SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gt9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 8 THR 1 217
ASN 1 322
THR 1 206
GLY 1 320
 None
 1.02A 1bu5B-1gt91:
undetectable		 1bu5B-1gt91:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 ARG 1 248
LEU 1 309
LEU 1 302
LEU 1 188
ASP 1 252
 None
 1.20A 1e7wA-1gt91:
2.2		 1e7wA-1gt91:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 ARG 1 248
SER 1 229
LEU 1 302
LEU 1 188
ASP 1 252
 None
 1.29A 1e7wA-1gt91:
2.2		 1e7wA-1gt91:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 LEU 1 355
LEU 1 356
ILE 1 349
LEU 1 287
LEU 1 188
 None
 1.19A 1errB-1gt91:
undetectable		 1errB-1gt91:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		6 / 12 GLY 1  92
ALA 1  93
ILE 1 124
PRO 1 282
ILE 1  30
ILE 1  28
 None
 1.40A 1hshA-1gt91:
undetectable		 1hshA-1gt91:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 TRP 1 208
GLY 1 192
VAL 1 207
ALA 1 281
GLY 1 166
 None
 1.14A 1kiaB-1gt91:
undetectable		 1kiaB-1gt91:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 6 LEU 1 343
ASP 1 252
LEU 1 188
ARG 1 248
 None
 0.74A 1mt1A-1gt91:
0.0
1mt1F-1gt91:
0.0		 1mt1A-1gt91:
9.86
1mt1F-1gt91:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 6 ARG 1 248
LEU 1 343
ASP 1 252
LEU 1 188
 None
 0.77A 1mt1B-1gt91:
0.0
1mt1C-1gt91:
0.0		 1mt1B-1gt91:
13.55
1mt1C-1gt91:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 6 LEU 1 343
ASP 1 252
LEU 1 188
ARG 1 248
 None
 0.79A 1mt1G-1gt91:
0.0
1mt1J-1gt91:
0.0		 1mt1G-1gt91:
9.86
1mt1J-1gt91:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 ARG 1 248
LEU 1 343
ASP 1 252
LEU 1 188
 None
 0.80A 1mt1H-1gt91:
0.0
1mt1K-1gt91:
0.0		 1mt1H-1gt91:
13.55
1mt1K-1gt91:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 5 ARG 1 248
LEU 1 343
ASP 1 252
LEU 1 188
 None
 0.71A 1n13B-1gt91:
0.0
1n13C-1gt91:
0.0		 1n13B-1gt91:
13.55
1n13C-1gt91:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 ARG 1 248
LEU 1 343
ASP 1 252
LEU 1 188
 None
 0.75A 1n13D-1gt91:
undetectable
1n13E-1gt91:
0.0		 1n13D-1gt91:
13.55
1n13E-1gt91:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 8 LEU 1 343
ASP 1 252
LEU 1 188
ARG 1 248
 None
 0.72A 1n13A-1gt91:
0.0
1n13F-1gt91:
0.0		 1n13A-1gt91:
9.86
1n13F-1gt91:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 6 ARG 1 248
LEU 1 343
ASP 1 252
LEU 1 188
 None
 0.79A 1n13H-1gt91:
0.0
1n13K-1gt91:
0.0		 1n13H-1gt91:
13.55
1n13K-1gt91:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 LEU 1 343
ASP 1 252
LEU 1 188
ARG 1 248
 None
 0.76A 1n13G-1gt91:
0.0
1n13J-1gt91:
0.0		 1n13G-1gt91:
9.86
1n13J-1gt91:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 LEU 1 343
ASP 1 252
LEU 1 188
ARG 1 248
 None
 0.71A 1n13I-1gt91:
0.0
1n13L-1gt91:
0.0		 1n13I-1gt91:
9.86
1n13L-1gt91:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 TRP 1 208
GLY 1 192
VAL 1 207
ALA 1 281
GLY 1 166
 None
 1.12A 1nbiB-1gt91:
2.3		 1nbiB-1gt91:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 ASN 1 292
GLY 1 296
LEU 1 356
THR 1 157
ILE 1 124
 None
 1.15A 1p93B-1gt91:
undetectable		 1p93B-1gt91:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 7 MET 1 144
ALA 1 142
ILE 1 141
ASP 1 104
PHE 1 107
 None
 1.49A 1upfB-1gt91:
undetectable		 1upfB-1gt91:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 THR 1 341
ILE 1 324
GLY 1 166
GLY 1 219
GLY 1 170
 None
 0.94A 2fk8A-1gt91:
2.1		 2fk8A-1gt91:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 ILE 1 291
LEU 1 287
ASN 1 292
VAL 1 313
