SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gqr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 GLY A 119
TYR A 334
TRP A 432
ILE A 439
HIS A 440
 EMM  A1999 (-3.5A)
None
None
None
EMM  A1999 ( 3.8A)
 1.24A 1acjA-1gqrA:
67.0		 1acjA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 9 TRP A  84
GLU A 199
PHE A 330
TYR A 334
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.5A)
SAF  A1998 (-3.1A)
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 1.38A 1acjA-1gqrA:
67.0		 1acjA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 TRP A  84
GLU A 443
TRP A 432
ILE A 439
GLY A 441
 SAF  A1998 (-3.8A)
None
None
None
SAF  A1998 ( 4.6A)
 1.41A 1acjA-1gqrA:
67.0		 1acjA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 9 TRP A  84
GLY A 117
TRP A 432
ILE A 439
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 1.03A 1acjA-1gqrA:
67.0		 1acjA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 9 TRP A  84
GLY A 118
GLU A 199
TYR A 334
TRP A 432
ILE A 439
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
SAF  A1998 (-3.5A)
None
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.59A 1acjA-1gqrA:
67.0		 1acjA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACL_A_DMEA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 10 TYR A  70
TRP A  84
TYR A 121
GLU A 199
SER A 200
TRP A 279
PHE A 330
TYR A 334
HIS A 440
GLY A 441
 None
SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
SAF  A1998 (-3.1A)
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.65A 1aclA-1gqrA:
66.6		 1aclA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 8 GLY A 119
TYR A 121
SER A 200
PHE A 331
HIS A 440
 EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.38A 1ax9A-1gqrA:
71.1		 1ax9A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 TRP A  84
GLU A 199
SER A 200
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.16A 1ax9A-1gqrA:
71.1		 1ax9A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.79A 1ax9A-1gqrA:
71.1		 1ax9A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 ASP A  72
GLY A 118
TYR A 121
SER A 200
PHE A 330
PHE A 331
 None
SAF  A1998 ( 3.5A)
None
EMM  A1999 ( 1.4A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 1.13A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		11 / 12 ASP A  72
TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 200
TRP A 233
PHE A 290
PHE A 330
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 0.43A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 0.91A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
SER A 200
TRP A 233
PHE A 290
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.72A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 TRP A  84
GLY A 117
TRP A 233
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.0A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.35A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 TRP A  84
GLY A 118
SER A 200
TRP A 233
PHE A 330
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
SAF  A1998 (-3.1A)
EMM  A1999 ( 3.8A)
 1.36A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		3 / 3 GLU A 462
TYR A 458
PHE A 446
 None
 0.89A 1eqbB-1gqrA:
undetectable		 1eqbB-1gqrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		3 / 3 GLU A 462
TYR A 458
PHE A 446
 None
 0.89A 1eqbA-1gqrA:
undetectable		 1eqbA-1gqrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		3 / 3 GLU A 462
TYR A 458
PHE A 446
 None
 0.89A 1eqbD-1gqrA:
undetectable		 1eqbD-1gqrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		3 / 3 GLU A 462
TYR A 458
PHE A 446
 None
 0.90A 1eqbC-1gqrA:
undetectable		 1eqbC-1gqrA:
20.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 10 GLY A 118
TYR A 121
GLU A 199
TRP A 279
LEU A 282
PHE A 288
 SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
None
None
EMM  A1999 (-4.3A)
 0.99A 1eveA-1gqrA:
68.9		 1eveA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 10 GLY A 119
TYR A 121
TRP A 279
PHE A 331
TYR A 334
HIS A 440
 EMM  A1999 (-3.5A)
None
None
EMM  A1999 (-4.7A)
None
EMM  A1999 ( 3.8A)
 1.35A 1eveA-1gqrA:
68.9		 1eveA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 10 TRP A  84
GLY A 118
TYR A 121
GLU A 199
TRP A 279
LEU A 282
PHE A 330
PHE A 331
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
