SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
4 / 6 LYS A  18
LEU A  16
ALA A  23
SER A  37
None
0.86A 1ictB-1gutA:
undetectable
1ictB-1gutA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
5 / 12 SER A  37
VAL A  13
LEU A  27
LEU A  47
LEU A  55
None
1.01A 1mx1F-1gutA:
undetectable
1mx1F-1gutA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
4 / 7 LYS A  18
LEU A  16
ALA A  23
SER A  37
None
0.66A 1tyrB-1gutA:
undetectable
1tyrB-1gutA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
4 / 7 LYS A  18
LEU A  16
ALA A  23
SER A  37
None
0.95A 3cfqA-1gutA:
undetectable
3cfqB-1gutA:
undetectable
3cfqA-1gutA:
21.67
3cfqB-1gutA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
4 / 7 LYS A  18
LEU A  16
ALA A  23
SER A  37
None
0.95A 3d2tA-1gutA:
undetectable
3d2tA-1gutA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
4 / 6 LYS A  18
LEU A  16
ALA A  23
SER A  37
None
0.89A 4d7bB-1gutA:
undetectable
4d7bB-1gutA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
4 / 7 LYS A  18
LEU A  16
ALA A  23
SER A  37
None
0.82A 4d7bA-1gutA:
undetectable
4d7bA-1gutA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
3 / 3 LYS A  18
LEU A  16
ALA A  23
None
0.71A 4iizA-1gutA:
0.0
4iizA-1gutA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
4 / 6 LYS A  18
LEU A  16
ALA A  23
SER A  37
None
0.95A 4ikiB-1gutA:
undetectable
4ikiB-1gutA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
4 / 6 LYS A  18
LEU A  16
ALA A  23
SER A  37
None
1.01A 5bojA-1gutA:
undetectable
5bojA-1gutA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum)
4 / 6 LYS A  18
LEU A  16
ALA A  23
SER A  37
None
0.94A 5l4iA-1gutA:
undetectable
5l4iA-1gutA:
18.18