SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h2t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
5 / 12 VAL C 548
LEU C 551
ALA C 555
ALA C 565
LEU C 566
None
1.02A 1fk6A-1h2tC:
1.9
1fk6A-1h2tC:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 1k2rA-1h2tC:
0.0
1k2rB-1h2tC:
0.0
1k2rA-1h2tC:
19.45
1k2rB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.29A 1k2rA-1h2tC:
0.0
1k2rB-1h2tC:
0.0
1k2rA-1h2tC:
19.45
1k2rB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.35A 1k2sA-1h2tC:
0.0
1k2sB-1h2tC:
0.0
1k2sA-1h2tC:
19.45
1k2sB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 1k2tA-1h2tC:
0.0
1k2tB-1h2tC:
0.0
1k2tA-1h2tC:
19.45
1k2tB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.28A 1k2tA-1h2tC:
0.0
1k2tB-1h2tC:
0.0
1k2tA-1h2tC:
19.45
1k2tB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 1k2uA-1h2tC:
0.0
1k2uB-1h2tC:
0.0
1k2uA-1h2tC:
19.45
1k2uB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.39A 1lzxA-1h2tC:
0.0
1lzxB-1h2tC:
0.0
1lzxA-1h2tC:
19.45
1lzxB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 1lzxA-1h2tC:
0.0
1lzxB-1h2tC:
0.0
1lzxA-1h2tC:
19.45
1lzxB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.33A 1lzzA-1h2tC:
0.0
1lzzB-1h2tC:
0.0
1lzzA-1h2tC:
19.45
1lzzB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.36A 1lzzA-1h2tC:
0.0
1lzzB-1h2tC:
0.0
1lzzA-1h2tC:
19.45
1lzzB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 1m00A-1h2tC:
0.0
1m00B-1h2tC:
0.0
1m00A-1h2tC:
19.45
1m00B-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 1mmvA-1h2tC:
0.0
1mmvB-1h2tC:
0.0
1mmvA-1h2tC:
19.45
1mmvB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 1mmvA-1h2tC:
0.0
1mmvB-1h2tC:
0.0
1mmvA-1h2tC:
19.45
1mmvB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.39A 1mmwA-1h2tC:
0.0
1mmwB-1h2tC:
0.0
1mmwA-1h2tC:
19.45
1mmwB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 1mmwA-1h2tC:
0.0
1mmwB-1h2tC:
0.0
1mmwA-1h2tC:
19.45
1mmwB-1h2tC:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.25A 1om4A-1h2tC:
0.0
1om4B-1h2tC:
0.0
1om4A-1h2tC:
19.48
1om4B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.41A 1om4A-1h2tC:
0.0
1om4B-1h2tC:
0.0
1om4A-1h2tC:
19.48
1om4B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 1om5A-1h2tC:
0.0
1om5B-1h2tC:
0.0
1om5A-1h2tC:
19.51
1om5B-1h2tC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 1p6hA-1h2tC:
0.0
1p6hB-1h2tC:
0.0
1p6hA-1h2tC:
19.51
1p6hB-1h2tC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 1p6iA-1h2tC:
0.0
1p6iB-1h2tC:
0.0
1p6iA-1h2tC:
19.51
1p6iB-1h2tC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.40A 1p6iA-1h2tC:
0.0
1p6iB-1h2tC:
0.0
1p6iA-1h2tC:
19.51
1p6iB-1h2tC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.38A 1p6jA-1h2tC:
0.0
1p6jB-1h2tC:
0.0
1p6jA-1h2tC:
19.51
1p6jB-1h2tC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 1p6jA-1h2tC:
0.0
1p6jB-1h2tC:
0.0
1p6jA-1h2tC:
19.51
1p6jB-1h2tC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
3 / 3 VAL C 506
ALA C 505
HIS C 553
None
0.74A 1q23C-1h2tC:
undetectable
1q23C-1h2tC:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
3 / 3 VAL C 506
ALA C 505
HIS C 553
None
0.71A 1q23H-1h2tC:
0.0
1q23H-1h2tC:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
3 / 3 VAL C 506
ALA C 505
HIS C 553
None
0.71A 1q23J-1h2tC:
0.0
1q23J-1h2tC:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 HIS C 276
TYR C 282
ASN C 120
TYR C 121
None
1.04A 1qzrA-1h2tC:
undetectable
1qzrA-1h2tC:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 HIS C 276
TYR C 282
ASN C 120
TYR C 121
None
0.84A 1qzrB-1h2tC:
0.0
1qzrB-1h2tC:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
3 / 3 ASP C 403
LYS C 447
ARG C 450
None
1.09A 1ra8A-1h2tC:
undetectable
1ra8A-1h2tC:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.40A 1rs6A-1h2tC:
0.0
1rs6B-1h2tC:
0.0
1rs6A-1h2tC:
19.51
1rs6B-1h2tC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.32A 1rs7A-1h2tC:
0.0
1rs7B-1h2tC:
0.0
1rs7A-1h2tC:
19.51
1rs7B-1h2tC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.35A 1rs7A-1h2tC:
0.0
1rs7B-1h2tC:
0.0
1rs7A-1h2tC:
19.51
1rs7B-1h2tC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 ASN C 415
ARG C 746
ASN C 742
GLN C 749
None
1.41A 1t9uA-1h2tC:
2.7
1t9uA-1h2tC:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 5 PHE C 360
LEU C 402
PHE C 289
MET C 291
None
1.20A 1wrlC-1h2tC:
undetectable
1wrlC-1h2tC:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
LEU C 402
PHE C 289
MET C 291
None
1.17A 1wrlE-1h2tC:
undetectable
1wrlE-1h2tC:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.33A 1zvlA-1h2tC:
0.0
1zvlB-1h2tC:
0.0
1zvlA-1h2tC:
19.53
1zvlB-1h2tC:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 1zzqA-1h2tC:
