjA:
22.78
4koeB-1gqjA:
22.78
4koeC-1gqjA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 4 ASN A 361
GLY A 362
ASP A 290
ASP A 365
 None
None
None
XYP  A1719 (-3.3A)
 1.35A 4n49A-1gqjA:
undetectable		 4n49A-1gqjA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 8 HIS A 521
ASP A 365
SER A 291
PHE A 327
 XYP  A1719 (-4.1A)
XYP  A1719 (-3.3A)
None
None
 1.22A 4ndnA-1gqjA:
undetectable		 4ndnA-1gqjA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 7 HIS A 521
ASP A 365
SER A 291
PHE A 327
 XYP  A1719 (-4.1A)
XYP  A1719 (-3.3A)
None
None
 1.23A 4ndnC-1gqjA:
undetectable		 4ndnC-1gqjA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 12 LEU A 315
ILE A 243
VAL A 287
PHE A 344
ALA A 308
 None
 1.02A 4o1zB-1gqjA:
0.0		 4o1zB-1gqjA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 7 HIS A 521
ASP A 365
SER A 291
PHE A 327
 XYP  A1719 (-4.1A)
XYP  A1719 (-3.3A)
None
None
 1.25A 4odjA-1gqjA:
undetectable		 4odjA-1gqjA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 PRO A 539
LEU A 538
HIS A 528
 None
None
XYP  A1719 (-4.4A)
 0.69A 4pevA-1gqjA:
3.8		 4pevA-1gqjA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 ARG A 560
ASP A 335
TYR A 548
 None
 0.72A 4yo9B-1gqjA:
0.0		 4yo9B-1gqjA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 PHE A 221
LEU A 182
ASN A 184
PRO A 183
 None
 1.40A 4yv5B-1gqjA:
undetectable		 4yv5B-1gqjA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 PHE A 221
LEU A 182
ASN A 184
PRO A 183
 None
 1.42A 4yv5A-1gqjA:
0.0		 4yv5A-1gqjA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 GLY A 448
ASP A 450
GLY A 170
SER A 462
 None
 1.03A 4z53A-1gqjA:
1.6
4z53B-1gqjA:
0.0		 4z53A-1gqjA:
20.79
4z53B-1gqjA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 7 HIS A 521
ASP A 365
SER A 291
PHE A 327
 XYP  A1719 (-4.1A)
XYP  A1719 (-3.3A)
None
None
 1.26A 5a1iA-1gqjA:
undetectable		 5a1iA-1gqjA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 VAL A 444
VAL A 210
TRP A 160
PHE A 327
 None
 1.46A 5adeA-1gqjA:
0.0
5adeB-1gqjA:
0.0		 5adeA-1gqjA:
19.56
5adeB-1gqjA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 SER A 462
ARG A  13
GLY A   7
GLU A   5
 None
None
CO  A1722 (-3.5A)
None
 1.01A 5btaA-1gqjA:
0.3
5btaB-1gqjA:
undetectable
5btaC-1gqjA:
0.2		 5btaA-1gqjA:
21.79
5btaB-1gqjA:
17.58
5btaC-1gqjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 SER A 462
ARG A  13
GLY A   7
GLU A   5
 None
None
CO  A1722 (-3.5A)
None
 1.02A 5btcA-1gqjA:
0.3
5btcB-1gqjA:
undetectable
5btcC-1gqjA:
0.3		 5btcA-1gqjA:
21.79
5btcB-1gqjA:
17.58
5btcC-1gqjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 7 SER A 462
ARG A  13
GLY A   7
GLU A   5
 None
None
CO  A1722 (-3.5A)
None
 0.99A 5btfA-1gqjA:
0.2
5btfB-1gqjA:
undetectable
5btfC-1gqjA:
0.3		 5btfA-1gqjA:
21.79
5btfB-1gqjA:
17.58
5btfC-1gqjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 5 THR A 544
ALA A 545
THR A 535
HIS A 521
 None
None
None