None
None
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
None
EMM  A1999 ( 3.8A)
 0.61A 1eveA-1gqrA:
68.9		 1eveA-1gqrA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 203
VAL A 206
ILE A 115
TYR A 148
GLY A 117
 None
None
None
None
SAF  A1998 (-3.1A)
 1.39A 1fohA-1gqrA:
undetectable		 1fohA-1gqrA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 203
VAL A 206
ILE A 115
TYR A 148
GLY A 117
 None
None
None
None
SAF  A1998 (-3.1A)
 1.40A 1fohB-1gqrA:
0.0		 1fohB-1gqrA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 203
VAL A 206
ILE A 115
TYR A 148
GLY A 117
 None
None
None
None
SAF  A1998 (-3.1A)
 1.37A 1fohC-1gqrA:
0.0		 1fohC-1gqrA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 203
VAL A 206
ILE A 115
TYR A 148
GLY A 117
 None
None
None
None
SAF  A1998 (-3.1A)
 1.39A 1fohD-1gqrA:
undetectable		 1fohD-1gqrA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 PHE A 331
PHE A 290
TYR A 421
GLY A 203
SER A 200
GLY A 118
 EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
None
None
EMM  A1999 ( 1.4A)
SAF  A1998 ( 3.5A)
 1.44A 1igxA-1gqrA:
0.0		 1igxA-1gqrA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 PHE A 331
PHE A 290
TYR A 421
GLY A 227
SER A 200
GLY A 118
 EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
None
None
EMM  A1999 ( 1.4A)
SAF  A1998 ( 3.5A)
 1.35A 1igxA-1gqrA:
0.0		 1igxA-1gqrA:
22.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 119
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
 EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 1.30A 1maaA-1gqrA:
59.7		 1maaA-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 12 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
PHE A 290
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.1A)
None
EMM  A1999 ( 3.8A)
 0.72A 1maaA-1gqrA:
59.7		 1maaA-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 TYR A  70
ASP A  72
GLY A 119
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
 None
None
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
 1.16A 1maaA-1gqrA:
59.7		 1maaA-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TYR A  70
ASP A  72
TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
PHE A 290
TYR A 334
 None
None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.1A)
None
 0.56A 1maaA-1gqrA:
59.7		 1maaA-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 6 TRP A  84
TYR A 121
GLU A 199
ILE A 287
 SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
 0.56A 1maaB-1gqrA:
61.6
1maaD-1gqrA:
59.7		 1maaB-1gqrA:
58.56
1maaD-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 6 TRP A  84
TYR A 121
GLU A 199
TYR A 334
 SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
 0.57A 1maaB-1gqrA:
61.6
1maaD-1gqrA:
59.7		 1maaB-1gqrA:
58.56
1maaD-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 TRP A  84
GLY A 117
SER A 200
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.25A 1maaC-1gqrA:
61.2		 1maaC-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 TYR A  70
GLY A 118
TYR A 121
TYR A 130
SER A 200
TRP A 279
PHE A 288
 None
SAF  A1998 ( 3.5A)
None
None
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.3A)
 1.02A 1maaC-1gqrA:
61.2		 1maaC-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 TYR A  70
GLY A 119
TYR A 121
SER A 200
TRP A 279
PHE A 331
HIS A 440
 None
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.48A 1maaC-1gqrA:
61.2		 1maaC-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		11 / 12 TYR A  70
TRP A  84
GLY A 118
TYR A 121
TYR A 130
SER A 200
TRP A 279
PHE A 290
PHE A 331
TYR A 334
HIS A 440
 None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
None
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
None
EMM  A1999 ( 3.8A)
 0.86A 1maaC-1gqrA:
61.2		 1maaC-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 GLY A 119
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
 EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 1.30A 1maaD-1gqrA:
59.7		 1maaD-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 8 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 0.73A 1maaD-1gqrA:
59.7		 1maaD-1gqrA:
58.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		3 / 3 ILE A 401
LEU A 404
VAL A 408
 None
 0.38A 1mz9B-1gqrA:
