SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 11 CYH A 199
ALA A 169
VAL A 187
ARG A 190
ALA A 211
 None
 1.20A 1n4hA-1gudA:
0.0		 1n4hA-1gudA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 ALA A  80
TYR A  86
ILE A  23
ALA A  64
LEU A  90
 None
 1.11A 2plwA-1gudA:
undetectable		 2plwA-1gudA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 8 ASP A 227
ASP A 202
ASP A 113
TYR A 198
 None
 1.20A 3havA-1gudA:
0.0		 3havA-1gudA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 141
ALA A 143
GLU A 149
ALA A 200
ASP A 174
 None
 1.27A 3nmuA-1gudA:
0.0
3nmuF-1gudA:
2.7		 3nmuA-1gudA:
22.77
3nmuF-1gudA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 188
ASN A 191
ALA A 137
ILE A 139
ILE A 197
 None
 1.10A 4o2bB-1gudA:
4.1		 4o2bB-1gudA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 THR A 203
ASN A  13
PHE A  15
 None
 0.75A 4pd9A-1gudA:
0.0		 4pd9A-1gudA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 9 LEU A 257
GLY A  62
VAL A  34
SER A  33
VAL A  32
 None
 1.03A 4qd3A-1gudA:
3.5		 4qd3A-1gudA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 5 ARG A 152
GLY A 148
GLU A 149
SER A 283
 None
 1.12A 4z3oA-1gudA:
3.5
4z3oB-1gudA:
3.7		 4z3oA-1gudA:
18.75
4z3oB-1gudA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 LEU A   8
ILE A  23
GLY A  22
VAL A 110
ILE A 252
 None
 1.02A 5ycnA-1gudA:
0.0		 5ycnA-1gudA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 ALA A 119
VAL A 224
TYR A 198
 None
 0.71A 5zmqH-1gudA:
0.0		 5zmqH-1gudA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 PHE A 124
ALA A 205
ALA A 209
THR A 218
LEU A 222
 None
 1.15A 6aybA-1gudA:
undetectable		 6aybA-1gudA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 9 LEU A  90
MET A  19
VAL A   6
LEU A  11
ILE A  36
 None
 1.39A 6fdyU-1gudA:
0.0		 6fdyU-1gudA:
19.74