0.0
1zzqB-1h2tC:
0.0
1zzqA-1h2tC:
19.53
1zzqB-1h2tC:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.22A 1zzqA-1h2tC:
0.0
1zzqB-1h2tC:
0.0
1zzqA-1h2tC:
19.53
1zzqB-1h2tC:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 TYR C 202
LEU C 203
GLU C 227
HIS C 210
None
0.91A 2bnnA-1h2tC:
undetectable
2bnnB-1h2tC:
undetectable
2bnnA-1h2tC:
14.58
2bnnB-1h2tC:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 2g6hA-1h2tC:
0.0
2g6hB-1h2tC:
0.0
2g6hA-1h2tC:
19.42
2g6hB-1h2tC:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 2g6kA-1h2tC:
0.0
2g6kB-1h2tC:
0.0
2g6kA-1h2tC:
19.42
2g6kB-1h2tC:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 2g6kA-1h2tC:
0.0
2g6kB-1h2tC:
0.0
2g6kA-1h2tC:
19.42
2g6kB-1h2tC:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 2g6mA-1h2tC:
0.0
2g6mB-1h2tC:
0.0
2g6mA-1h2tC:
19.42
2g6mB-1h2tC:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 2g6mA-1h2tC:
0.0
2g6mB-1h2tC:
0.0
2g6mA-1h2tC:
19.42
2g6mB-1h2tC:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
5 / 9 PHE C 173
ILE C 236
ASP C 230
LEU C 203
THR C 156
None
1.33A 2tsrD-1h2tC:
0.0
2tsrD-1h2tC:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
5 / 9 PHE C 292
LEU C 376
LEU C 391
ALA C 394
PHE C 356
None
1.18A 2vcvD-1h2tC:
2.2
2vcvD-1h2tC:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
5 / 9 PHE C 292
LEU C 376
LEU C 391
ALA C 394
PHE C 356
None
1.21A 2vcvE-1h2tC:
2.5
2vcvE-1h2tC:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
5 / 9 PHE C 292
LEU C 376
LEU C 391
ALA C 394
PHE C 356
None
1.21A 2vcvH-1h2tC:
2.4
2vcvH-1h2tC:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
5 / 9 PHE C 292
LEU C 376
LEU C 391
ALA C 394
PHE C 356
None
1.20A 2vcvI-1h2tC:
3.2
2vcvI-1h2tC:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.23A 3b3mA-1h2tC:
0.0
3b3mB-1h2tC:
0.0
3b3mA-1h2tC:
19.48
3b3mB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 3b3mA-1h2tC:
0.0
3b3mB-1h2tC:
0.0
3b3mA-1h2tC:
19.48
3b3mB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3b3nA-1h2tC:
0.0
3b3nB-1h2tC:
0.0
3b3nA-1h2tC:
19.48
3b3nB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 3b3nA-1h2tC:
0.0
3b3nB-1h2tC:
0.0
3b3nA-1h2tC:
19.48
3b3nB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3b3oA-1h2tC:
0.0
3b3oB-1h2tC:
0.0
3b3oA-1h2tC:
19.48
3b3oB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 3b3oA-1h2tC:
0.0
3b3oB-1h2tC:
0.0
3b3oA-1h2tC:
19.48
3b3oB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3b3pA-1h2tC:
0.0
3b3pB-1h2tC:
0.0
3b3pA-1h2tC:
19.48
3b3pB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 3b3pA-1h2tC:
0.0
3b3pB-1h2tC:
0.0
3b3pA-1h2tC:
19.48
3b3pB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 5 ILE C 544
THR C 550
PHE C 508
PHE C 569
None
1.34A 3em0A-1h2tC:
0.0
3em0A-1h2tC:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 3fc5A-1h2tC:
0.0
3fc5B-1h2tC:
0.0
3fc5A-1h2tC:
19.73
3fc5B-1h2tC:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.28A 3fc5A-1h2tC:
0.0
3fc5B-1h2tC:
0.0
3fc5A-1h2tC:
19.73
3fc5B-1h2tC:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 3hsnA-1h2tC:
0.0
3hsnB-1h2tC:
0.0
3hsnA-1h2tC:
19.48
3hsnB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.24A 3hsnA-1h2tC:
0.0
3hsnB-1h2tC:
0.0
3hsnA-1h2tC:
19.48
3hsnB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.30A 3hsoA-1h2tC:
0.0
3hsoB-1h2tC:
0.0
3hsoA-1h2tC:
19.48
3hsoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.31A 3hsoA-1h2tC:
0.0
3hsoB-1h2tC:
0.0
3hsoA-1h2tC:
19.48
3hsoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.35A 3hspA-1h2tC:
0.0
3hspB-1h2tC:
0.0
3hspA-1h2tC:
19.48
3hspB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.32A 3hspA-1h2tC:
0.0
3hspB-1h2tC:
0.0
3hspA-1h2tC:
19.48
3hspB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 4 GLY C 102
VAL C 105
GLY C  91
THR C  88
None
0.95A 3ib2A-1h2tC:
0.0
3ib2A-1h2tC:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.36A 3jt3A-1h2tC:
0.0
3jt3B-1h2tC:
0.0
3jt3A-1h2tC:
19.48
3jt3B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3jt4A-1h2tC:
0.0
3jt4B-1h2tC:
0.0
3jt4A-1h2tC:
19.48
3jt4B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 3jt4A-1h2tC:
0.0
3jt4B-1h2tC:
0.0
3jt4A-1h2tC:
19.48
3jt4B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3jt5A-1h2tC:
0.0
3jt5B-1h2tC:
0.0
3jt5A-1h2tC:
19.48
3jt5B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 3jt5A-1h2tC:
0.0
3jt5B-1h2tC:
0.0
3jt5A-1h2tC:
19.48
3jt5B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3jt6A-1h2tC:
0.0
3jt6B-1h2tC:
0.0
3jt6A-1h2tC:
19.48
3jt6B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.36A 3jt6A-1h2tC:
0.0
3jt6B-1h2tC:
0.0
