SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1gzs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1gzs SOPE
(Salmonella
enterica) 		5 / 12 ILE B 231
ALA B 147
ALA B 167
LEU B 141
ILE B 144
 None
 1.16A 1g5yB-1gzsB:
0.0		 1g5yB-1gzsB:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 1gzs SOPE
(Salmonella
enterica) 		4 / 8 GLY B 145
GLU B 146
ALA B 147
ILE B 231
 None
 0.83A 2dtjA-1gzsB:
undetectable
2dtjB-1gzsB:
0.6		 2dtjA-1gzsB:
22.95
2dtjB-1gzsB:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 1gzs SOPE
(Salmonella
enterica) 		4 / 8 LEU B 212
ARG B  97
GLY B  98
ALA B 100
 None
 0.88A 2xfsA-1gzsB:
0.0		 2xfsA-1gzsB:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 1gzs SOPE
(Salmonella
enterica) 		4 / 8 LEU B 212
ARG B  97
GLY B  98
ALA B 100
 None
 0.88A 2xh9A-1gzsB:
0.0		 2xh9A-1gzsB:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1gzs SOPE
(Salmonella
enterica) 		5 / 10 GLU B 208
ARG B  97
LEU B 153
ILE B 114
MET B 218
 None
 1.32A 3adsA-1gzsB:
0.2		 3adsA-1gzsB:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1gzs SOPE
(Salmonella
enterica) 		5 / 12 ALA B 210
GLN B 225
ALA B 117
ILE B 114
GLN B 223
 None
 1.21A 4r38B-1gzsB:
undetectable		 4r38B-1gzsB:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1gzs SOPE
(Salmonella
enterica) 		5 / 12 ALA B 210
GLN B 225
ALA B 117
ILE B 114
GLN B 223
 None
 1.23A 4r38D-1gzsB:
undetectable		 4r38D-1gzsB:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1gzs SOPE
(Salmonella
enterica) 		4 / 4 SER B  99
ALA B 100
GLN B 109
THR B 110
 None
 1.23A 5n0sA-1gzsB:
undetectable		 5n0sA-1gzsB:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1gzs SOPE
(Salmonella
enterica) 		4 / 4 SER B  99
ALA B 100
GLN B 109
THR B 110
 None
 1.22A 5n0wA-1gzsB:
undetectable		 5n0wA-1gzsB:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1gzs SOPE
(Salmonella
enterica) 		4 / 5 SER B  99
ALA B 100
GLN B 109
THR B 110
 None
 1.23A 5n0wB-1gzsB:
undetectable		 5n0wB-1gzsB:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 1gzs SOPE
(Salmonella
enterica) 		5 / 11 ASN B 170
THR B 220
PHE B 213
ILE B  96
VAL B 209
 None
 1.45A 6hcoA-1gzsB:
0.8
6hcoB-1gzsB:
0.8		 6hcoA-1gzsB:
13.75
6hcoB-1gzsB:
13.75