undetectable		 1mz9B-1gqrA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 6 PHE A 423
ASN A 324
ILE A 444
GLY A 441
 None
None
None
SAF  A1998 ( 4.6A)
 0.95A 1oniA-1gqrA:
0.0
1oniB-1gqrA:
0.4		 1oniA-1gqrA:
14.53
1oniB-1gqrA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 6 PHE A 423
ASN A 324
ILE A 444
GLY A 441
 None
None
None
SAF  A1998 ( 4.6A)
 0.96A 1oniD-1gqrA:
0.0
1oniF-1gqrA:
0.5		 1oniD-1gqrA:
14.53
1oniF-1gqrA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 7 ILE A 444
GLY A 441
PHE A 423
ASN A 324
 None
SAF  A1998 ( 4.6A)
None
None
 0.98A 1oniG-1gqrA:
0.0
1oniI-1gqrA:
1.9		 1oniG-1gqrA:
14.53
1oniI-1gqrA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 203
VAL A 206
ILE A 115
TYR A 148
GLY A 117
 None
None
None
None
SAF  A1998 (-3.1A)
 1.44A 1pn0A-1gqrA:
0.3		 1pn0A-1gqrA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 203
VAL A 206
ILE A 115
TYR A 148
GLY A 117
 None
None
None
None
SAF  A1998 (-3.1A)
 1.42A 1pn0B-1gqrA:
0.0		 1pn0B-1gqrA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 203
VAL A 206
ILE A 115
TYR A 148
GLY A 117
 None
None
None
None
SAF  A1998 (-3.1A)
 1.38A 1pn0C-1gqrA:
0.0		 1pn0C-1gqrA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 203
VAL A 206
ILE A 115
TYR A 148
GLY A 117
 None
None
None
None
SAF  A1998 (-3.1A)
 1.37A 1pn0D-1gqrA:
0.0		 1pn0D-1gqrA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 LEU A   6
VAL A  15
GLY A  17
ALA A  60
SER A  61
 None
None
None
None
NAG  A1996 (-3.6A)
 1.28A 1pxxB-1gqrA:
0.0		 1pxxB-1gqrA:
23.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 ASP A  72
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 331
 None
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
 1.33A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		11 / 12 ASP A  72
TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 288
PHE A 290
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
 0.46A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 GLY A 117
GLY A 118
GLY A 119
GLU A 199
SER A 200
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.01A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 0.99A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 GLY A 202
GLU A 199
SER A 200
PHE A 288
PHE A 290
HIS A 440
 None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.43A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
GLU A 199
SER A 200
PHE A 288
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.71A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1U65_A_CP0A1000_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 11 GLN A  74
TRP A  84
TYR A 121
GLU A 199
TRP A 279
LEU A 282
ASP A 285
TYR A 334
HIS A 440
 None
SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
None
None
None
EMM  A1999 ( 3.8A)
 0.94A 1u65A-1gqrA:
68.0		 1u65A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1U65_A_CP0A1000_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 11 TYR A  70
GLN A  74
TRP A  84
TYR A 121
GLU A 199
TRP A 279
LEU A 282
ASP A 285
PHE A 330
TYR A 334
 None
None
SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
None
None
SAF  A1998 (-3.1A)
None
 0.77A 1u65A-1gqrA:
68.0		 1u65A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 ASP A  72
TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 200
PHE A 288
PHE A 290
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
 0.42A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 ASP A  72
TRP A  84
GLY A 117
GLY A 118
SER A 200
PHE A 288
PHE A 330
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 0.79A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
SER A 200
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.08A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 0.93A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
SER A 200
PHE A 288
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.72A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 11 ASP A  72
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 330
PHE A 331
 None
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 1.09A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 11 ASP A  72
TRP A  84
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 330
