SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gu3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 1gu3 ENDOGLUCANASE C
(Cellulomonas
fimi) 		4 / 5 ARG A  75
ALA A 126
ASP A  90
GLY A  79
 BGC  A 601 (-3.0A)
BGC  A 602 ( 4.5A)
None
None
 0.90A 1e7bA-1gu3A:
undetectable		 1e7bA-1gu3A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 1gu3 ENDOGLUCANASE C
(Cellulomonas
fimi) 		4 / 5 ARG A  75
ALA A 126
ASP A  90
GLY A  79
 BGC  A 601 (-3.0A)
BGC  A 602 ( 4.5A)
None
None
 0.96A 1e7cA-1gu3A:
undetectable		 1e7cA-1gu3A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 1gu3 ENDOGLUCANASE C
(Cellulomonas
fimi) 		5 / 12 GLY A  20
ALA A 126
GLN A 128
GLN A 124
GLY A 130
 None
BGC  A 602 ( 4.5A)
BGC  A 601 (-3.6A)
BGC  A 602 ( 2.8A)
None
 0.83A 2pkkA-1gu3A:
undetectable		 2pkkA-1gu3A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 1gu3 ENDOGLUCANASE C
(Cellulomonas
fimi) 		5 / 12 GLY A  20
ALA A 126
GLN A 128
GLN A 124
GLY A 130
 None
BGC  A 602 ( 4.5A)
BGC  A 601 (-3.6A)
BGC  A 602 ( 2.8A)
None
 0.83A 2pkmA-1gu3A:
undetectable		 2pkmA-1gu3A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1gu3 ENDOGLUCANASE C
(Cellulomonas
fimi) 		5 / 12 TYR A 112
PHE A 106
LEU A  77
ARG A 100
VAL A 102
 None
 1.24A 3fpjB-1gu3A:
undetectable		 3fpjB-1gu3A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1gu3 ENDOGLUCANASE C
(Cellulomonas
fimi) 		4 / 6 GLY A  12
GLU A  14
ASP A  26
ASP A  11
 None
 0.85A 4uckB-1gu3A:
undetectable		 4uckB-1gu3A:
17.04