SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gz7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 8 GLY A 123
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.77A 1ax9A-1gz7A:
41.6
1ax9A-1gz7A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 8 GLY A 124
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.91A 1ax9A-1gz7A:
41.6
1ax9A-1gz7A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 122
GLY A 123
GLY A 124
SER A 209
PHE A 345
HIS A 449
None
0.35A 1dx6A-1gz7A:
42.7
1dx6A-1gz7A:
30.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 7 ILE A 453
TYR A 467
PHE A 471
PHE A 434
None
1.04A 1e71M-1gz7A:
1.1
1e71M-1gz7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 7 ILE A 453
TYR A 467
PHE A 471
PHE A 434
None
1.02A 1e72M-1gz7A:
0.7
1e72M-1gz7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 PHE A 526
TYR A 320
LEU A 377
LEU A 409
ASP A 412
None
1.29A 1e7wA-1gz7A:
1.5
1e7wA-1gz7A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.28A 1jhoA-1gz7A:
2.8
1jhoA-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 8 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.30A 1jhqA-1gz7A:
undetectable
1jhqA-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.29A 1jhrA-1gz7A:
1.4
1jhrA-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 8 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.29A 1jhvA-1gz7A:
undetectable
1jhvA-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.28A 1jhyA-1gz7A:
2.6
1jhyA-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.25A 1l4nA-1gz7A:
1.4
1l4nA-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.25A 1l5kA-1gz7A:
1.3
1l5kA-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.26A 1l5lA-1gz7A:
undetectable
1l5lA-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.24A 1l5mA-1gz7A:
1.3
1l5mA-1gz7A:
20.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 8 GLY A 123
GLU A 208
SER A 209
HIS A 449
None
0.47A 1maaD-1gz7A:
37.7
1maaD-1gz7A:
32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 8 GLY A 124
GLU A 208
SER A 209
HIS A 449
None
0.73A 1maaD-1gz7A:
37.7
1maaD-1gz7A:
32.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 4 HIS A 180
ALA A 177
PHE A  38
GLY A 175
GOL  A1538 (-3.9A)
None
None
None
1.22A 1mj2B-1gz7A:
undetectable
1mj2B-1gz7A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 4 HIS A 180
ALA A 177
PHE A  38
GLY A 175
GOL  A1538 (-3.9A)
None
None
None
1.30A 1mj2D-1gz7A:
undetectable
1mj2D-1gz7A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 4 HIS A 180
ALA A 177
PHE A  38
GLY A 175
GOL  A1538 (-3.9A)
None
None
None
1.24A 1mjoB-1gz7A:
undetectable
1mjoB-1gz7A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 4 HIS A 180
ALA A 177
PHE A  38
GLY A 175
GOL  A1538 (-3.9A)
None
None
None
1.19A 1mjoA-1gz7A:
undetectable
1mjoA-1gz7A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 4 HIS A 180
ALA A 177
PHE A  38
GLY A 175
GOL  A1538 (-3.9A)
None
None
None
1.25A 1mjoD-1gz7A:
undetectable
1mjoD-1gz7A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 6 LEU A  78
LEU A 445
ILE A  86
GLU A  70
None
1.10A 1mt1A-1gz7A:
0.0
1mt1F-1gz7A:
0.0
1mt1A-1gz7A:
9.58
1mt1F-1gz7A:
11.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLY A 122
GLY A 123
SER A 209
VAL A 296
HIS A 449
None
1.11A 1mx1A-1gz7A:
40.1
1mx1A-1gz7A:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 122
GLY A 123
LEU A 127
PHE A 345
HIS A 449
None
0.92A 1mx1D-1gz7A:
40.3
1mx1D-1gz7A:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 122
GLY A 123
SER A 209
VAL A 296
LEU A 127
HIS A 449
None
1.32A 1mx1D-1gz7A:
40.3
