SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1h0b CELLULASE
(Rhodothermus
marinus) 		5 / 11 LEU A  84
ALA A 123
VAL A 224
TYR A 198
LEU A  77
 None
 1.31A 1kt6A-1h0bA:
0.0		 1kt6A-1h0bA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 1h0b CELLULASE
(Rhodothermus
marinus) 		5 / 11 TYR A  19
GLY A  41
THR A  40
ALA A  15
VAL A 222
 None
 1.40A 2cojA-1h0bA:
undetectable
2cojB-1h0bA:
undetectable		 2cojA-1h0bA:
20.25
2cojB-1h0bA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1h0b CELLULASE
(Rhodothermus
marinus) 		5 / 11 ILE A  45
ALA A  48
GLY A 211
GLU A 210
GLY A  27
 None
 1.29A 4e47A-1h0bA:
undetectable		 4e47A-1h0bA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1h0b CELLULASE
(Rhodothermus
marinus) 		5 / 11 ILE A  45
ALA A  48
GLY A 211
GLU A 210
GLY A  27
 None
 1.29A 4e47B-1h0bA:
undetectable		 4e47B-1h0bA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 1h0b CELLULASE
(Rhodothermus
marinus) 		4 / 5 PHE A  43
PHE A 206
ILE A  45
GLY A 214
 None
 1.02A 4ejjC-1h0bA:
0.0		 4ejjC-1h0bA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1h0b CELLULASE
(Rhodothermus
marinus) 		5 / 11 ILE A  45
ALA A  48
GLY A 211
GLU A 210
GLY A  27
 None
 1.26A 4jdsA-1h0bA:
undetectable		 4jdsA-1h0bA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1h0b CELLULASE
(Rhodothermus
marinus) 		5 / 11 ILE A  45
ALA A  48
GLY A 211
GLU A 210
GLY A  27
 None
 1.27A 4jdsB-1h0bA:
undetectable		 4jdsB-1h0bA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1h0b CELLULASE
(Rhodothermus
marinus) 		5 / 11 ILE A  45
ALA A  48
GLY A 211
GLU A 210
GLY A  27
 None
 1.31A 4jdsC-1h0bA:
undetectable		 4jdsC-1h0bA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 1h0b CELLULASE
(Rhodothermus
marinus) 		5 / 11 LEU A   5
ASN A  23
GLY A 205
VAL A  36
ILE A  34
 None
 1.10A 5kr2B-1h0bA:
undetectable		 5kr2B-1h0bA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 1h0b CELLULASE
(Rhodothermus
marinus) 		5 / 9 LEU A   5
ASN A  23
GLY A 205
VAL A  36
ILE A  34
 None
 1.11A 5kr2D-1h0bA:
undetectable		 5kr2D-1h0bA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1h0b CELLULASE
(Rhodothermus
marinus) 		4 / 8 ASN A  42
PHE A  43
THR A  89
ILE A  62
 None
 0.99A 5nzxA-1h0bA:
undetectable		 5nzxA-1h0bA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1h0b CELLULASE
(Rhodothermus
marinus) 		4 / 7 ASN A  42
PHE A  43
THR A  89
ILE A  62
 None
 0.88A 5nzyA-1h0bA:
undetectable		 5nzyA-1h0bA:
20.99