XYP  A1719 (-4.1A)
 1.31A 5ecmA-1gqjA:
0.4		 5ecmA-1gqjA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 7 ILE A 237
GLY A 236
LEU A 315
PHE A 285
 None
 0.80A 5hieB-1gqjA:
undetectable		 5hieB-1gqjA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 HIS A 159
ASN A 446
ALA A 172
 None
 0.47A 5n4tB-1gqjA:
0.3		 5n4tB-1gqjA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 TYR A 126
SER A 199
TRP A 471
 None
None
EDO  A1713 ( 3.6A)
 0.97A 5n8jB-1gqjA:
undetectable		 5n8jB-1gqjA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 TYR A 126
SER A 199
TRP A 471
 None
None
EDO  A1713 ( 3.6A)
 0.92A 5n8jA-1gqjA:
0.0		 5n8jA-1gqjA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		3 / 3 TYR A 126
SER A 199
TRP A 471
 None
None
EDO  A1713 ( 3.6A)
 0.92A 5n8jD-1gqjA:
0.0		 5n8jD-1gqjA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 6 LEU A 103
VAL A 114
LEU A 134
GLU A  48
 None
 0.90A 5tudD-1gqjA:
2.2		 5tudD-1gqjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 9 ALA A 118
PHE A 129
GLY A 201
SER A 148
GLY A 100
 None
None
EDO  A1713 ( 4.3A)
EDO  A1715 (-3.5A)
None
 1.36A 6awoA-1gqjA:
1.7		 6awoA-1gqjA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 9 ALA A 118
PHE A 129
GLY A 201
SER A 148
GLY A 100
 None
None
EDO  A1713 ( 4.3A)
EDO  A1715 (-3.5A)
None
 1.37A 6awqA-1gqjA:
1.8		 6awqA-1gqjA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 8 LEU A 125
TYR A 126
GLU A  99
THR A  41
 None
 1.07A 6c71B-1gqjA:
undetectable		 6c71B-1gqjA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		5 / 12 GLY A 557
HIS A 549
TYR A 547
ARG A 560
GLY A 518
 None
 1.25A 6gngA-1gqjA:
2.4		 6gngA-1gqjA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 8 ASP A 542
ILE A 333
ARG A 336
ARG A 540
 None
None
XYP  A1719 (-3.0A)
None
 1.20A 6hisA-1gqjA:
0.0
6hisB-1gqjA:
0.0		 6hisA-1gqjA:
8.62
6hisB-1gqjA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 8 ASP A 542
ILE A 333
ARG A 336
ARG A 540
 None
None
XYP  A1719 (-3.0A)
None
 1.20A 6hisB-1gqjA:
0.0
6hisC-1gqjA:
0.0		 6hisB-1gqjA:
8.62
6hisC-1gqjA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 8 ASP A 542
ILE A 333
ARG A 336
ARG A 540
 None
None
XYP  A1719 (-3.0A)
None
 1.20A 6hisC-1gqjA:
0.0
6hisD-1gqjA:
0.0		 6hisC-1gqjA:
8.62
6hisD-1gqjA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 8 ASP A 542
ILE A 333
ARG A 336
ARG A 540
 None
None
XYP  A1719 (-3.0A)
None
 1.20A 6hisD-1gqjA:
0.0
6hisE-1gqjA:
0.0		 6hisD-1gqjA:
8.62
6hisE-1gqjA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 8 ASP A 542
ILE A 333
ARG A 336
ARG A 540
 None
None
XYP  A1719 (-3.0A)
None
 1.20A 6hisA-1gqjA:
0.0
6hisE-1gqjA:
0.0		 6hisA-1gqjA:
8.62
6hisE-1gqjA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1gqj ALPHA-D-GLUCURONIDAS
E
(Cellvibrio
japonicus) 		4 / 5 LEU A 222
GLN A 223
PHE A 221
PHE A 282
 None
 1.37A 6nmpP-1gqjA:
undetectable
6nmpW-1gqjA:
undetectable		 6nmpP-1gqjA:
17.91
6nmpW-1gqjA:
7.36