VAL 1 253
 None
 1.02A 2nnhA-1gt91:
0.0		 2nnhA-1gt91:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		3 / 3 LEU 1 351
LEU 1 283
PHE 1 314
 None
 0.72A 2pgrA-1gt91:
undetectable		 2pgrA-1gt91:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 ARG 1 248
LEU 1 343
ASP 1 252
LEU 1 188
 None
 0.69A 2qqcB-1gt91:
0.0
2qqcC-1gt91:
0.0		 2qqcB-1gt91:
13.55
2qqcC-1gt91:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 LEU 1 343
ASP 1 252
LEU 1 188
ARG 1 248
 None
 0.71A 2qqcA-1gt91:
0.0
2qqcF-1gt91:
0.0		 2qqcA-1gt91:
9.86
2qqcF-1gt91:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 ARG 1 248
LEU 1 343
ASP 1 252
LEU 1 188
 None
 0.73A 2qqcD-1gt91:
0.0
2qqcE-1gt91:
0.0		 2qqcD-1gt91:
13.55
2qqcE-1gt91:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 LEU 1 343
ASP 1 252
LEU 1 188
ARG 1 248
 None
 0.73A 2qqcG-1gt91:
0.0
2qqcJ-1gt91:
0.0		 2qqcG-1gt91:
9.86
2qqcJ-1gt91:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 LEU 1 343
ASP 1 252
LEU 1 188
ARG 1 248
 None
 0.68A 2qqcI-1gt91:
0.0
2qqcL-1gt91:
0.0		 2qqcI-1gt91:
9.86
2qqcL-1gt91:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 8 ARG 1 248
LEU 1 343
ASP 1 252
LEU 1 188
 None
 0.76A 2qqcH-1gt91:
0.0
2qqcK-1gt91:
0.0		 2qqcH-1gt91:
13.55
2qqcK-1gt91:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 LEU 1 343
ASP 1 252
LEU 1 188
ARG 1 248
 None
 0.73A 2qqdA-1gt91:
0.0
2qqdE-1gt91:
0.0		 2qqdA-1gt91:
10.14
2qqdE-1gt91:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 8 ARG 1 248
LEU 1 343
ASP 1 252
LEU 1 188
 None
 0.71A 2qqdB-1gt91:
0.0
2qqdC-1gt91:
0.0		 2qqdB-1gt91:
13.55
2qqdC-1gt91:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 9 LEU 1 195
ILE 1 317
ALA 1 254
GLU 1 312
GLY 1 348
 None
 1.20A 2v0mB-1gt91:
undetectable		 2v0mB-1gt91:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 10 PHE 1  17
ALA 1 286
ALA 1 285
THR 1 157
LEU 1 188
 None
 1.43A 2wuzA-1gt91:
undetectable		 2wuzA-1gt91:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 10 PHE 1  17
ALA 1 286
ALA 1 285
THR 1 157
LEU 1 188
 None
 1.43A 2wuzB-1gt91:
0.0		 2wuzB-1gt91:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		3 / 3 TYR 1  15
TYR 1 263
GLY 1 255
 None
 0.67A 3eteB-1gt91:
undetectable
3eteD-1gt91:
undetectable
3eteF-1gt91:
undetectable		 3eteB-1gt91:
21.63
3eteD-1gt91:
21.63
3eteF-1gt91:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 8 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.43A 4feuD-1gt91:
undetectable		 4feuD-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 11 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.41A 4feuB-1gt91:
0.0
4feuE-1gt91:
0.0		 4feuB-1gt91:
24.04
4feuE-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 10 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.38A 4fevA-1gt91:
0.0		 4fevA-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 7 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.42A 4fevB-1gt91:
undetectable		 4fevB-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 11 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.35A 4fevE-1gt91:
0.0		 4fevE-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 11 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.36A 4fewA-1gt91:
0.0
4fewD-1gt91:
0.0		 4fewA-1gt91:
24.04
4fewD-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 11 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.33A 4fewE-1gt91:
0.0
4fewF-1gt91:
0.0		 4fewE-1gt91:
24.04
