SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 1gvc OVOTRANSFERRIN
(Anas
platyrhynchos) 		5 / 12 GLU A 223
GLU A 226
VAL A 100
TYR A 227
VAL A 216
 None
 1.45A 2rguA-1gvcA:
undetectable		 2rguA-1gvcA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 1gvc OVOTRANSFERRIN
(Anas
platyrhynchos) 		5 / 11 GLU A 223
GLU A 226
VAL A 100
TYR A 227
VAL A 216
 None
 1.45A 2rguB-1gvcA:
undetectable		 2rguB-1gvcA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 1gvc OVOTRANSFERRIN
(Anas
platyrhynchos) 		5 / 12 GLU A 223
GLU A 226
VAL A 100
TYR A 227
VAL A 216
 None
 1.47A 3bjmB-1gvcA:
undetectable		 3bjmB-1gvcA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1gvc OVOTRANSFERRIN
(Anas
platyrhynchos) 		5 / 12 GLU A 223
GLU A 226
VAL A 100
TYR A 227
VAL A 216
 None
 1.49A 3g0bC-1gvcA:
undetectable		 3g0bC-1gvcA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1gvc OVOTRANSFERRIN
(Anas
platyrhynchos) 		5 / 12 ALA A  97
ILE A 141
TRP A 128
PHE A 210
HIS A 119
 None
 1.25A 3wenA-1gvcA:
undetectable		 3wenA-1gvcA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1gvc OVOTRANSFERRIN
(Anas
platyrhynchos) 		5 / 12 ALA A  97
ILE A 141
TRP A 128
PHE A 210
HIS A 119
 None
 1.25A 3weoA-1gvcA:
undetectable		 3weoA-1gvcA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1gvc OVOTRANSFERRIN
(Anas
platyrhynchos) 		4 / 4 PRO A 131
LEU A 135
ILE A 141
ARG A 113
 None
 1.25A 4f4dA-1gvcA:
undetectable		 4f4dA-1gvcA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1gvc OVOTRANSFERRIN
(Anas
platyrhynchos) 		4 / 8 PHE A 158
VAL A 208
ASP A 207
ALA A  99
 None
 0.89A 4m48A-1gvcA:
undetectable		 4m48A-1gvcA:
13.36