SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gsq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 7 TYR A   7
PHE A   8
GLY A  12
ARG A  13
 None
GDN  A 203 (-4.5A)
None
GDN  A 203 (-4.9A)
 0.46A 11gsB-1gsqA:
25.7		 11gsB-1gsqA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 11 ALA A  22
LEU A  21
SER A  63
ILE A  66
ALA A  67
 None
None
GDN  A 203 (-2.6A)
None
None
 0.93A 1ha2A-1gsqA:
undetectable		 1ha2A-1gsqA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		3 / 3 ILE A 177
LEU A 180
VAL A 184
 None
 0.29A 1mz9B-1gsqA:
undetectable		 1mz9B-1gsqA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		3 / 3 ASP A  77
ARG A  72
ASP A  88
 None
 0.83A 1vptA-1gsqA:
undetectable		 1vptA-1gsqA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 9 THR A  91
HIS A  69
ALA A  71
LEU A  76
GLU A  26
 None
 1.45A 2azqA-1gsqA:
0.5		 2azqA-1gsqA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 9 LEU A 170
LEU A 171
ILE A 177
LEU A  94
ILE A  97
 None
 1.06A 2f78A-1gsqA:
undetectable		 2f78A-1gsqA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 9 LEU A 170
LEU A 171
ILE A 177
LEU A  94
ILE A  97
 None
 1.09A 2f78B-1gsqA:
undetectable		 2f78B-1gsqA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 9 LEU A 170
LEU A 171
ILE A 177
LEU A  94
ILE A  97
 None
 1.02A 2f7aA-1gsqA:
0.7		 2f7aA-1gsqA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 9 LEU A 170
LEU A 171
ILE A 177
LEU A  94
ILE A  97
 None
 1.05A 2f7aB-1gsqA:
1.3		 2f7aB-1gsqA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 10 LEU A 170
LEU A 171
ILE A 177
LEU A  94
ILE A  97
 None
 1.06A 2f8dA-1gsqA:
0.5		 2f8dA-1gsqA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 10 LEU A 170
LEU A 171
ILE A 177
LEU A  94
ILE A  97
 None
 1.06A 2f8dB-1gsqA:
undetectable		 2f8dB-1gsqA:
19.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 TYR A   7
PHE A   8
ARG A  13
TRP A  38
 None
GDN  A 203 (-4.5A)
GDN  A 203 (-4.9A)
GDN  A 203 (-4.1A)
 0.60A 2gssA-1gsqA:
25.7		 2gssA-1gsqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 TYR A   7
PHE A   8
ARG A  13
TRP A  38
 None
GDN  A 203 (-4.5A)
GDN  A 203 (-4.9A)
GDN  A 203 (-4.1A)
 0.60A 2gssB-1gsqA:
25.7		 2gssB-1gsqA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 5 LEU A  21
ALA A  23
LEU A 154
MET A  64
 None
 1.02A 2oaxA-1gsqA:
undetectable		 2oaxA-1gsqA:
19.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 9 TYR A   7
PHE A   8
PRO A   9
GLY A  12
ARG A  13
 None
GDN  A 203 (-4.5A)
None
None
GDN  A 203 (-4.9A)
 0.64A 3csjB-1gsqA:
25.8		 3csjB-1gsqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 TYR A   7
PHE A   8
ARG A  13
TRP A  38
 None
GDN  A 203 (-4.5A)
GDN  A 203 (-4.9A)
GDN  A 203 (-4.1A)
 0.64A 3n9jA-1gsqA:
25.7		 3n9jA-1gsqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 TYR A   7
PHE A   8
GLY A  12
ARG A  13
 None
GDN  A 203 (-4.5A)
None
GDN  A 203 (-4.9A)
 0.50A 3n9jB-1gsqA:
25.6		 3n9jB-1gsqA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		3 / 3 ASP A  77
ARG A  72
ASP A  88
 None
 0.78A 4fzvA-1gsqA:
undetectable		 4fzvA-1gsqA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 MET A  64
LEU A  21
HIS A 155
LEU A 151
 None
 0.98A 5dxeA-1gsqA:
undetectable		 5dxeA-1gsqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 MET A  64
LEU A  21
HIS A 155
LEU A 151
 None
 0.98A 6cbzA-1gsqA:
undetectable		 6cbzA-1gsqA:
18.97