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 0.41A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 11 GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 0.97A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 11 GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.21A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 11 TRP A  84
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.65A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 10 ASP A  72
TRP A  84
GLY A 117
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
 0.44A 1w76B-1gqrA:
69.1		 1w76B-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 10 GLY A 117
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 1.03A 1w76B-1gqrA:
69.1		 1w76B-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 202
GLU A 199
SER A 200
PHE A 290
HIS A 440
 None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.30A 1w76B-1gqrA:
69.1		 1w76B-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 10 TRP A  84
GLY A 117
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.69A 1w76B-1gqrA:
69.1		 1w76B-1gqrA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 5 TRP A 473
ILE A 223
LEU A 135
ALA A 474
 None
 0.94A 1xvaA-1gqrA:
2.0
1xvaB-1gqrA:
2.0		 1xvaA-1gqrA:
18.66
1xvaB-1gqrA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 6 ALA A 474
TRP A 473
ILE A 223
LEU A 135
 None
 1.01A 1xvaA-1gqrA:
2.0
1xvaB-1gqrA:
2.0		 1xvaA-1gqrA:
18.66
1xvaB-1gqrA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 MET A 208
ARG A 216
ILE A 196
PHE A 155
PHE A 120
 None
 0.99A 1y0xX-1gqrA:
0.0		 1y0xX-1gqrA:
19.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 ALA A 234
PHE A 300
GLY A 207
SER A 200
LEU A 224
 None
None
None
EMM  A1999 ( 1.4A)
None
 0.95A 1ya4A-1gqrA:
52.5		 1ya4A-1gqrA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 GLY A 117
GLY A 118
GLY A 119
SER A 200
ALA A 201
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 ( 3.8A)
 0.59A 1yajC-1gqrA:
49.9		 1yajC-1gqrA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 8 GLY A 118
GLY A 119
SER A 200
ALA A 201
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 ( 3.8A)
 1.06A 1yajC-1gqrA:
49.9		 1yajC-1gqrA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 8 GLY A 202
GLY A 117
GLY A 118
SER A 200
ALA A 201
 None
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
 1.09A 1yajC-1gqrA:
49.9		 1yajC-1gqrA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 GLY A 117
GLY A 118
SER A 200
ALA A 201
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 ( 3.8A)
 0.95A 2aceA-1gqrA:
69.0		 2aceA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 9 GLY A 118
GLY A 119
SER A 200
ALA A 201
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.06A 2aceA-1gqrA:
69.0		 2aceA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 9 GLY A 118
GLY A 119
SER A 200
ALA A 201
TRP A 233
PHE A 288
PHE A 290
PHE A 330
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 ( 3.8A)
 0.73A 2aceA-1gqrA:
69.0		 2aceA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 7 GLY A 118
GLU A 199
SER A 200
PHE A 288
 SAF  A1998 ( 3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
 1.06A 2ackA-1gqrA:
69.7		 2ackA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 7 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.81A 2ackA-1gqrA:
69.7		 2ackA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 ASP A  72
TRP A  84
TYR A 121
TRP A 279
TYR A 334
HIS A 440
 None
SAF  A1998 (-3.8A)
None
None
None
EMM  A1999 ( 3.8A)
 0.76A 2ha2A-1gqrA:
60.6		 2ha2A-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 TYR A  70
ASP A  72
TRP A  84
TYR A 121
TRP A 279
TYR A 334
 None
None
SAF  A1998 (-3.8A)
None
None
None
 0.42A 2ha2A-1gqrA:
60.6		 2ha2A-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 TYR A  70
ASP A  72
TRP A  84
TYR A 121
TRP A 279
TYR A 334
HIS A 440
 None
None
SAF  A1998 (-3.8A)
None
None
None
EMM  A1999 ( 3.8A)
 0.70A 2ha2B-1gqrA:
61.5		 2ha2B-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA545_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 4 TYR A  70
TYR A 121
TRP A 279
TYR A 334
 None
 0.50A 2ha4A-1gqrA:
60.4		 2ha4A-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 TRP A  84
TYR A 121
TYR A 130
GLU A 199
PHE A 331
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
None
None