1mx1D-1gz7A:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 123
GLY A 124
SER A 209
LEU A 297
PHE A 415
None
0.85A 1mx1D-1gz7A:
40.3
1mx1D-1gz7A:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 123
GLY A 124
SER A 209
PHE A 415
HIS A 449
None
0.59A 1mx1D-1gz7A:
40.3
1mx1D-1gz7A:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 122
GLY A 123
LEU A 127
PHE A 345
HIS A 449
None
0.79A 1mx1F-1gz7A:
39.8
1mx1F-1gz7A:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 122
GLY A 123
SER A 209
VAL A 296
HIS A 449
None
1.02A 1mx1F-1gz7A:
39.8
1mx1F-1gz7A:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 123
GLY A 124
SER A 209
LEU A 304
PHE A 415
HIS A 449
None
0.79A 1mx1F-1gz7A:
39.8
1mx1F-1gz7A:
31.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 LEU A 127
GLY A 122
ALA A 210
LEU A 302
LEU A 304
None
1.06A 1nr6A-1gz7A:
undetectable
1nr6A-1gz7A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLY A 242
GLY A 450
ASP A 452
ILE A 453
HIS A 449
None
0.84A 1pg2A-1gz7A:
2.2
1pg2A-1gz7A:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
7 / 12 GLY A 122
GLY A 123
GLY A 124
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.45A 1qtiA-1gz7A:
41.5
1qtiA-1gz7A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
7 / 12 GLY A 122
GLY A 123
GLY A 124
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.74A 1qtiA-1gz7A:
41.5
1qtiA-1gz7A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 ASP A 457
GLY A 211
GLY A 122
SER A 209
PHE A  87
HIS A 449
None
1.45A 1w6rA-1gz7A:
42.7
1w6rA-1gz7A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 122
GLY A 123
GLY A 124
SER A 209
PHE A 345
HIS A 449
None
0.38A 1w6rA-1gz7A:
42.7
1w6rA-1gz7A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 122
GLY A 123
GLY A 124
SER A 209
PHE A 345
HIS A 449
None
0.77A 1w6rA-1gz7A:
42.7
1w6rA-1gz7A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 11 GLY A 123
GLY A 124
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.44A 1w76A-1gz7A:
41.3
1w76A-1gz7A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 10 GLY A 122
GLY A 123
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.36A 1w76B-1gz7A:
41.3
1w76B-1gz7A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 10 GLY A 123
GLY A 124
SER A 209
PHE A 345
HIS A 449
None
1.03A 1w76B-1gz7A:
41.3
1w76B-1gz7A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 10 GLY A 124
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.81A 1w76B-1gz7A:
41.3
1w76B-1gz7A:
30.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 6 PHE A  87
VAL A 296
LEU A 302
PHE A  69
None
1.06A 1wrlB-1gz7A:
2.3
1wrlB-1gz7A:
10.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_A_CTXA1_1
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 122
GLY A 123
SER A 209
LEU A 127
LEU A 297
HIS A 449
None
1.21A 1ya4A-1gz7A:
40.0
1ya4A-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_A_CTXA1_1
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 123
GLY A 124
SER A 209
LEU A 297
HIS A 449
None
0.77A 1ya4A-1gz7A:
40.0
1ya4A-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_B_CTXB2_1
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 122
GLY A 123
VAL A 296
LEU A 127
LEU A 297
HIS A 449
None
1.15A 1ya4B-1gz7A:
36.5
1ya4B-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_B_CTXB2_1
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 123
SER A 209
VAL A 296
LEU A 127
LEU A 297
HIS A 449
None
1.21A 1ya4B-1gz7A:
36.5
1ya4B-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_C_CTXC3_1
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
7 / 12 GLY A 122
