SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gze'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 1gze MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		5 / 12 LEU A 135
ALA A 133
ILE A 239
ILE A 189
GLY A 129
 None
 0.93A 1qknA-1gzeA:
undetectable		 1qknA-1gzeA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QLT_B_ACTB601_0
(VANILLYL-ALCOHOL
OXIDASE)		 1gze MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 5 TYR A 134
ILE A 239
TYR A 223
ARG A 167
 None
 1.41A 1qltB-1gzeA:
0.0		 1qltB-1gzeA:
18.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1gze MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 7 ARG A 128
SER A 174
PHE A 183
GLU A 214
 None
 1.17A 2c8aA-1gzeA:
33.2		 2c8aA-1gzeA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1gze MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 7 ARG A 128
GLY A 129
SER A 174
GLU A 214
 None
 0.46A 2c8aB-1gzeA:
33.7		 2c8aB-1gzeA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1gze MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 6 ARG A 128
SER A 174
PHE A 183
GLU A 214
 None
 1.24A 2c8aC-1gzeA:
33.6		 2c8aC-1gzeA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1gze MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 7 ARG A 128
GLY A 129
SER A 174
GLU A 214
 None
 0.50A 2c8aD-1gzeA:
33.6		 2c8aD-1gzeA:
99.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1gze MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 8 SER A 181
ASN A 179
MET A 178
GLY A 211
 None
 1.03A 4af0A-1gzeA:
undetectable		 4af0A-1gzeA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 1gze MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		3 / 3 ILE A 188
PRO A 187
ILE A 237
 None
 0.40A 5hw8F-1gzeA:
0.0		 5hw8F-1gzeA:
16.67