SAF  A1998 (-3.5A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.75A 2ha4A-1gqrA:
60.4		 2ha4A-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 GLY A 118
GLY A 119
ALA A 201
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.12A 2ha4A-1gqrA:
60.4		 2ha4A-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 GLY A 118
GLY A 119
ALA A 201
TRP A 233
PHE A 288
PHE A 290
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 0.67A 2ha4A-1gqrA:
60.4		 2ha4A-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACHB602_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 4 TYR A  70
TYR A 121
TRP A 279
TYR A 334
 None
 0.60A 2ha4B-1gqrA:
62.0		 2ha4B-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 7 TRP A  84
TYR A 121
TYR A 130
GLU A 199
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
None
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.62A 2ha4B-1gqrA:
62.0		 2ha4B-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 7 GLY A 118
GLY A 119
ALA A 201
TRP A 233
PHE A 290
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 0.62A 2ha4B-1gqrA:
62.0		 2ha4B-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 9 TYR A  70
ASP A  72
TRP A  84
TYR A 121
GLU A 199
TRP A 279
TYR A 334
 None
None
SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
None
 0.47A 2ha6A-1gqrA:
60.9		 2ha6A-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 10 GLU A  82
MET A  83
ASN A  85
ASP A 128
GLU A 445
LEU A 450
LEU A 456
TYR A 458
 None
 0.59A 2ha6A-1gqrA:
60.9		 2ha6A-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 9 TYR A  70
TRP A  84
TYR A 121
TRP A 279
PHE A 331
TYR A 334
HIS A 440
GLY A 441
 None
SAF  A1998 (-3.8A)
None
None
EMM  A1999 (-4.7A)
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.82A 2ha6B-1gqrA:
61.5		 2ha6B-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_B_SCKB952_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 10 GLU A  82
MET A  83
ASN A  85
ASP A 128
GLU A 445
LEU A 450
LEU A 456
TYR A 458
 None
 0.64A 2ha6B-1gqrA:
61.5		 2ha6B-1gqrA:
58.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 5 ASP A 393
MET A 405
LEU A 420
HIS A 513
 None
 1.29A 2jfaA-1gqrA:
undetectable		 2jfaA-1gqrA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 7 GLY A 202
VAL A 323
SER A 228
LEU A 404
 None
 0.83A 2oa1B-1gqrA:
undetectable		 2oa1B-1gqrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 ILE A 115
GLY A 227
GLY A 198
ASN A 399
PHE A 290
 None
None
None
None
EMM  A1999 (-4.1A)
 1.14A 2okcB-1gqrA:
2.2		 2okcB-1gqrA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 5 ASP A 393
MET A 405
LEU A 420
HIS A 513
 None
 1.30A 2qxsB-1gqrA:
0.0		 2qxsB-1gqrA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 GLY A 118
GLY A 154
GLY A 151
SER A 122
LEU A 156
 SAF  A1998 ( 3.5A)
None
None
None
None
 1.02A 2wa2A-1gqrA:
undetectable		 2wa2A-1gqrA:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XUD_A_DMEA1544_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 6 TRP A  84
TYR A 121
TRP A 279
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
None
None
None
EMM  A1999 ( 3.8A)
 0.75A 2xudA-1gqrA:
59.8		 2xudA-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XUD_A_DMEA1544_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 6 TYR A  70
TRP A  84
TYR A 121
TRP A 279
TYR A 334
 None
SAF  A1998 (-3.8A)
None
None
None
 0.45A 2xudA-1gqrA:
59.8		 2xudA-1gqrA:
58.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 LEU A 156
PRO A 165
GLY A 154
GLY A 169
ILE A 263
 None
 0.98A 3axzA-1gqrA:
0.0		 3axzA-1gqrA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 6 ALA A 136
LEU A 135
ALA A 474
THR A 475
 None
 0.81A 3b6hA-1gqrA:
0.0		 3b6hA-1gqrA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 6 ALA A 136
LEU A 135
ALA A 474
THR A 475
 None
 0.86A 3b6hB-1gqrA:
0.0		 3b6hB-1gqrA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 PHE A 407
GLY A 117
GLY A 203
SER A 205
LEU A 224
 None
SAF  A1998 (-3.1A)
None
None
None
 1.06A 3e23A-1gqrA:
undetectable		 3e23A-1gqrA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		3 / 3 ARG A 216
ILE A 319
THR A 497
 None
 0.71A 3ia4D-1gqrA:
undetectable		 3ia4D-1gqrA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 GLY A 384
ILE A 394
PHE A 331
PHE A 339
GLY A 338
 None
None
