SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h09'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		4 / 6 TYR A 127
ASP A  95
PHE A  61
ARG A  63
 None
 1.48A 2a3bB-1h09A:
5.2		 2a3bB-1h09A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8O_A_OINA1317_1
(CHOLINE-BINDING
PROTEIN F)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		4 / 4 TRP A 223
TRP A 230
TYR A 252
MET A 260
 None
 0.36A 2x8oA-1h09A:
8.6		 2x8oA-1h09A:
29.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8O_A_OINA1317_1
(CHOLINE-BINDING
PROTEIN F)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		4 / 4 TRP A 244
TRP A 251
TYR A 272
MET A 280
 None
 0.25A 2x8oA-1h09A:
8.6		 2x8oA-1h09A:
29.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8P_A_OINA1313_1
(CHOLINE-BINDING
PROTEIN F)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		4 / 4 TRP A 223
LYS A 225
TRP A 230
TYR A 252
 None
 1.32A 2x8pA-1h09A:
10.5		 2x8pA-1h09A:
29.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8P_A_OINA1313_1
(CHOLINE-BINDING
PROTEIN F)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		4 / 4 TRP A 244
LYS A 246
TRP A 251
TYR A 272
 None
 0.45A 2x8pA-1h09A:
10.5		 2x8pA-1h09A:
29.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O0M_A_ACTA146_0
(HIT FAMILY PROTEIN)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		4 / 4 ASP A  67
GLU A  72
GLU A  70
ARG A  73
 None
 1.41A 3o0mA-1h09A:
0.0		 3o0mA-1h09A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		4 / 6 GLN A 175
GLN A  25
ILE A  22
SER A 177
 None
 1.14A 3peoG-1h09A:
0.0		 3peoG-1h09A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		5 / 9 LEU A  89
ILE A 185
LEU A 187
ILE A 171
ILE A 150
 None
 1.25A 3zosB-1h09A:
undetectable		 3zosB-1h09A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		4 / 8 ARG A  73
GLU A  70
GLU A  72
ARG A 110
 None
 1.16A 4bqfB-1h09A:
2.2		 4bqfB-1h09A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		3 / 3 PHE A  61
TYR A 127
TYR A 125
 None
 1.05A 4ffwA-1h09A:
2.8		 4ffwA-1h09A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		5 / 12 ASP A  95
ARG A  63
ASN A 156
TYR A 153
ASP A  92
 None
 1.27A 5igzA-1h09A:
1.5		 5igzA-1h09A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		3 / 3 GLU A  94
ASP A  96
PRO A  97
 None
 0.70A 6berA-1h09A:
undetectable		 6berA-1h09A:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 1h09 LYSOZYME
(Streptococcus
virus
Cp1) 		3 / 3 ASP A 189
ASP A 275
ASN A 296
 None
 0.77A 6gngB-1h09A:
undetectable		 6gngB-1h09A:
20.29