3jt6A-1h2tC:
19.48
3jt6B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 3jt7A-1h2tC:
0.0
3jt7B-1h2tC:
0.0
3jt7A-1h2tC:
19.48
3jt7B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 3jt7A-1h2tC:
0.0
3jt7B-1h2tC:
0.0
3jt7A-1h2tC:
19.48
3jt7B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3jt8A-1h2tC:
0.0
3jt8B-1h2tC:
0.0
3jt8A-1h2tC:
19.48
3jt8B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.40A 3jt8A-1h2tC:
0.0
3jt8B-1h2tC:
0.0
3jt8A-1h2tC:
19.48
3jt8B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3jt9A-1h2tC:
0.0
3jt9B-1h2tC:
0.0
3jt9A-1h2tC:
19.48
3jt9B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.32A 3jt9A-1h2tC:
0.0
3jt9B-1h2tC:
0.0
3jt9A-1h2tC:
19.48
3jt9B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 3jtaA-1h2tC:
0.0
3jtaB-1h2tC:
0.0
3jtaA-1h2tC:
19.48
3jtaB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.30A 3jtaA-1h2tC:
0.0
3jtaB-1h2tC:
0.0
3jtaA-1h2tC:
19.48
3jtaB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3jwsA-1h2tC:
0.0
3jwsB-1h2tC:
0.0
3jwsA-1h2tC:
19.92
3jwsB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.24A 3jwsA-1h2tC:
0.0
3jwsB-1h2tC:
0.0
3jwsA-1h2tC:
19.92
3jwsB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 3jwtA-1h2tC:
0.0
3jwtB-1h2tC:
0.0
3jwtA-1h2tC:
19.92
3jwtB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.30A 3jwtA-1h2tC:
0.0
3jwtB-1h2tC:
0.0
3jwtA-1h2tC:
19.92
3jwtB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3jwuA-1h2tC:
0.0
3jwuB-1h2tC:
0.0
3jwuA-1h2tC:
19.92
3jwuB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 3jwuA-1h2tC:
0.0
3jwuB-1h2tC:
0.0
3jwuA-1h2tC:
19.92
3jwuB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3jwvA-1h2tC:
0.0
3jwvB-1h2tC:
0.0
3jwvA-1h2tC:
19.92
3jwvB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 3jwvA-1h2tC:
0.0
3jwvB-1h2tC:
0.0
3jwvA-1h2tC:
19.92
3jwvB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3jx0A-1h2tC:
0.0
3jx0B-1h2tC:
0.0
3jx0A-1h2tC:
19.59
3jx0B-1h2tC:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 3jx0A-1h2tC:
0.0
3jx0B-1h2tC:
0.0
3jx0A-1h2tC:
19.59
3jx0B-1h2tC:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3jx1A-1h2tC:
0.0
3jx1B-1h2tC:
0.0
3jx1A-1h2tC:
19.59
3jx1B-1h2tC:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 3jx1A-1h2tC:
0.0
3jx1B-1h2tC:
0.0
3jx1A-1h2tC:
19.59
3jx1B-1h2tC:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
5 / 8 HIS C 585
LEU C 576
VAL C 524
LEU C 521
VAL C 546
None
1.21A 3kp6A-1h2tC:
undetectable
3kp6B-1h2tC:
undetectable
3kp6A-1h2tC:
11.69
3kp6B-1h2tC:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.39A 3n2rA-1h2tC:
0.0
3n2rB-1h2tC:
0.0
3n2rA-1h2tC:
19.48
3n2rB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 3n2rA-1h2tC:
0.0
3n2rB-1h2tC:
0.0
3n2rA-1h2tC:
19.48
3n2rB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 3n5yA-1h2tC:
0.0
3n5yB-1h2tC:
0.0
3n5yA-1h2tC:
19.48
3n5yB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 3n5yA-1h2tC:
0.0
3n5yB-1h2tC:
0.0
3n5yA-1h2tC:
19.48
3n5yB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.30A 3n5zA-1h2tC:
0.0
3n5zB-1h2tC:
0.0
3n5zA-1h2tC:
19.48
3n5zB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 3n5zA-1h2tC:
0.0
3n5zB-1h2tC:
0.0
3n5zA-1h2tC:
19.48
3n5zB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.45A 3n65A-1h2tC:
0.0
3n65B-1h2tC:
0.0
3n65A-1h2tC:
19.48
3n65B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3nlkA-1h2tC:
0.0
3nlkB-1h2tC:
0.0
3nlkA-1h2tC:
19.92
3nlkB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 3nlkA-1h2tC:
0.0
3nlkB-1h2tC:
0.0
3nlkA-1h2tC:
19.92
3nlkB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3nlmA-1h2tC:
0.0
3nlmB-1h2tC:
0.0
3nlmA-1h2tC:
19.48
3nlmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 3nlmA-1h2tC:
0.0
3nlmB-1h2tC:
0.0
3nlmA-1h2tC:
19.48
3nlmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3nlnA-1h2tC:
0.0
3nlnB-1h2tC:
0.0
3nlnA-1h2tC:
19.92
3nlnB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3nloA-1h2tC:
0.0
3nloB-1h2tC:
0.0
3nloA-1h2tC:
19.92
3nloB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.23A 3nlvA-1h2tC:
0.0
3nlvB-1h2tC:
0.0
3nlvA-1h2tC:
19.48
3nlvB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 3nlvA-1h2tC:
0.0
3nlvB-1h2tC:
0.0
3nlvA-1h2tC:
19.48
3nlvB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 3nlwA-1h2tC:
0.0
3nlwB-1h2tC:
0.0
3nlwA-1h2tC:
19.48
3nlwB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3nlxA-1h2tC:
0.0
3nlxB-1h2tC:
0.0
3nlxA-1h2tC:
19.48
3nlxB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.27A 3nlxA-1h2tC:
0.0
3nlxB-1h2tC:
0.0
3nlxA-1h2tC:
19.48
3nlxB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 3nlyA-1h2tC:
0.0
3nlyB-1h2tC:
0.0
3nlyA-1h2tC:
19.48
3nlyB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 3nlzA-1h2tC:
0.0
3nlzB-1h2tC:
0.0
3nlzA-1h2tC:
19.48
3nlzB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.27A 3nlzA-1h2tC:
0.0
3nlzB-1h2tC:
0.0
3nlzA-1h2tC:
19.48
3nlzB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 3nm0A-1h2tC:
0.0
3nm0B-1h2tC:
0.0
3nm0A-1h2tC:
19.48
3nm0B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.42A 3nm0A-1h2tC:
0.0
3nm0B-1h2tC:
0.0
3nm0A-1h2tC:
19.48
3nm0B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3nnyA-1h2tC:
0.0
3nnyB-1h2tC:
0.0
3nnyA-1h2tC:
19.48
3nnyB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 3nnyA-1h2tC:
0.0
3nnyB-1h2tC:
0.0
3nnyA-1h2tC:
19.48
3nnyB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.21A 3nnzA-1h2tC:
0.0
3nnzB-1h2tC:
0.0
3nnzA-1h2tC:
19.48
3nnzB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.24A 3nnzA-1h2tC:
0.0
3nnzB-1h2tC:
0.0
3nnzA-1h2tC:
19.48
3nnzB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 3pneA-1h2tC:
0.0
3pneB-1h2tC:
0.0
3pneA-1h2tC:
19.48
3pneB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 3pneA-1h2tC:
0.0
3pneB-1h2tC:
0.0
3pneA-1h2tC:
19.48
3pneB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 3pnfA-1h2tC:
0.0
3pnfB-1h2tC:
0.0
3pnfA-1h2tC:
19.48
3pnfB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 3pnfA-1h2tC:
0.0
3pnfB-1h2tC:
0.0
3pnfA-1h2tC:
19.48
3pnfB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3pngA-1h2tC:
0.0
3pngB-1h2tC:
0.0
3pngA-1h2tC:
19.48
3pngB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 3pngA-1h2tC:
0.0
3pngB-1h2tC:
0.0
3pngA-1h2tC:
19.48
3pngB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 3q99A-1h2tC:
0.0
3q99B-1h2tC:
0.0
3q99A-1h2tC:
19.48
3q99B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.43A 3q99A-1h2tC:
0.0
3q99B-1h2tC:
0.0
3q99A-1h2tC:
19.48
3q99B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 3q9aA-1h2tC:
0.0
3q9aB-1h2tC:
0.0
3q9aA-1h2tC:
19.48
3q9aB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.36A 3q9aA-1h2tC:
0.0
3q9aB-1h2tC:
0.0
3q9aA-1h2tC:
19.48
3q9aB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 3rqjA-1h2tC:
0.0
3rqjB-1h2tC:
0.0
3rqjA-1h2tC:
19.48
3rqjB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.28A 3rqkA-1h2tC:
0.0
3rqkB-1h2tC:
0.0
3rqkA-1h2tC:
19.48
3rqkB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 3rqlA-1h2tC:
0.0
3rqlB-1h2tC:
0.0
3rqlA-1h2tC:
19.48
3rqlB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 3rqlA-1h2tC:
0.0
3rqlB-1h2tC:
0.0
3rqlA-1h2tC:
19.48
3rqlB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.25A 3rqmA-1h2tC:
0.0
3rqmB-1h2tC:
0.0
3rqmA-1h2tC:
19.48
3rqmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 3rqmA-1h2tC:
0.0
3rqmB-1h2tC:
0.0
3rqmA-1h2tC:
19.48
3rqmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 3rqnA-1h2tC:
0.0
3rqnB-1h2tC:
0.0
3rqnA-1h2tC:
19.48
3rqnB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 3rqnA-1h2tC:
0.0
3rqnB-1h2tC:
0.0
3rqnA-1h2tC:
19.48
3rqnB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 5 LEU C 229
ARG C 166
ARG C 206
ARG C 165
None
1.04A 3ticA-1h2tC:
undetectable
3ticA-1h2tC:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.38A 3tylA-1h2tC:
0.0
3tylB-1h2tC:
0.0
3tylA-1h2tC:
19.48
3tylB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 3tylA-1h2tC:
0.0
3tylB-1h2tC:
0.0
3tylA-1h2tC:
19.48
3tylB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.35A 3tymA-1h2tC:
0.0
3tymB-1h2tC:
0.0
3tymA-1h2tC:
19.48
3tymB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.28A 3tymA-1h2tC:
0.0
3tymB-1h2tC:
0.0
3tymA-1h2tC:
19.48
3tymB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.34A 3tynA-1h2tC:
0.0
3tynB-1h2tC:
0.0
3tynA-1h2tC:
19.48
3tynB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 3tynA-1h2tC:
0.0
3tynB-1h2tC:
0.0
3tynA-1h2tC:
19.48
3tynB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.39A 3tyoA-1h2tC:
0.0
3tyoB-1h2tC:
0.0
3tyoA-1h2tC:
19.48
3tyoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 3tyoA-1h2tC:
0.0
3tyoB-1h2tC:
0.0
3tyoA-1h2tC:
19.48
3tyoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.40A 3ufoA-1h2tC:
0.0
3ufoB-1h2tC:
0.0
3ufoA-1h2tC:
19.48
3ufoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.42A 3ufpA-1h2tC:
0.0
3ufpB-1h2tC:
0.0
3ufpA-1h2tC:
19.48
3ufpB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.42A 3ufqA-1h2tC:
0.0
3ufqB-1h2tC:
0.0
3ufqA-1h2tC:
19.48
3ufqB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.43A 3ufrA-1h2tC:
0.0
3ufrB-1h2tC:
0.0
3ufrA-1h2tC:
19.48
3ufrB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.42A 3ufsA-1h2tC:
0.0
3ufsB-1h2tC:
0.0
3ufsA-1h2tC:
19.48