GLY A 123
SER A 209
VAL A 296
LEU A 127
LEU A 297
HIS A 449
None
1.27A 1ya4C-1gz7A:
39.9
1ya4C-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_C_CTXC3_1
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 122
LEU A 127
LEU A 344
LEU A 304
HIS A 449
None
0.98A 1ya4C-1gz7A:
39.9
1ya4C-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_C_CTXC3_1
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 123
GLY A 124
SER A 209
LEU A 344
HIS A 449
None
0.67A 1ya4C-1gz7A:
39.9
1ya4C-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 8 GLY A 122
GLY A 123
GLY A 124
SER A 209
ALA A 210
HIS A 449
None
0.40A 1yajC-1gz7A:
39.5
1yajC-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 8 GLY A 211
GLY A 122
GLY A 123
SER A 209
ALA A 210
HIS A 449
None
1.16A 1yajC-1gz7A:
39.5
1yajC-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 8 GLY A 211
GLY A 122
SER A 209
ALA A 210
LEU A 127
HIS A 449
None
1.30A 1yajC-1gz7A:
39.5
1yajC-1gz7A:
31.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 6 GLY A 124
SER A 209
LEU A 304
HIS A 449
None
0.96A 1yajF-1gz7A:
39.0
1yajF-1gz7A:
31.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 6 TYR A 467
SER A 436
THR A 447
ASN A 451
None
1.10A 1yvpB-1gz7A:
undetectable
1yvpB-1gz7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 SER A 365
VAL A 534
LEU A 304
LEU A 410
TYR A 361
None
1.16A 2a15A-1gz7A:
0.0
2a15A-1gz7A:
14.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 122
GLY A 123
SER A 209
ALA A 210
HIS A 449
None
0.92A 2aceA-1gz7A:
43.0
2aceA-1gz7A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 9 GLY A 123
GLY A 124
SER A 209
ALA A 210
PHE A 345
HIS A 449
None
0.87A 2aceA-1gz7A:
43.0
2aceA-1gz7A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 7 GLY A 123
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.81A 2ackA-1gz7A:
43.0
2ackA-1gz7A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 7 GLY A 124
SER A 209
PHE A 345
HIS A 449
None
0.89A 2ackA-1gz7A:
43.0
2ackA-1gz7A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 8 GLU A 208
PHE A 345
HIS A 449
GLY A 450
None
0.19A 2ha4A-1gz7A:
41.1
2ha4A-1gz7A:
32.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 8 GLY A 123
GLY A 124
ALA A 210
PHE A 345
HIS A 449
None
0.94A 2ha4A-1gz7A:
41.1
2ha4A-1gz7A:
32.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 7 GLY A 123
GLY A 124
ALA A 210
HIS A 449
None
0.36A 2ha4B-1gz7A:
42.0
2ha4B-1gz7A:
32.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 6 PHE A 474
GLN A 456
ASN A 468
LEU A 439
None
1.18A 2nyrA-1gz7A:
0.4
2nyrA-1gz7A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 7 GLY A 224
GLY A 429
PHE A 422
PHE A 216
None
0.96A 2qwxA-1gz7A:
2.4
2qwxB-1gz7A:
1.8
2qwxA-1gz7A:
18.73
2qwxB-1gz7A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 ILE A 169
GLY A 255
GLY A 252
ASP A 248
TYR A 259
None
1.19A 2zw9A-1gz7A:
3.1
2zw9A-1gz7A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 6 VAL A 139
GLN A 456
GLY A 463
LEU A 510
None
1.01A 3bjwE-1gz7A:
undetectable
3bjwE-1gz7A:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 342
LEU A 409
LEU A 413
SER A 348
SER A 301
None
1.06A 3g2oA-1gz7A:
undetectable
3g2oA-1gz7A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 342
LEU A 409
LEU A 413
SER A 348
SER A 301
None
1.03A 3g2oB-1gz7A:
undetectable
3g2oB-1gz7A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLN A 456
SER A 214
TRP A 119
GLY A 207
GLY A 211
None
1.17A 3gy3A-1gz7A:
undetectable
3gy3A-1gz7A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 8 HIS A 449
LEU A 347
ILE A  86
VAL A  81
LEU A 445
None
