SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gy7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 1gy7 NUCLEAR TRANSPORT
FACTOR 2
(Saccharomyces
cerevisiae) 		4 / 6 THR A  13
GLN A 101
PHE A  99
HIS A  64
 None
 1.38A 1tt0A-1gy7A:
undetectable		 1tt0A-1gy7A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 1gy7 NUCLEAR TRANSPORT
FACTOR 2
(Saccharomyces
cerevisiae) 		4 / 6 THR A  13
GLN A 101
PHE A  99
HIS A  64
 None
 1.38A 1tt0B-1gy7A:
undetectable		 1tt0B-1gy7A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 1gy7 NUCLEAR TRANSPORT
FACTOR 2
(Saccharomyces
cerevisiae) 		4 / 6 THR A  13
GLN A 101
PHE A  99
HIS A  64
 None
 1.39A 1tt0C-1gy7A:
undetectable		 1tt0C-1gy7A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 1gy7 NUCLEAR TRANSPORT
FACTOR 2
(Saccharomyces
cerevisiae) 		4 / 6 THR A  13
GLN A 101
PHE A  99
HIS A  64
 None
 1.38A 1tt0D-1gy7A:
undetectable		 1tt0D-1gy7A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1gy7 NUCLEAR TRANSPORT
FACTOR 2
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 123
GLU A  40
LEU A  88
PHE A 119
 None
 1.32A 4twdF-1gy7A:
undetectable
4twdG-1gy7A:
0.0		 4twdF-1gy7A:
18.49
4twdG-1gy7A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1gy7 NUCLEAR TRANSPORT
FACTOR 2
(Saccharomyces
cerevisiae) 		5 / 8 GLY A  28
VAL A 114
ILE A  50
LEU A  54
ILE A  84
 None
 1.02A 5vkqB-1gy7A:
undetectable
5vkqC-1gy7A:
undetectable		 5vkqB-1gy7A:
5.69
5vkqC-1gy7A:
5.69