SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		4 / 7 TYR A 132
ASP A 101
GLU A  97
PHE A 136
 None
 1.45A 1b2iA-1gulA:
0.0		 1b2iA-1gulA:
14.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		4 / 8 TYR A   9
GLY A  14
ARG A  15
PHE A 220
 None
 0.63A 1gsfC-1gulA:
32.8		 1gsfC-1gulA:
53.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		5 / 12 ILE A 159
GLN A 162
ARG A  15
ARG A  69
GLU A  97
 None
 1.47A 1ki7B-1gulA:
undetectable		 1ki7B-1gulA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		4 / 8 LEU A 148
ILE A 139
LEU A  91
ILE A  92
 None
 0.77A 2azxA-1gulA:
undetectable		 2azxA-1gulA:
18.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		4 / 8 TYR A   9
GLY A  14
ARG A  15
PHE A 111
 None
 0.54A 2vctA-1gulA:
33.5		 2vctA-1gulA:
54.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		4 / 8 TYR A   9
GLY A  14
ARG A  15
PHE A 111
 None
 0.56A 2vctB-1gulA:
33.4		 2vctB-1gulA:
54.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		4 / 7 TYR A   9
GLY A  14
ARG A  15
PHE A 111
 None
 0.57A 2vctD-1gulA:
33.3		 2vctD-1gulA:
54.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		4 / 5 TYR A 212
LEU A 106
GLU A  17
VAL A 158
 None
 1.27A 4nkvA-1gulA:
0.0		 4nkvA-1gulA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		5 / 9 VAL A  96
LEU A  72
ASP A  77
VAL A 158
ILE A 159
 None
 1.09A 5om2A-1gulA:
undetectable
5om2B-1gulA:
undetectable		 5om2A-1gulA:
16.28
5om2B-1gulA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens) 		4 / 6 ALA A 156
LEU A 160
TYR A 184
SER A 154
 None
 1.09A 5phhA-1gulA:
undetectable		 5phhA-1gulA:
19.89