SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1grj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 1grj GREA PROTEIN
(Escherichia
coli) 		5 / 10 LEU A  21
GLU A  17
ILE A  62
ILE A   4
LEU A  69
 None
 0.88A 1wopA-1grjA:
undetectable		 1wopA-1grjA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1grj GREA PROTEIN
(Escherichia
coli) 		4 / 8 GLU A  47
HIS A  39
ASN A  45
ILE A  33
 None
 1.29A 3kp6A-1grjA:
2.6
3kp6B-1grjA:
2.3		 3kp6A-1grjA:
22.09
3kp6B-1grjA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1grj GREA PROTEIN
(Escherichia
coli) 		4 / 8 VAL A 122
ALA A 127
GLY A 129
GLY A 132
 None
 0.82A 5e26C-1grjA:
undetectable
5e26D-1grjA:
undetectable		 5e26C-1grjA:
19.23
5e26D-1grjA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1grj GREA PROTEIN
(Escherichia
coli) 		5 / 12 ILE A 126
GLY A 129
ARG A 128
ASN A  96
PHE A 150
 None
 1.35A 5fhzA-1grjA:
undetectable		 5fhzA-1grjA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1grj GREA PROTEIN
(Escherichia
coli) 		5 / 8 VAL A  86
ILE A 131
ALA A 127
VAL A  94
VAL A  92
 None
 1.24A 5l94A-1grjA:
undetectable		 5l94A-1grjA:
17.12