3ufsB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 3uftA-1h2tC:
0.0
3uftB-1h2tC:
0.0
3uftA-1h2tC:
19.48
3uftB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 3ufuA-1h2tC:
0.0
3ufuB-1h2tC:
0.0
3ufuA-1h2tC:
19.48
3ufuB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.27A 3ufuA-1h2tC:
0.0
3ufuB-1h2tC:
0.0
3ufuA-1h2tC:
19.48
3ufuB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.36A 3ufvA-1h2tC:
0.0
3ufvB-1h2tC:
0.0
3ufvA-1h2tC:
19.48
3ufvB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.44A 3ufvA-1h2tC:
0.0
3ufvB-1h2tC:
0.0
3ufvA-1h2tC:
19.48
3ufvB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
5 / 12 MET C 405
ARG C 746
LEU C 402
THR C 395
PHE C 356
None
1.46A 3vhuA-1h2tC:
undetectable
3vhuA-1h2tC:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.49A 4c39A-1h2tC:
0.0
4c39B-1h2tC:
0.0
4c39A-1h2tC:
19.48
4c39B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.30A 4camA-1h2tC:
0.0
4camB-1h2tC:
0.0
4camA-1h2tC:
19.48
4camB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 4camA-1h2tC:
0.0
4camB-1h2tC:
0.0
4camA-1h2tC:
19.48
4camB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.39A 4canA-1h2tC:
0.0
4canB-1h2tC:
0.0
4canA-1h2tC:
19.48
4canB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 4canA-1h2tC:
0.0
4canB-1h2tC:
0.0
4canA-1h2tC:
19.48
4canB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 4caoA-1h2tC:
0.0
4caoB-1h2tC:
0.0
4caoA-1h2tC:
19.48
4caoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.35A 4caoA-1h2tC:
0.0
4caoB-1h2tC:
0.0
4caoA-1h2tC:
19.48
4caoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 4capA-1h2tC:
0.0
4capB-1h2tC:
0.0
4capA-1h2tC:
19.48
4capB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.31A 4capA-1h2tC:
undetectable
4capB-1h2tC:
undetectable
4capA-1h2tC:
19.48
4capB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 4caqA-1h2tC:
0.0
4caqB-1h2tC:
0.0
4caqA-1h2tC:
19.48
4caqB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.35A 4caqA-1h2tC:
0.0
4caqB-1h2tC:
0.0
4caqA-1h2tC:
19.48
4caqB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 4ctpA-1h2tC:
0.0
4ctpB-1h2tC:
0.0
4ctpA-1h2tC:
19.48
4ctpB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.44A 4ctpA-1h2tC:
0.0
4ctpB-1h2tC:
0.0
4ctpA-1h2tC:
19.48
4ctpB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.47A 4ctqA-1h2tC:
0.0
4ctqB-1h2tC:
0.0
4ctqA-1h2tC:
19.48
4ctqB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.34A 4cttA-1h2tC:
0.0
4cttB-1h2tC:
0.0
4cttA-1h2tC:
19.48
4cttB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 4cttA-1h2tC:
0.0
4cttB-1h2tC:
0.0
4cttA-1h2tC:
19.48
4cttB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 4ctuA-1h2tC:
0.0
4ctuB-1h2tC:
0.0
4ctuA-1h2tC:
19.48
4ctuB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.32A 4ctuA-1h2tC:
0.0
4ctuB-1h2tC:
0.0
4ctuA-1h2tC:
19.48
4ctuB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 4ctvA-1h2tC:
0.0
4ctvB-1h2tC:
0.0
4ctvA-1h2tC:
19.48
4ctvB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 4ctvA-1h2tC:
0.0
4ctvB-1h2tC:
0.0
4ctvA-1h2tC:
19.48
4ctvB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.25A 4ctwA-1h2tC:
0.0
4ctwB-1h2tC:
0.0
4ctwA-1h2tC:
19.48
4ctwB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 4ctwA-1h2tC:
0.0
4ctwB-1h2tC:
0.0
4ctwA-1h2tC:
19.48
4ctwB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.25A 4ctxA-1h2tC:
0.0
4ctxB-1h2tC:
0.0
4ctxA-1h2tC:
19.48
4ctxB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.34A 4ctxA-1h2tC:
0.0
4ctxB-1h2tC:
0.0
4ctxA-1h2tC:
19.48
4ctxB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 4cx5A-1h2tC:
0.0
4cx5B-1h2tC:
0.0
4cx5A-1h2tC:
19.92
4cx5B-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 4cx5A-1h2tC:
0.0
4cx5B-1h2tC:
0.0
4cx5A-1h2tC:
19.92
4cx5B-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.49A 4cx6A-1h2tC:
0.0
4cx6B-1h2tC:
0.0
4cx6A-1h2tC:
19.92
4cx6B-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 4d1nA-1h2tC:
0.0
4d1nB-1h2tC:
0.0
4d1nA-1h2tC:
19.92
4d1nB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.27A 4d1nA-1h2tC:
0.0
4d1nB-1h2tC:
0.0
4d1nA-1h2tC:
19.92
4d1nB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.40A 4d1nC-1h2tC:
0.0
4d1nD-1h2tC:
0.0
4d1nC-1h2tC:
19.92
4d1nD-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 4d2yA-1h2tC:
0.0
4d2yB-1h2tC:
0.0
4d2yA-1h2tC:
19.48
4d2yB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 4d2yA-1h2tC:
0.0
4d2yB-1h2tC:
0.0
4d2yA-1h2tC:
19.48
4d2yB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 4d2zA-1h2tC:
0.0
4d2zB-1h2tC:
0.0
4d2zA-1h2tC:
19.48
4d2zB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 4d30A-1h2tC:
0.0
4d30B-1h2tC:
0.0
4d30A-1h2tC:
19.48
