SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gqp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1gqp DOC1/APC10
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  67
GLY A 249
ILE A 250
PRO A 183
 None
 0.72A 2aojB-1gqpA:
undetectable		 2aojB-1gqpA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)		 1gqp DOC1/APC10
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  67
GLY A 249
ILE A 250
PRO A 183
VAL A 208
 None
 0.92A 3so9B-1gqpA:
undetectable		 3so9B-1gqpA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 1gqp DOC1/APC10
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 156
SER A 126
LEU A 234
LEU A 247
 None
 1.27A 4n09B-1gqpA:
undetectable		 4n09B-1gqpA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 1gqp DOC1/APC10
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 156
SER A 126
LEU A 234
LEU A 247
 None
 1.26A 4n09D-1gqpA:
undetectable		 4n09D-1gqpA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 1gqp DOC1/APC10
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 170
TRP A 211
VAL A 212
 None
 0.24A 4w9nC-1gqpA:
undetectable		 4w9nC-1gqpA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1gqp DOC1/APC10
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 235
HIS A 239
PRO A 183
LEU A 185
 None
 1.50A 5dzka-1gqpA:
undetectable
5dzko-1gqpA:
undetectable		 5dzka-1gqpA:
22.71
5dzko-1gqpA:
1.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1gqp DOC1/APC10
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 178
ASN A 238
PHE A 136
 None
 0.74A 5jglB-1gqpA:
undetectable		 5jglB-1gqpA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 1gqp DOC1/APC10
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 205
PRO A  95
PHE A 172
LEU A  98
 None
 1.22A 6aycA-1gqpA:
undetectable		 6aycA-1gqpA:
17.19