SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gyd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
4 / 5 LYS B 203
ALA B 202
ASP B 270
GLY B 275
None
1.13A 1e7cA-1gydB:
undetectable
1e7cA-1gydB:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
4 / 6 LEU B 107
TRP B 138
PHE B  51
VAL B  40
None
1.30A 1ibgH-1gydB:
0.0
1ibgH-1gydB:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
4 / 8 GLY B  56
SER B 110
ASP B 158
ASP B  38
None
0.89A 1m4iA-1gydB:
0.0
1m4iA-1gydB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
4 / 5 LEU B 189
VAL B 123
TYR B 106
THR B 190
None
1.50A 1nw3A-1gydB:
undetectable
1nw3A-1gydB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 LEU B 278
HIS B 250
LYS B 281
None
0.94A 1y7iA-1gydB:
undetectable
1y7iA-1gydB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
4 / 5 LEU B 321
LEU B 251
LEU B 278
LEU B 305
None
0.93A 1yajD-1gydB:
undetectable
1yajD-1gydB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
4 / 5 SER B 147
ASP B 152
PRO B 149
SER B 119
None
1.34A 2hdnA-1gydB:
0.0
2hdnB-1gydB:
undetectable
2hdnD-1gydB:
undetectable
2hdnA-1gydB:
9.21
2hdnB-1gydB:
21.17
2hdnD-1gydB:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
4 / 5 SER B 119
SER B 147
ASP B 152
PRO B 149
None
1.33A 2hdnB-1gydB:
undetectable
2hdnC-1gydB:
0.0
2hdnD-1gydB:
undetectable
2hdnB-1gydB:
21.17
2hdnC-1gydB:
9.21
2hdnD-1gydB:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 12 LEU B 323
LEU B 279
LEU B 278
GLY B 290
LEU B 305
None
1.05A 2ouzA-1gydB:
undetectable
2ouzA-1gydB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 11 ASN B 272
GLY B 178
ILE B 220
LYS B 181
LEU B 180
None
1.37A 3bexC-1gydB:
undetectable
3bexD-1gydB:
undetectable
3bexC-1gydB:
21.60
3bexD-1gydB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 10 LYS B 181
LEU B 180
ASN B 272
GLY B 178
ILE B 220
None
1.35A 3bexC-1gydB:
undetectable
3bexD-1gydB:
undetectable
3bexC-1gydB:
21.60
3bexD-1gydB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 10 ASN B 272
GLY B 178
ILE B 220
LYS B 181
LEU B 180
None
1.37A 3bexE-1gydB:
undetectable
3bexF-1gydB:
undetectable
3bexE-1gydB:
21.60
3bexF-1gydB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 11 ASN B 272
GLY B 178
ILE B 220
LYS B 181
LEU B 180
None
1.39A 3bf1A-1gydB:
undetectable
3bf1B-1gydB:
undetectable
3bf1A-1gydB:
21.60
3bf1B-1gydB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 11 ASN B 272
GLY B 178
ILE B 220
LYS B 181
LEU B 180
None
1.40A 3bf1C-1gydB:
0.1
3bf1D-1gydB:
undetectable
3bf1C-1gydB:
21.60
3bf1D-1gydB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 11 LYS B 181
LEU B 180
ASN B 272
GLY B 178
ILE B 220
None
1.38A 3bf1C-1gydB:
undetectable
3bf1D-1gydB:
undetectable
3bf1C-1gydB:
21.60
3bf1D-1gydB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 11 ASN B 272
GLY B 178
ILE B 220
LYS B 181
LEU B 180
None
1.38A 3bf1E-1gydB:
undetectable
3bf1F-1gydB:
undetectable
3bf1E-1gydB:
21.60
3bf1F-1gydB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 11 LYS B 181
LEU B 180
ASN B 272
GLY B 178
ILE B 220
None
1.35A 3bf1E-1gydB:
undetectable
3bf1F-1gydB:
0.0
3bf1E-1gydB:
21.60
3bf1F-1gydB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 12 GLY B 239
GLY B 288
SER B 247
ALA B 236
HIS B 291
None
1.14A 3ou6B-1gydB:
undetectable
3ou6B-1gydB:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 12 GLY B 239
GLY B 288
SER B 247
ALA B 236
HIS B 291
None
1.14A 3ou7B-1gydB:
undetectable
3ou7B-1gydB:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 12 ILE B 145
LEU B 182
PHE B 183
ILE B 161
LEU B 185
None
1.13A 3ql0A-1gydB:
undetectable
3ql0A-1gydB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 ARG B  84
THR B  80
TRP B  81
None
1.11A 4d7hA-1gydB:
0.0
4d7hA-1gydB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 PRO B  79
TYR B 109
GLY B  56
None
0.67A 4g2zA-1gydB:
undetectable
4g2zA-1gydB:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 12 ALA B  95
ILE B 145
ASP B 140
GLY B 122
GLY B 142
None
1.27A 4hfpB-1gydB:
undetectable
4hfpB-1gydB:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 ARG B  84
THR B  80
TRP B  81
None
1.12A 4uglA-1gydB:
0.0
4uglA-1gydB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 12 LEU B 338
SER B 340
LEU B 289
LEU B 303
ILE B 280
None
1.13A 4x1gA-1gydB:
0.0
4x1gA-1gydB:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 12 ILE B 145
LEU B 182
PHE B 183
ILE B 161
LEU B 185
None
1.14A 4x5hA-1gydB:
undetectable
4x5hA-1gydB:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 ARG B  84
THR B  80
TRP B  81
None
1.13A 5g6cA-1gydB:
0.0
5g6cA-1gydB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 TRP B 177
ILE B 157
SER B 112
None
1.03A 5gqbA-1gydB:
undetectable
5gqbA-1gydB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 LEU B 321
LEU B 323
TRP B 325
None
0.87A 5nwuA-1gydB:
0.0
5nwuA-1gydB:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 ILE B 280
VAL B 333
PRO B 331
None
0.66A 5uunA-1gydB:
undetectable
5uunA-1gydB:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
5 / 7 ALA B 120
ILE B  57
PHE B  89
LEU B  93
ILE B 161
None
1.47A 6b5vA-1gydB:
undetectable
6b5vB-1gydB:
undetectable
6b5vA-1gydB:
14.81
6b5vB-1gydB:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 SER B 147
SER B 119
ALA B 215
None
0.66A 6dwnC-1gydB:
undetectable
6dwnC-1gydB:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 LEU B 107
GLY B 122
PHE B  89
None
0.67A 6exiC-1gydB:
undetectable
6exiC-1gydB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
4 / 6 ILE B 225
TYR B 263
LEU B 182
SER B 172
None
1.26A 6f6jA-1gydB:
0.0
6f6jA-1gydB:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
4 / 6 LEU B 153
ASP B 211
ARG B 206
GLN B 150
None
1.25A 6g31J-1gydB:
undetectable
6g31J-1gydB:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus)
3 / 3 ILE B  57
THR B  58
PRO B  96
None
0.65A 6ncsA-1gydB:
undetectable
6ncsA-1gydB:
22.73