1.40A 3kp6A-1gz7A:
undetectable
3kp6B-1gz7A:
undetectable
3kp6A-1gz7A:
15.94
3kp6B-1gz7A:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_A_BEZA999_0
(CHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 7 GLY A 122
GLY A 123
SER A 209
PHE A 415
HIS A 449
None
1.41A 3o9mA-1gz7A:
42.3
3o9mA-1gz7A:
30.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_A_BEZA999_0
(CHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 7 GLY A 123
GLY A 124
SER A 209
LEU A 302
PHE A 415
HIS A 449
None
0.64A 3o9mA-1gz7A:
42.3
3o9mA-1gz7A:
30.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_B_BEZB999_0
(CHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 6 GLY A 123
GLY A 124
SER A 209
LEU A 302
HIS A 449
None
0.72A 3o9mB-1gz7A:
42.3
3o9mB-1gz7A:
30.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 10 ALA A 470
ILE A 238
ALA A 237
THR A 215
VAL A 152
None
1.18A 3r9cA-1gz7A:
undetectable
3r9cA-1gz7A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 ALA A 210
GLY A 122
ALA A 159
LEU A 302
TYR A 306
None
1.25A 3rc0A-1gz7A:
0.0
3rc0A-1gz7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 ALA A 414
LEU A 409
GLY A 342
HIS A 449
LEU A 435
None
1.34A 3tm4A-1gz7A:
undetectable
3tm4A-1gz7A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 6 TYR A 467
GLN A 240
ASP A 457
GLN A 137
None
1.25A 4azvA-1gz7A:
1.7
4azvA-1gz7A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 ASP A 337
HIS A 449
GLY A 411
LEU A 344
GLY A 450
None
1.23A 4blvB-1gz7A:
1.8
4blvB-1gz7A:
19.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 122
GLY A 123
GLY A 124
SER A 209
PHE A 345
HIS A 449
None
0.32A 4ey6A-1gz7A:
41.7
4ey6A-1gz7A:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
6 / 12 GLY A 122
GLY A 123
GLY A 124
SER A 209
PHE A 345
HIS A 449
None
0.85A 4ey6A-1gz7A:
41.7
4ey6A-1gz7A:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
7 / 12 GLY A 122
GLY A 123
GLY A 124
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.31A 4ey6B-1gz7A:
38.2
4ey6B-1gz7A:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
7 / 12 GLY A 122
GLY A 123
GLY A 124
GLU A 208
SER A 209
PHE A 345
HIS A 449
None
0.82A 4ey6B-1gz7A:
38.2
4ey6B-1gz7A:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLY A 123
GLU A 208
SER A 209
HIS A 449
GLY A 450
None
0.71A 4ey7A-1gz7A:
41.7
4ey7A-1gz7A:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLY A 124
GLU A 208
SER A 209
HIS A 449
GLY A 450
None
0.96A 4ey7A-1gz7A:
41.7
4ey7A-1gz7A:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLY A 123
GLU A 208
SER A 209
HIS A 449
GLY A 450
None
0.73A 4ey7B-1gz7A:
41.4
4ey7B-1gz7A:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLY A 124
GLU A 208
SER A 209
HIS A 449
GLY A 450
None
0.97A 4ey7B-1gz7A:
41.4
4ey7B-1gz7A:
31.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLN A  83
ILE A 454
GLY A 461
GLY A 463
ASN A 468
None
1.47A 4fglA-1gz7A:
undetectable
4fglB-1gz7A:
undetectable
4fglA-1gz7A:
18.84
4fglB-1gz7A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 7 GLU A 341
ASP A 452
GLN A 338
ILE A  86
None
1.15A 4ii8A-1gz7A:
undetectable
4ii8A-1gz7A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 107
GLY A 113
LEU A 114
ARG A 109
GLY A 197
None
1.31A 4kqiA-1gz7A:
2.4
4kqiA-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
4 / 5 LEU A 127
GLY A 128
ILE A  86
GLN A  88
None
1.17A 4ma8C-1gz7A:
1.0
4ma8C-1gz7A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 ASP A 392
PHE A 517
GLY A 446
ASP A 412
THR A 416
None
1.18A 4mm4A-1gz7A:
0.0
4mm4A-1gz7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 PRO A  65