EMM  A1999 (-4.7A)
None
None
 1.45A 3ko0A-1gqrA:
1.4
3ko0C-1gqrA:
1.4		 3ko0A-1gqrA:
11.35
3ko0C-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 GLY A 437
PHE A 290
PHE A 330
GLY A 328
PHE A 331
 None
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
None
EMM  A1999 (-4.7A)
 1.47A 3ko0A-1gqrA:
1.4
3ko0C-1gqrA:
1.4		 3ko0A-1gqrA:
11.35
3ko0C-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 PHE A 339
GLY A 338
GLY A 384
ILE A 394
PHE A 331
 None
None
None
None
EMM  A1999 (-4.7A)
 1.41A 3ko0H-1gqrA:
1.4
3ko0I-1gqrA:
1.5		 3ko0H-1gqrA:
11.35
3ko0I-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 PHE A 339
GLY A 338
GLY A 384
ILE A 394
PHE A 331
 None
None
None
None
EMM  A1999 (-4.7A)
 1.42A 3ko0L-1gqrA:
1.3
3ko0N-1gqrA:
1.9		 3ko0L-1gqrA:
11.35
3ko0N-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 384
ILE A 394
PHE A 331
PHE A 339
GLY A 338
 None
None
EMM  A1999 (-4.7A)
None
None
 1.42A 3ko0R-1gqrA:
1.5
3ko0T-1gqrA:
1.3		 3ko0R-1gqrA:
11.35
3ko0T-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 437
PHE A 290
PHE A 330
GLY A 328
PHE A 331
 None
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
None
EMM  A1999 (-4.7A)
 1.50A 3ko0R-1gqrA:
1.5
3ko0T-1gqrA:
1.3		 3ko0R-1gqrA:
11.35
3ko0T-1gqrA:
11.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 7 GLY A 118
GLY A 119
SER A 200
TRP A 233
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 ( 3.8A)
 0.56A 3o9mA-1gqrA:
61.5		 3o9mA-1gqrA:
53.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 6 GLY A 118
GLY A 119
SER A 200
TRP A 233
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 ( 3.8A)
 0.62A 3o9mB-1gqrA:
61.5		 3o9mB-1gqrA:
53.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 LEU A 127
TYR A 130
SER A 200
SER A 226
PHE A 330
 None
None
EMM  A1999 ( 1.4A)
None
SAF  A1998 (-3.1A)
 1.49A 3ug8A-1gqrA:
undetectable		 3ug8A-1gqrA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 8 GLY A 117
GLY A 118
SER A 200
GLY A 227
VAL A 400
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
None
None
 1.42A 3v1nA-1gqrA:
12.5		 3v1nA-1gqrA:
19.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BDS_A_THAA701_1
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 9 TRP A  84
GLU A 199
SER A 200
TYR A 334
TRP A 432
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.53A 4bdsA-1gqrA:
59.3		 4bdsA-1gqrA:
53.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 8 LEU A  97
THR A  62
TYR A  96
PHE A  35
 None
NAG  A1996 ( 4.3A)
None
None
 1.08A 4drjB-1gqrA:
undetectable		 4drjB-1gqrA:
11.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
SER A 200
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.12A 4ey6A-1gqrA:
61.5		 4ey6A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 122
SER A 200
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
 0.85A 4ey6A-1gqrA:
61.5		 4ey6A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
SER A 122
SER A 200
PHE A 288
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.75A 4ey6A-1gqrA:
61.5		 4ey6A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 122
SER A 200
PHE A 288
PHE A 290
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
 0.41A 4ey6A-1gqrA:
61.5		 4ey6A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 GLY A 117
GLY A 118
GLY A 119
GLU A 199
SER A 200
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.11A 4ey6B-1gqrA:
59.7		 4ey6B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
 0.85A 4ey6B-1gqrA:
59.7		 4ey6B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
GLU A 199
SER A 200
PHE A 288
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.79A 4ey6B-1gqrA:
59.7		 4ey6B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 288
PHE A 290
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
 0.44A 4ey6B-1gqrA:
59.7		 4ey6B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 11 TYR A  70
GLY A 119
TYR A 121
SER A 200
TRP A 279
TYR A 334
HIS A 440
 None
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 1.33A 4ey7A-1gqrA:
61.2		 4ey7A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 11 TYR A  70
TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
GLY A 441
 None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.80A 4ey7A-1gqrA:
61.2		 4ey7A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 11 GLY A 119
