SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gw1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 8 ALA A 131
HIS A  77
ILE A 138
THR A  82
 None
 0.77A 1c9sU-1gw1A:
undetectable
1c9sV-1gw1A:
undetectable		 1c9sU-1gw1A:
14.09
1c9sV-1gw1A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 7 SER A  95
THR A  97
ASN A  99
ASN A 362
 None
 0.92A 1dssG-1gw1A:
undetectable		 1dssG-1gw1A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 8 SER A  95
THR A  97
ASN A  99
ASN A 362
 None
 0.91A 1dssR-1gw1A:
undetectable		 1dssR-1gw1A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 8 THR A  82
ALA A 131
HIS A  77
ILE A 138
 None
 0.80A 1gtnA-1gw1A:
undetectable
1gtnB-1gw1A:
undetectable		 1gtnA-1gw1A:
14.09
1gtnB-1gw1A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		3 / 3 TRP A 294
PHE A 295
TRP A 337
 None
 1.44A 1r15C-1gw1A:
1.3		 1r15C-1gw1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		3 / 3 TRP A 294
PHE A 295
TRP A 337
 None
 1.43A 1r15F-1gw1A:
1.7		 1r15F-1gw1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		3 / 3 TRP A 294
PHE A 295
TRP A 337
 None
 1.44A 1r15G-1gw1A:
1.8		 1r15G-1gw1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		3 / 3 TRP A 294
PHE A 295
TRP A 337
 None
 1.44A 1r15H-1gw1A:
2.2		 1r15H-1gw1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		5 / 12 ILE A 354
ALA A 303
ASP A 348
THR A 284
ILE A 318
 None
 1.11A 1re7A-1gw1A:
undetectable		 1re7A-1gw1A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 8 ALA A 131
HIS A  77
ILE A 138
THR A  82
 None
 0.80A 1utdJ-1gw1A:
undetectable
1utdK-1gw1A:
undetectable		 1utdJ-1gw1A:
14.09
1utdK-1gw1A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 7 TYR A 108
GLY A  92
THR A  81
ASP A  91
 None
 1.05A 2g70A-1gw1A:
undetectable		 2g70A-1gw1A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 7 TYR A 108
GLY A  92
THR A  81
ASP A  91
 None
 1.07A 2g70B-1gw1A:
undetectable		 2g70B-1gw1A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		5 / 12 ILE A 328
PHE A  75
ALA A 100
PHE A 396
TYR A 338
 None
 0.99A 3apwB-1gw1A:
0.0		 3apwB-1gw1A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		5 / 8 SER A  95
THR A  97
ASN A  99
HIS A  77
ASN A 362
 None
 1.02A 3dmtC-1gw1A:
undetectable		 3dmtC-1gw1A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		5 / 12 PHE A 356
MET A  65
VAL A 107
ILE A 137
TYR A 415
 None
 1.42A 3elzA-1gw1A:
undetectable		 3elzA-1gw1A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		3 / 3 TYR A 184
ASP A 163
ASP A 150
 None
 0.61A 3r24A-1gw1A:
undetectable		 3r24A-1gw1A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 6 MET A 308
LEU A 280
PRO A 272
PRO A 256
 None
 1.30A 3vkxA-1gw1A:
undetectable		 3vkxA-1gw1A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		6 / 12 ILE A 354
ALA A 303
ALA A 347
THR A 284
LEU A 341
ILE A 318
 None
 1.29A 4kjjA-1gw1A:
undetectable		 4kjjA-1gw1A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		3 / 3 HIS A 143
TRP A 156
SER A 141
 MAF  A1427 ( 3.9A)
None
None
 1.13A 4lrhD-1gw1A:
undetectable		 4lrhD-1gw1A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		6 / 12 ILE A 354
ALA A 303
ALA A 347
THR A 284
LEU A 341
ILE A 318
 None
 1.24A 4pssA-1gw1A:
undetectable		 4pssA-1gw1A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 8 LEU A 345
ASN A 301
ALA A 302
VAL A 305
 None
 0.48A 4zbqA-1gw1A:
undetectable		 4zbqA-1gw1A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		5 / 11 LEU A 241
GLY A 246
SER A 237
GLU A 190
ALA A 189
 None
 1.03A 5o96G-1gw1A:
undetectable		 5o96G-1gw1A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 307
ALA A 309
PRO A 316
GLU A 353
 None
 1.03A 5odqA-1gw1A:
undetectable		 5odqA-1gw1A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 6 GLU A 320
ARG A 208
ALA A 212
TYR A 285
 MAF  A1427 (-2.2A)
ZN  A1424 (-2.2A)
None
MBF  A1428 ( 3.9A)
 1.08A 5phhA-1gw1A:
undetectable		 5phhA-1gw1A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 8 TRP A 220
TRP A 219
TYR A 184
THR A 112
 None
 1.40A 5tzoC-1gw1A:
undetectable		 5tzoC-1gw1A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 5 ASN A 257
ASP A 283
SER A 255
ARG A 208
 None
ZN  A1424 (-2.2A)
ZN  A1424 ( 4.2A)
ZN  A1424 (-2.2A)
 1.40A 5w4zA-1gw1A:
10.6		 5w4zA-1gw1A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 8 HIS A  79
THR A  82
TRP A 191
PHE A 250
 None
 1.20A 5yj1k-1gw1A:
0.0
5yj1t-1gw1A:
0.0		 5yj1k-1gw1A:
14.89
5yj1t-1gw1A:
14.89