VAL A 296
ALA A 298
PHE A  87
GLY A  67
None
None
NAG  A1536 ( 4.6A)
None
None
1.12A 4mm5A-1gz7A:
undetectable
4mm5A-1gz7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 PRO A  65
VAL A 296
ALA A 298
PHE A  87
GLY A  67
None
None
NAG  A1536 ( 4.6A)
None
None
1.22A 4mmaA-1gz7A:
0.1
4mmaA-1gz7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 PRO A  65
VAL A 296
ALA A 298
PHE A  87
GLY A  67
None
None
NAG  A1536 ( 4.6A)
None
None
1.04A 4mmbA-1gz7A:
undetectable
4mmbA-1gz7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 10 PRO A  65
VAL A 296
ALA A 298
PHE A  87
GLY A  67
None
None
NAG  A1536 ( 4.6A)
None
None
1.09A 4mmdA-1gz7A:
0.8
4mmdA-1gz7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 PRO A  65
VAL A 296
ALA A 298
PHE A  87
GLY A  67
None
None
NAG  A1536 ( 4.6A)
None
None
1.10A 4mmdB-1gz7A:
1.0
4mmdB-1gz7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
1gz7 LIPASE 2
(Diutina
rugosa)
3 / 3 PRO A  65
LEU A 297
HIS A 449
None
0.57A 4pevA-1gz7A:
2.4
4pevA-1gz7A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 TYR A 361
LEU A 297
PHE A  87
GLY A 123
LEU A 304
None
1.31A 4ze1A-1gz7A:
0.0
4ze1A-1gz7A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 10 GLY A 124
LEU A 127
GLN A 456
PHE A 133
LEU A 297
None
1.30A 5fhzC-1gz7A:
0.1
5fhzC-1gz7A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)
1gz7 LIPASE 2
(Diutina
rugosa)
3 / 3 THR A 354
ASP A 355
ALA A 356
None
0.00A 5g5gB-1gz7A:
0.0
5g5gB-1gz7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)
1gz7 LIPASE 2
(Diutina
rugosa)
3 / 3 ILE A 466
ILE A 238
MET A 503
None
0.67A 5i9yA-1gz7A:
undetectable
5i9yA-1gz7A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLU A 341
LEU A 344
ASP A 452
LEU A 442
ALA A  77
None
0.93A 5kc4E-1gz7A:
undetectable
5kc4E-1gz7A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 GLY A 122
GLY A 128
VAL A  89
ILE A 120
ALA A 210
None
1.06A 5x7fA-1gz7A:
undetectable
5x7fA-1gz7A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)
1gz7 LIPASE 2
(Diutina
rugosa)
3 / 3 ASP A 412
PHE A 517
ARG A 419
None
0.92A 5yw0A-1gz7A:
0.0
5yw0A-1gz7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)
1gz7 LIPASE 2
(Diutina
rugosa)
3 / 3 ASP A 412
PHE A 517
ARG A 420
None
1.11A 5yw0A-1gz7A:
0.0
5yw0A-1gz7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 12 SER A 241
VAL A  81
GLY A 123
ALA A 210
PHE A 345
None
1.18A 6bqgA-1gz7A:
undetectable
6bqgA-1gz7A:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLY A 124
SER A 209
SER A 301
PHE A 415
HIS A 449
None
0.87A 6qgbA-1gz7A:
10.3
6qgbA-1gz7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 10 GLY A 124
SER A 209
SER A 301
PHE A 415
HIS A 449
None
0.87A 6qgbB-1gz7A:
9.8
6qgbB-1gz7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_C_BEZC701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 9 GLY A 124
SER A 209
SER A 301
PHE A 415
HIS A 449
None
0.88A 6qgbC-1gz7A:
3.2
6qgbC-1gz7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 10 GLY A 124
SER A 209
SER A 301
PHE A 415
HIS A 449
None
0.87A 6qgbD-1gz7A:
2.6
6qgbD-1gz7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 11 GLY A 124
SER A 209
SER A 301
PHE A 415
HIS A 449
None
0.85A 6qgbE-1gz7A:
10.8
6qgbE-1gz7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 10 GLY A 124
SER A 209
SER A 301
PHE A 415
HIS A 449
None
0.86A 6qgbF-1gz7A:
8.7
6qgbF-1gz7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_B_FFOB403_0
(THYMIDYLATE SYNTHASE)
1gz7 LIPASE 2
(Diutina
rugosa)
5 / 10 PHE A 121
ILE A 120
LEU A 219
LEU A 118
MET A 186
None
1.25A 6r2eB-1gz7A:
0.0
6r2eB-1gz7A:
20.65