SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1h29 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		3 / 3 LEU A 276
PRO A 277
LEU A 399
 None
HEC  A1112 (-3.7A)
None
 0.60A 2po5B-1h29A:
undetectable		 2po5B-1h29A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1h29 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		3 / 3 LEU A 276
PRO A 277
LEU A 399
 None
HEC  A1112 (-3.7A)
None
 0.58A 2po7B-1h29A:
undetectable		 2po7B-1h29A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 1h29 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		3 / 3 LEU A 276
PRO A 277
LEU A 399
 None
HEC  A1112 (-3.7A)
None
 0.46A 2qd5B-1h29A:
undetectable		 2qd5B-1h29A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1h29 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		4 / 6 PHE A 368
GLY A 521
ILE A 528
LEU A 456
 HEC  A1114 (-4.9A)
None
HEC  A1115 ( 4.5A)
HEC  A1111 ( 4.3A)
 0.69A 4o8fB-1h29A:
0.0		 4o8fB-1h29A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1h29 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		3 / 3 ALA A 397
ASN A 400
LEU A 401
 None
 0.48A 5i1nC-1h29A:
undetectable		 5i1nC-1h29A:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1h29 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		3 / 3 GLY A 396
THR A 328
PRO A 279
 None
 0.51A 5v5zA-1h29A:
0.0		 5v5zA-1h29A:
20.98