TYR A 121
SER A 200
TRP A 279
TYR A 334
HIS A 440
 EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 1.40A 4ey7B-1gqrA:
61.1		 4ey7B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 11 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.84A 4ey7B-1gqrA:
61.1		 4ey7B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 11 TYR A  70
GLY A 119
TYR A 121
SER A 200
TRP A 279
TYR A 334
 None
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
None
None
 1.28A 4ey7B-1gqrA:
61.1		 4ey7B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 11 TYR A  70
TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
GLY A 441
 None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
SAF  A1998 ( 4.6A)
 0.69A 4ey7B-1gqrA:
61.1		 4ey7B-1gqrA:
57.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 8 ILE A 223
ILE A 469
PHE A 448
GLY A 132
 None
 0.87A 4hdlA-1gqrA:
0.0		 4hdlA-1gqrA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA608_0
(SERUM ALBUMIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 4 PRO A  48
ASP A 172
LEU A 171
ARG A 174
 None
 1.27A 4luhA-1gqrA:
0.2		 4luhA-1gqrA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 ILE A 184
GLY A 189
PRO A 106
PHE A 187
VAL A 111
 None
 1.12A 4rvdA-1gqrA:
2.7		 4rvdA-1gqrA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 ILE A 184
GLY A 189
PRO A 106
PHE A 187
VAL A 111
 None
 1.11A 4rvgA-1gqrA:
3.1		 4rvgA-1gqrA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 4 ALA A 136
VAL A 101
GLY A 189
THR A 109
 None
 1.04A 4ubeA-1gqrA:
3.4		 4ubeA-1gqrA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 LEU A 156
PRO A 165
GLY A 154
GLY A 169
ILE A 263
 None
 0.90A 4yvgA-1gqrA:
undetectable		 4yvgA-1gqrA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 7 VAL A 113
ILE A 196
PHE A 219
VAL A 194
ILE A 184
 None
 1.39A 5bmvC-1gqrA:
undetectable		 5bmvC-1gqrA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 LEU A 256
LEU A 248
GLY A 249
LEU A 262
LEU A 158
 None
 1.10A 5dqfA-1gqrA:
2.6		 5dqfA-1gqrA:
20.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E2I_A_DMEA605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 6 TYR A  70
ASP A  72
TYR A 121
TRP A 279
PHE A 330
TYR A 334
 None
None
None
None
SAF  A1998 (-3.1A)
None
 0.21A 5e2iA-1gqrA:
67.4		 5e2iA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E4J_A_DMEA608_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 9 TYR A  70
TRP A  84
TYR A 121
GLU A 199
TRP A 279
PHE A 330
TYR A 334
HIS A 440
GLY A 441
 None
SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
SAF  A1998 (-3.1A)
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.63A 5e4jA-1gqrA:
68.0		 5e4jA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 6 TYR A  70
TYR A 121
ASP A 276
TRP A 279
TYR A 334
 None
 0.81A 5ov9A-1gqrA:
59.3		 5ov9A-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 7 TYR A  70
TYR A 121
GLN A 272
ASP A 276
TRP A 279
TYR A 334
 None
 0.86A 5ov9B-1gqrA:
61.3		 5ov9B-1gqrA:
58.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 8 VAL A  71
ASP A  72
GLU A  73
GLY A  77
 None
 0.75A 5w3jB-1gqrA:
2.2		 5w3jB-1gqrA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		3 / 3 GLU A 443
TRP A 114
HIS A 440
 None
None
EMM  A1999 ( 3.8A)
 0.96A 5xipA-1gqrA:
1.1		 5xipA-1gqrA:
21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6EP4_A_DMEA601_1
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 5 TRP A  84
TYR A 130
GLU A 199
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
EMM  A1999 ( 3.8A)
 0.57A 6ep4A-1gqrA:
61.9		 6ep4A-1gqrA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 8 GLY A 118
SER A 200
PHE A 331
TYR A 334
 SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
None
 0.66A 6eqpA-1gqrA:
61.0		 6eqpA-1gqrA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 TRP A  84
GLY A 119
SER A 200
TRP A 233
PHE A 331
TYR A 334
 SAF  A1998 (-3.8A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.7A)
None
 0.59A 6eqpA-1gqrA:
61.0		 6eqpA-1gqrA:
46.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 11 HIS A 440
TYR A 121
GLY A 118
SER A 200
PHE A 331
 EMM  A1999 ( 3.8A)
None
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
 1.16A 6ieyA-1gqrA:
18.0
6ieyB-1gqrA:
18.4		 6ieyA-1gqrA:
20.34
6ieyB-1gqrA:
20.34