SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1gri GROWTH FACTOR BOUND
PROTEIN 2
(Homo
sapiens) 		5 / 12 PHE A 167
GLY A 176
ILE A 183
ALA A 163
VAL A 210
 None
 1.13A 4dx5B-1griA:
undetectable		 4dx5B-1griA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1gri GROWTH FACTOR BOUND
PROTEIN 2
(Homo
sapiens) 		5 / 12 PHE A 167
GLY A 176
ILE A 183
ALA A 163
VAL A 210
 None
 1.08A 4u8vB-1griA:
undetectable		 4u8vB-1griA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1gri GROWTH FACTOR BOUND
PROTEIN 2
(Homo
sapiens) 		5 / 12 PHE A 167
GLY A 176
ILE A 183
ALA A 163
VAL A 210
 None
 1.13A 4u8yB-1griA:
0.0		 4u8yB-1griA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1gri GROWTH FACTOR BOUND
PROTEIN 2
(Homo
sapiens) 		5 / 12 PHE A 167
GLY A 176
ILE A 183
ALA A 163
VAL A 210
 None
 1.10A 4u95B-1griA:
0.0		 4u95B-1griA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 1gri GROWTH FACTOR BOUND
PROTEIN 2
(Homo
sapiens) 		5 / 11 SER A  75
ASP A 104
GLU A  71
ARG A  67
ARG A  86
 None
 1.34A 4urnA-1griA:
undetectable		 4urnA-1griA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 1gri GROWTH FACTOR BOUND
PROTEIN 2
(Homo
sapiens) 		5 / 11 SER A  75
ASP A 104
GLU A  71
ARG A  67
ARG A  86
 None
 1.41A 4urnC-1griA:
undetectable		 4urnC-1griA:
20.24