SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1gqo DEHYDROQUINASE
(Bacillus
subtilis) 		5 / 11 GLU A  62
ALA A  59
ILE A  84
ALA A  83
ASP A  55
 None
 1.16A 3nmuB-1gqoA:
undetectable
3nmuJ-1gqoA:
undetectable		 3nmuB-1gqoA:
18.50
3nmuJ-1gqoA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1gqo DEHYDROQUINASE
(Bacillus
subtilis) 		5 / 9 ALA A 128
LEU A  34
LEU A  27
ASN A   7
ILE A   5
 None
 1.32A 3wdmA-1gqoA:
2.6		 3wdmA-1gqoA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1gqo DEHYDROQUINASE
(Bacillus
subtilis) 		4 / 8 ASP A  58
ILE A  57
GLY A  54
SER A 113
 None
 0.84A 4acbB-1gqoA:
6.3
4acbC-1gqoA:
3.1		 4acbB-1gqoA:
15.53
4acbC-1gqoA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1gqo DEHYDROQUINASE
(Bacillus
subtilis) 		5 / 10 GLU A  97
ALA A 119
ILE A  70
ALA A  87
ILE A  60
 None
 0.95A 4lbgA-1gqoA:
3.8		 4lbgA-1gqoA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 1gqo DEHYDROQUINASE
(Bacillus
subtilis) 		3 / 3 VAL A  71
TYR A 131
ALA A 134
 None
 0.48A 4ybnA-1gqoA:
undetectable		 4ybnA-1gqoA:
22.33