4d30B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 4d30A-1h2tC:
0.0
4d30B-1h2tC:
0.0
4d30A-1h2tC:
19.48
4d30B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.43A 4d31A-1h2tC:
0.0
4d31B-1h2tC:
0.0
4d31A-1h2tC:
19.48
4d31B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 4d32A-1h2tC:
0.0
4d32B-1h2tC:
0.0
4d32A-1h2tC:
19.48
4d32B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 4d3bA-1h2tC:
0.0
4d3bB-1h2tC:
0.0
4d3bA-1h2tC:
19.48
4d3bB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.21A 4d3bA-1h2tC:
0.0
4d3bB-1h2tC:
0.0
4d3bA-1h2tC:
19.48
4d3bB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 4d7oA-1h2tC:
0.0
4d7oB-1h2tC:
0.0
4d7oA-1h2tC:
19.48
4d7oB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 4d7oA-1h2tC:
0.0
4d7oB-1h2tC:
0.0
4d7oA-1h2tC:
19.48
4d7oB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 4euxA-1h2tC:
0.0
4euxB-1h2tC:
0.0
4euxA-1h2tC:
19.48
4euxB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.42A 4euxA-1h2tC:
0.0
4euxB-1h2tC:
0.0
4euxA-1h2tC:
19.48
4euxB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
3 / 3 PHE C 271
TYR C 121
TYR C 169
None
0.86A 4ffwA-1h2tC:
undetectable
4ffwA-1h2tC:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 GLY C 102
GLY C 101
ASN C  97
GLU C 106
None
1.08A 4fgkB-1h2tC:
undetectable
4fgkB-1h2tC:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 5 GLY C 102
GLY C 101
ASN C  97
GLU C 106
None
1.16A 4fglC-1h2tC:
undetectable
4fglC-1h2tC:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 4fvwA-1h2tC:
0.0
4fvwB-1h2tC:
0.0
4fvwA-1h2tC:
19.48
4fvwB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 4fvwA-1h2tC:
0.0
4fvwB-1h2tC:
0.0
4fvwA-1h2tC:
19.48
4fvwB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.23A 4fvxA-1h2tC:
0.0
4fvxB-1h2tC:
0.0
4fvxA-1h2tC:
19.48
4fvxB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.28A 4fvxA-1h2tC:
0.0
4fvxB-1h2tC:
0.0
4fvxA-1h2tC:
19.48
4fvxB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.41A 4fvyA-1h2tC:
0.0
4fvyB-1h2tC:
0.0
4fvyA-1h2tC:
19.48
4fvyB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.40A 4fvyA-1h2tC:
0.0
4fvyB-1h2tC:
0.0
4fvyA-1h2tC:
19.48
4fvyB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.30A 4fvzA-1h2tC:
0.0
4fvzB-1h2tC:
0.0
4fvzA-1h2tC:
19.48
4fvzB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.35A 4fvzA-1h2tC:
0.0
4fvzB-1h2tC:
0.0
4fvzA-1h2tC:
19.48
4fvzB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 4fw0A-1h2tC:
0.0
4fw0B-1h2tC:
0.0
4fw0A-1h2tC:
19.48
4fw0B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 4fw0A-1h2tC:
0.0
4fw0B-1h2tC:
0.0
4fw0A-1h2tC:
19.48
4fw0B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.26A 4gqeA-1h2tC:
0.0
4gqeB-1h2tC:
0.0
4gqeA-1h2tC:
19.48
4gqeB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.36A 4gqeA-1h2tC:
0.0
4gqeB-1h2tC:
0.0
4gqeA-1h2tC:
19.48
4gqeB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.31A 4imtA-1h2tC:
0.0
4imtB-1h2tC:
0.0
4imtA-1h2tC:
19.48
4imtB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 4imuA-1h2tC:
0.0
4imuB-1h2tC:
0.0
4imuA-1h2tC:
19.48
4imuB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 4imuA-1h2tC:
0.0
4imuB-1h2tC:
0.0
4imuA-1h2tC:
19.48
4imuB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.47A 4imwA-1h2tC:
0.0
4imwB-1h2tC:
0.0
4imwA-1h2tC:
19.48
4imwB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 4jsfA-1h2tC:
0.0
4jsfB-1h2tC:
0.0
4jsfA-1h2tC:
19.48
4jsfB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.45A 4jsfA-1h2tC:
0.0
4jsfB-1h2tC:
0.0
4jsfA-1h2tC:
19.48
4jsfB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.33A 4jsgA-1h2tC:
0.0
4jsgB-1h2tC:
0.0
4jsgA-1h2tC:
19.48
4jsgB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.43A 4jsgA-1h2tC:
0.0
4jsgB-1h2tC:
0.0
4jsgA-1h2tC:
19.48
4jsgB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.32A 4jsiA-1h2tC:
0.0
4jsiB-1h2tC:
0.0
4jsiA-1h2tC:
19.48
4jsiB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 4jsiA-1h2tC:
0.0
4jsiB-1h2tC:
0.0
4jsiA-1h2tC:
19.48
4jsiB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 4jsjA-1h2tC:
0.0
4jsjB-1h2tC:
0.0
4jsjA-1h2tC:
19.48
4jsjB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.23A 4jsjA-1h2tC:
0.0
4jsjB-1h2tC:
0.0
4jsjA-1h2tC:
19.48
4jsjB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 4k5dA-1h2tC:
0.0
4k5dB-1h2tC:
0.0
4k5dA-1h2tC:
19.48
4k5dB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 4k5dA-1h2tC:
0.0
4k5dB-1h2tC:
0.0
4k5dA-1h2tC:
19.48
4k5dB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 4k5eA-1h2tC:
0.0
4k5eB-1h2tC:
0.0
4k5eA-1h2tC:
19.48
4k5eB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.36A 4k5fA-1h2tC:
0.0
4k5fB-1h2tC:
