SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gv3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		5 / 10 ASP A  30
GLN A 122
ARG A 233
ILE A  29
GLY A  27
 None
 1.48A 1fohC-1gv3A:
undetectable		 1fohC-1gv3A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY A 111
LEU A  93
LEU A  96
VAL A  99
ALA A  77
 None
 0.94A 1gseA-1gv3A:
0.0		 1gseA-1gv3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY A 111
LEU A  93
LEU A  96
VAL A  99
ALA A  77
 None
 0.98A 1gseB-1gv3A:
0.0		 1gseB-1gv3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 8 GLY A  27
ILE A  26
ILE A 230
ILE A 123
 None
 0.71A 1hshD-1gv3A:
undetectable		 1hshD-1gv3A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		5 / 10 ASP A  30
GLN A 122
ARG A 233
ILE A  29
GLY A  27
 None
 1.46A 1pn0C-1gv3A:
0.0		 1pn0C-1gv3A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		5 / 10 ASP A  30
GLN A 122
ARG A 233
ILE A  29
GLY A  27
 None
 1.47A 1pn0D-1gv3A:
0.0		 1pn0D-1gv3A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 6 HIS A  62
ASP A  48
TYR A  45
HIS A  66
 MN  A1238 (-3.4A)
None
None
None
 1.50A 2dysA-1gv3A:
0.9
2dysC-1gv3A:
1.0		 2dysA-1gv3A:
17.70
2dysC-1gv3A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 6 HIS A  62
ASP A  48
TYR A  45
HIS A  66
 MN  A1238 (-3.4A)
None
None
None
 1.48A 2dysN-1gv3A:
0.8
2dysP-1gv3A:
1.0		 2dysN-1gv3A:
17.70
2dysP-1gv3A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 6 HIS A  62
ASP A  48
TYR A  45
HIS A  66
 MN  A1238 (-3.4A)
None
None
None
 1.48A 2eimA-1gv3A:
0.7
2eimC-1gv3A:
1.0		 2eimA-1gv3A:
17.70
2eimC-1gv3A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 6 HIS A  62
ASP A  48
TYR A  45
HIS A  66
 MN  A1238 (-3.4A)
None
None
None
 1.50A 2einA-1gv3A:
0.9
2einC-1gv3A:
1.0		 2einA-1gv3A:
17.70
2einC-1gv3A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		3 / 3 GLY A 158
ASP A 160
SER A 181
 None
 0.72A 2qhfA-1gv3A:
undetectable		 2qhfA-1gv3A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 6 HIS A  62
ASP A  48
TYR A  45
HIS A  66
 MN  A1238 (-3.4A)
None
None
None
 1.50A 2zxwN-1gv3A:
0.8
2zxwP-1gv3A:
1.0		 2zxwN-1gv3A:
17.70
2zxwP-1gv3A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 7 HIS A  62
ASP A  48
TYR A  45
HIS A  66
 MN  A1238 (-3.4A)
None
None
None
 1.49A 3abkN-1gv3A:
0.4
3abkP-1gv3A:
1.0		 3abkN-1gv3A:
17.70
3abkP-1gv3A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 8 ILE A 119
PRO A 132
VAL A 225
TRP A 227
 None
 1.31A 4f4dB-1gv3A:
undetectable		 4f4dB-1gv3A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 7 ALA A  38
THR A  35
VAL A 107
HIS A 114
 None
 1.01A 5ecnA-1gv3A:
undetectable		 5ecnA-1gv3A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 5 SER A 181
VAL A 167
GLY A 158
ALA A 157
 None
 0.97A 5k50A-1gv3A:
0.0		 5k50A-1gv3A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		3 / 3 THR A 182
PRO A 173
ARG A 171
 None
 0.82A 5nd7B-1gv3A:
undetectable		 5nd7B-1gv3A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 7 THR A  58
HIS A  62
PHE A 120
MET A 124
 None
MN  A1238 (-3.4A)
None
None
 1.37A 5u6mA-1gv3A:
undetectable		 5u6mA-1gv3A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		4 / 7 THR A  58
HIS A  62
PHE A 120
MET A 124
 None
MN  A1238 (-3.4A)
None
None
 1.36A 5u6mB-1gv3A:
undetectable		 5u6mB-1gv3A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		3 / 3 THR A 106
ALA A  77
LYS A  79
 None
 0.62A 6fgcA-1gv3A:
undetectable		 6fgcA-1gv3A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 1gv3 MANGANESE SUPEROXIDE
DISMUTASE
(Nostoc
sp.
PCC
7120) 		3 / 3 THR A 106
ALA A  77
LYS A  79
 None
 0.61A 6fgdA-1gv3A:
undetectable		 6fgdA-1gv3A:
18.45