SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h14'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 ALA A 105
ALA A  61
LYS A  60
GLU A  55
 None
 0.99A 1e7cA-1h14A:
0.0		 1e7cA-1h14A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 8 HIS A 204
TYR A 203
LEU A 236
SER A 232
 None
 1.06A 1i7zA-1h14A:
undetectable		 1i7zA-1h14A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.07A 1kifA-1h14A:
undetectable		 1kifA-1h14A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.07A 1kifB-1h14A:
undetectable		 1kifB-1h14A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.07A 1kifC-1h14A:
undetectable		 1kifC-1h14A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.07A 1kifD-1h14A:
undetectable		 1kifD-1h14A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.07A 1kifE-1h14A:
undetectable		 1kifE-1h14A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.07A 1kifF-1h14A:
undetectable		 1kifF-1h14A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.07A 1kifG-1h14A:
undetectable		 1kifG-1h14A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.07A 1kifH-1h14A:
undetectable		 1kifH-1h14A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.01A 1ve9A-1h14A:
undetectable		 1ve9A-1h14A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.09A 2du8G-1h14A:
undetectable		 2du8G-1h14A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A  53
TYR A  63
ILE A  75
GLY A 132
 None
 1.04A 2du8J-1h14A:
undetectable		 2du8J-1h14A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WB9_A_CYSA301_0
(GLUTATHIONE
TRANSFERASE SIGMA
CLASS)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 GLY A  79
ARG A  76
TYR A 380
TYR A 381
 None
 1.24A 2wb9A-1h14A:
3.3		 2wb9A-1h14A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 PHE A 399
PHE A 212
TYR A 209
ALA A  11
ALA A 150
 None
 1.23A 2x2nA-1h14A:
undetectable		 2x2nA-1h14A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 8 GLY A 161
ASN A 162
PHE A 404
TYR A 169
 None
 1.21A 3ccfA-1h14A:
undetectable		 3ccfA-1h14A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 4 PRO A  69
TYR A 378
GLY A 376
THR A 375
 None
 1.43A 3ib0A-1h14A:
0.0		 3ib0A-1h14A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2C_A_ACTA153_0
(N UTILIZATION
SUBSTANCE PROTEIN B)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 4 ASN A 382
GLY A 343
GLU A 342
LYS A 345
 None
 1.05A 3r2cA-1h14A:
1.6		 3r2cA-1h14A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		5 / 8 ASN A  44
GLY A  42
ASP A  38
PRO A 374
THR A 375
 None
 1.33A 4eyrB-1h14A:
0.0		 4eyrB-1h14A:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 7 MET A 175
GLU A 146
GLU A 147
TYR A 148
 None
 1.22A 4mj8C-1h14A:
0.0		 4mj8C-1h14A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		3 / 3 LEU A  20
MET A 390
TYR A  17
 None
 0.92A 4p6xG-1h14A:
0.6		 4p6xG-1h14A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 7 MET A 175
GLU A 146
GLU A 147
TYR A 148
 None
 1.03A 4r87I-1h14A:
0.0		 4r87I-1h14A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 4 TYR A 329
GLY A 311
SER A 314
LEU A 313
 None
 1.35A 5bphC-1h14A:
undetectable		 5bphC-1h14A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		3 / 3 MET A  40
GLN A  48
ARG A 379
 None
 0.96A 5ewzB-1h14A:
3.9		 5ewzB-1h14A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		3 / 3 PRO A 143
ILE A 173
SER A 192
 None
 0.68A 5fsaA-1h14A:
0.0		 5fsaA-1h14A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		3 / 3 ILE A 173
MET A 184
ASP A 221
 None
 0.80A 5h2uA-1h14A:
0.2		 5h2uA-1h14A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 7 PRO A 141
PHE A 191
SER A 202
ASN A 144
 None
 1.20A 5l1fC-1h14A:
undetectable		 5l1fC-1h14A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		3 / 3 MET A  40
GLN A  48
ARG A 379
 None
 0.96A 5m36A-1h14A:
3.7		 5m36A-1h14A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 ASN A 402
ASN A 401
LEU A 154
ASN A 155
GLY A 161
 None
 1.30A 6dwnA-1h14A:
undetectable		 6dwnA-1h14A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 8 VAL A  58
HIS A  62
TYR A 106
GLU A 165
 None
 1.24A 6gneB-1h14A:
undetectable		 6gneB-1h14A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 6 VAL A 285
ASN A 288
ILE A 205
GLU A 147
 None
 1.14A 6h7uA-1h14A:
undetectable		 6h7uA-1h14A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1h14 ENDO-1,4-BETA-XYLANA
SE
(Pseudoalteromona
s
haloplanktis) 		4 / 6 ASP A 281
TYR A 381
GLU A  78
GLU A 146
 None
 1.40A 6mn5C-1h14A:
0.0		 6mn5C-1h14A:
13.02