4fewF-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 10 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.38A 4fexD-1gt91:
0.0		 4fexD-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 11 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.34A 4gkhC-1gt91:
0.0
4gkhD-1gt91:
0.0		 4gkhC-1gt91:
24.04
4gkhD-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 10 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.31A 4gkhG-1gt91:
0.0
4gkhH-1gt91:
0.0		 4gkhG-1gt91:
24.04
4gkhH-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 11 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.34A 4gkhI-1gt91:
undetectable
4gkhJ-1gt91:
0.0		 4gkhI-1gt91:
24.04
4gkhJ-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 6 ASP 1 268
ASN 1  66
ASP 1  38
GLU 1  39
 None
 1.34A 4gkhJ-1gt91:
0.0		 4gkhJ-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 10 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.30A 4gkhK-1gt91:
0.0
4gkhL-1gt91:
0.0		 4gkhK-1gt91:
24.04
4gkhL-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 11 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.31A 4gkiC-1gt91:
0.0
4gkiD-1gt91:
0.0		 4gkiC-1gt91:
24.04
4gkiD-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 10 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.31A 4gkiG-1gt91:
0.0
4gkiH-1gt91:
0.0		 4gkiG-1gt91:
24.04
4gkiH-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 9 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.39A 4gkiK-1gt91:
0.0		 4gkiK-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 ASP 1 268
ASN 1  66
GLU 1  32
ASP 1  38
GLU 1  39
 None
 1.35A 4gkiK-1gt91:
0.0
4gkiL-1gt91:
0.0		 4gkiK-1gt91:
24.04
4gkiL-1gt91:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 SER 1 278
GLY 1  36
ASP 1  76
GLY 1  34
 None
 0.92A 4koeA-1gt91:
undetectable
4koeB-1gt91:
undetectable
4koeD-1gt91:
undetectable		 4koeA-1gt91:
20.52
4koeB-1gt91:
20.52
4koeD-1gt91:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 11 ILE 1 111
PHE 1 107
LEU 1 108
ALA 1 105
VAL 1 158
 None
 1.12A 4nqaA-1gt91:
undetectable		 4nqaA-1gt91:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 ASN 1 292
GLY 1 296
LEU 1 356
THR 1 157
ILE 1 124
 None
 1.09A 4p6xA-1gt91:
undetectable		 4p6xA-1gt91:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 ASN 1 292
GLY 1 296
LEU 1 356
THR 1 157
ILE 1 124
 None
 1.05A 4p6xE-1gt91:
undetectable		 4p6xE-1gt91:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 5 LEU 1 195
TYR 1  15
ALA 1 254
ILE 1 317
 None
 1.19A 4y03B-1gt91:
undetectable		 4y03B-1gt91:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 7 GLY 1  36
ASP 1  76
GLY 1  34
SER 1 278
 None
 0.89A 4z53A-1gt91:
undetectable
4z53B-1gt91:
undetectable		 4z53A-1gt91:
18.94
4z53B-1gt91:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 9 LEU 1 306
LEU 1 355
ILE 1 291
PRO 1  18
LEU 1 352
 None
 1.41A 5g48B-1gt91:
0.0		 5g48B-1gt91:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		3 / 3 THR 1 103
ASP 1 104
ALA 1 105
 None
 0.06A 5g5gB-1gt91:
0.0		 5g5gB-1gt91:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 6 PRO 1  54
ALA 1 281
LEU 1 159
TYR 1  98
 None
 1.06A 5igiA-1gt91:
undetectable		 5igiA-1gt91:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		5 / 12 ASP 1 173
SER 1 140
LEU 1  33
PHE 1 107
ALA 1 183
 None
 1.11A 5vc0A-1gt91:
undetectable		 5vc0A-1gt91:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 1gt9 KUMAMOLYSIN
(Bacillus
subtilis) 		4 / 5 ASN 1 241
GLY 1 131
HIS 1 177
ASP 1 173
 None
 0.91A 6gh9A-1gt91:
0.0		 6gh9A-1gt91:
12.77