SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h21'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		5 / 9 GLY A  54
GLY A  45
PHE A  46
LEU A  72
GLY A  91
 None
 1.08A 1jhoA-1h21A:
undetectable		 1jhoA-1h21A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		5 / 8 GLY A  54
GLY A  45
PHE A  46
LEU A  72
GLY A  91
 None
 1.10A 1jhqA-1h21A:
undetectable		 1jhqA-1h21A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		5 / 9 GLY A  54
GLY A  45
PHE A  46
LEU A  72
GLY A  91
 None
 1.14A 1jhrA-1h21A:
undetectable		 1jhrA-1h21A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		5 / 9 GLY A  54
GLY A  45
PHE A  46
LEU A  72
GLY A  91
 None
 1.12A 1jhyA-1h21A:
undetectable		 1jhyA-1h21A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		5 / 9 GLY A  54
GLY A  45
PHE A  46
LEU A  72
GLY A  91
 None
 1.11A 1l4nA-1h21A:
undetectable		 1l4nA-1h21A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		5 / 9 GLY A  54
GLY A  45
PHE A  46
LEU A  72
GLY A  91
 None
 1.09A 1l5kA-1h21A:
undetectable		 1l5kA-1h21A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		5 / 9 GLY A  54
GLY A  45
PHE A  46
LEU A  72
GLY A  91
 None
 1.09A 1l5lA-1h21A:
undetectable		 1l5lA-1h21A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		5 / 9 GLY A  54
GLY A  45
PHE A  46
LEU A  72
GLY A  91
 None
 1.07A 1l5mA-1h21A:
undetectable		 1l5mA-1h21A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		4 / 7 LYS A 181
GLU A 184
ALA A 178
LEU A 121
 None
 1.10A 1sn0B-1h21A:
undetectable
1sn0D-1h21A:
undetectable		 1sn0B-1h21A:
21.03
1sn0D-1h21A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		5 / 12 LEU A 137
GLY A 132
ASP A  35
ALA A 130
ALA A 129
 None
 1.14A 2bm9A-1h21A:
undetectable		 2bm9A-1h21A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		3 / 3 GLY A  77
CYH A 147
CYH A  86
 None
 0.77A 5inzB-1h21A:
undetectable		 5inzB-1h21A:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		3 / 3 GLY A  78
CYH A 147
CYH A  86
 None
 0.80A 5inzB-1h21A:
undetectable		 5inzB-1h21A:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1h21 SPLIT-SORET
CYTOCHROME C
(Desulfovibrio
desulfuricans) 		4 / 8 GLY A  41
PHE A  46
GLY A 172
ALA A  48
 None
 0.69A 6hu9H-1h21A:
undetectable
6hu9e-1h21A:
undetectable		 6hu9H-1h21A:
16.67
6hu9e-1h21A:
20.16