0.0
4k5fA-1h2tC:
19.48
4k5fB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.33A 4k5gA-1h2tC:
0.0
4k5gB-1h2tC:
0.0
4k5gA-1h2tC:
19.48
4k5gB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.46A 4k5gA-1h2tC:
0.0
4k5gB-1h2tC:
0.0
4k5gA-1h2tC:
19.48
4k5gB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.36A 4kciA-1h2tC:
0.0
4kciB-1h2tC:
0.0
4kciA-1h2tC:
19.48
4kciB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.36A 4kckA-1h2tC:
0.0
4kckB-1h2tC:
0.0
4kckA-1h2tC:
19.48
4kckB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.41A 4kckA-1h2tC:
0.0
4kckB-1h2tC:
0.0
4kckA-1h2tC:
19.48
4kckB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.36A 4kclA-1h2tC:
0.0
4kclB-1h2tC:
0.0
4kclA-1h2tC:
19.48
4kclB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 4kcmA-1h2tC:
0.0
4kcmB-1h2tC:
0.0
4kcmA-1h2tC:
19.48
4kcmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 4kcmA-1h2tC:
0.0
4kcmB-1h2tC:
0.0
4kcmA-1h2tC:
19.48
4kcmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.40A 4kcnA-1h2tC:
0.0
4kcnB-1h2tC:
0.0
4kcnA-1h2tC:
19.48
4kcnB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.42A 4kcoA-1h2tC:
0.0
4kcoB-1h2tC:
0.0
4kcoA-1h2tC:
19.48
4kcoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 4kcoA-1h2tC:
0.0
4kcoB-1h2tC:
0.0
4kcoA-1h2tC:
19.48
4kcoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.39A 4uchA-1h2tC:
0.0
4uchB-1h2tC:
0.0
4uchA-1h2tC:
19.86
4uchB-1h2tC:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.45A 4uchA-1h2tC:
0.0
4uchB-1h2tC:
0.0
4uchA-1h2tC:
19.86
4uchB-1h2tC:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 LEU C 566
LEU C 554
PHE C 508
VAL C 572
None
1.05A 4udaA-1h2tC:
0.0
4udaA-1h2tC:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.46A 4ugzA-1h2tC:
0.0
4ugzB-1h2tC:
0.0
4ugzA-1h2tC:
19.48
4ugzB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.30A 4uh1A-1h2tC:
0.0
4uh1B-1h2tC:
0.0
4uh1A-1h2tC:
19.48
4uh1B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.43A 4uh2A-1h2tC:
0.0
4uh2B-1h2tC:
0.0
4uh2A-1h2tC:
19.48
4uh2B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.44A 4uh3A-1h2tC:
0.0
4uh3B-1h2tC:
0.0
4uh3A-1h2tC:
19.48
4uh3B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.32A 4uh4A-1h2tC:
0.0
4uh4B-1h2tC:
0.0
4uh4A-1h2tC:
19.48
4uh4B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.44A 4uh4A-1h2tC:
0.0
4uh4B-1h2tC:
0.0
4uh4A-1h2tC:
19.48
4uh4B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.38A 4uh5A-1h2tC:
0.0
4uh5B-1h2tC:
0.0
4uh5A-1h2tC:
19.89
4uh5B-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.47A 4uh5A-1h2tC:
0.0
4uh5B-1h2tC:
0.0
4uh5A-1h2tC:
19.89
4uh5B-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.44A 4uh6A-1h2tC:
0.0
4uh6B-1h2tC:
0.0
4uh6A-1h2tC:
19.89
4uh6B-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.25A 4upmA-1h2tC:
0.0
4upmB-1h2tC:
0.0
4upmA-1h2tC:
19.48
4upmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 4upmA-1h2tC:
0.0
4upmB-1h2tC:
0.0
4upmA-1h2tC:
19.48
4upmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.31A 4upnA-1h2tC:
0.0
4upnB-1h2tC:
0.0
4upnA-1h2tC:
19.48
4upnB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.41A 4upoA-1h2tC:
0.0
4upoB-1h2tC:
0.0
4upoA-1h2tC:
19.48
4upoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 4uppA-1h2tC:
0.0
4uppB-1h2tC:
0.0
4uppA-1h2tC:
19.48
4uppB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.25A 4uppA-1h2tC:
0.0
4uppB-1h2tC:
0.0
4uppA-1h2tC:
19.48
4uppB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 4v3uA-1h2tC:
0.0
4v3uB-1h2tC:
0.0
4v3uA-1h2tC:
19.92
4v3uB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.23A 4v3uA-1h2tC:
0.0
4v3uB-1h2tC:
0.0
4v3uA-1h2tC:
19.92
4v3uB-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.24A 4v3uC-1h2tC:
0.0
4v3uD-1h2tC:
0.0
4v3uC-1h2tC:
19.92
4v3uD-1h2tC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.35A 4v3vA-1h2tC:
0.0
4v3vB-1h2tC:
0.0
4v3vA-1h2tC:
19.48
4v3vB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 4v3xA-1h2tC:
0.0
4v3xB-1h2tC:
0.0
4v3xA-1h2tC:
19.48
4v3xB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.33A 4v3xA-1h2tC:
0.0
4v3xB-1h2tC:
0.0
4v3xA-1h2tC:
19.48
4v3xB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 4v3yA-1h2tC:
0.0
4v3yB-1h2tC:
0.0
4v3yA-1h2tC:
19.48
4v3yB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.26A 4v3yA-1h2tC:
0.0
4v3yB-1h2tC:
undetectable
4v3yA-1h2tC:
19.48
4v3yB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.44A 5adaA-1h2tC:
0.0
5adaB-1h2tC:
0.0
5adaA-1h2tC:
19.48
5adaB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.41A 5adcA-1h2tC:
0.0
5adcB-1h2tC:
0.0
5adcA-1h2tC:
19.48
5adcB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.37A 5adfA-1h2tC:
0.0
5adfB-1h2tC:
0.0
5adfA-1h2tC:
19.89
5adfB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.44A 5adgA-1h2tC:
0.0
5adgB-1h2tC:
0.0
5adgA-1h2tC:
19.89
5adgB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.46A 5adiA-1h2tC:
0.0
5adiB-1h2tC:
0.0
5adiA-1h2tC:
19.89
5adiB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 5agkA-1h2tC:
0.0
5agkB-1h2tC:
0.0
5agkA-1h2tC:
19.48
5agkB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 5agkA-1h2tC:
0.0
5agkB-1h2tC:
0.0
5agkA-1h2tC:
19.48
5agkB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 5aglA-1h2tC:
0.0
5aglB-1h2tC:
0.0
5aglA-1h2tC:
19.48
5aglB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.35A 5aglA-1h2tC:
0.0
5aglB-1h2tC:
0.0
5aglA-1h2tC:
19.48
5aglB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.28A 5agmA-1h2tC:
0.0
5agmB-1h2tC:
0.0
5agmA-1h2tC:
19.48
5agmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.37A 5agmA-1h2tC:
0.0
5agmB-1h2tC:
0.0
5agmA-1h2tC:
19.48
5agmB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.38A 5agnA-1h2tC:
0.0
5agnB-1h2tC:
0.0
5agnA-1h2tC:
19.48
5agnB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 5agoA-1h2tC:
0.0
5agoB-1h2tC:
0.0
5agoA-1h2tC:
19.48
5agoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 5agpA-1h2tC:
0.0
5agpB-1h2tC:
0.0
5agpA-1h2tC:
19.48
5agpB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
1.18A 5b1bC-1h2tC:
4.3
5b1bJ-1h2tC:
0.0
5b1bC-1h2tC:
14.50
5b1bJ-1h2tC:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
1.00A 5b3sC-1h2tC:
4.3
5b3sJ-1h2tC:
0.0
5b3sC-1h2tC:
14.50
5b3sJ-1h2tC:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
1.00A 5b3sP-1h2tC:
4.2
5b3sP-1h2tC:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 5 THR C 295
GLU C 353
HIS C 350
ASP C 293
None
1.20A 5c0oH-1h2tC:
undetectable
5c0oH-1h2tC:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.47A 5fvqA-1h2tC:
0.0
5fvqB-1h2tC:
0.0
5fvqA-1h2tC:
19.48
5fvqB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.46A 5fvsA-1h2tC:
0.0
5fvsB-1h2tC:
0.0
5fvsA-1h2tC:
19.48
5fvsB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.46A 5fvsA-1h2tC:
0.0
5fvsB-1h2tC:
0.0
5fvsA-1h2tC:
19.48
5fvsB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.46A 5fvtA-1h2tC:
0.0
5fvtB-1h2tC:
0.0
5fvtA-1h2tC:
19.48
5fvtB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.49A 5fvvA-1h2tC:
0.0
5fvvB-1h2tC:
0.0
5fvvA-1h2tC:
19.89
5fvvB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.49A 5fvvA-1h2tC:
0.0
5fvvB-1h2tC:
0.0
5fvvA-1h2tC:
19.89
5fvvB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.47A 5fvwA-1h2tC:
0.0
5fvwB-1h2tC:
0.0
5fvwA-1h2tC:
19.89
5fvwB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.47A 5fvwA-1h2tC:
0.0
5fvwB-1h2tC:
1.1
5fvwA-1h2tC:
19.89
5fvwB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.46A 5fvxA-1h2tC:
0.0
5fvxB-1h2tC:
0.0
5fvxA-1h2tC:
19.89
5fvxB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.30A 5fw0A-1h2tC:
0.0
5fw0B-1h2tC:
0.0
5fw0A-1h2tC:
19.48
5fw0B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.46A 5g0nA-1h2tC:
0.0
5g0nB-1h2tC:
0.0
5g0nA-1h2tC:
19.59
5g0nB-1h2tC:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.45A 5g0nA-1h2tC:
0.0
5g0nB-1h2tC:
0.0
5g0nA-1h2tC:
19.59
5g0nB-1h2tC:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.29A 5g0oA-1h2tC:
0.0
5g0oB-1h2tC:
0.0
5g0oA-1h2tC:
19.59
5g0oB-1h2tC:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 HIS C 724
LEU C 725
CYH C 743
HIS C 777
None
1.48A 5hrqD-1h2tC:
undetectable
5hrqG-1h2tC:
undetectable
5hrqH-1h2tC:
undetectable
5hrqD-1h2tC:
4.41
5hrqG-1h2tC:
2.59
5hrqH-1h2tC:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
0.96A 5iy5C-1h2tC:
4.3
5iy5J-1h2tC:
0.0
5iy5C-1h2tC:
14.50
5iy5J-1h2tC:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
5 / 12 LEU C 398
ALA C 394
TYR C 372
MET C 371
LEU C 336
None
1.38A 5ljbA-1h2tC:
undetectable
5ljbA-1h2tC:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.44A 5unrA-1h2tC:
0.0
5unrB-1h2tC:
0.0
5unrA-1h2tC:
19.48
5unrB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.43A 5untA-1h2tC:
0.0
5untB-1h2tC:
0.0
5untA-1h2tC:
19.48
5untB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.46A 5unwA-1h2tC:
0.0
5unwB-1h2tC:
0.0
5unwA-1h2tC:
19.48
5unwB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.47A 5unzA-1h2tC:
0.0
5unzB-1h2tC:
0.0
5unzA-1h2tC:
19.48
5unzB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.47A 5uo0A-1h2tC:
0.0
5uo0B-1h2tC:
0.0
5uo0A-1h2tC:
19.48
5uo0B-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.44A 5uo1A-1h2tC:
0.0
5uo1B-1h2tC:
0.0
5uo1A-1h2tC:
19.89
5uo1B-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.38A 5uo4A-1h2tC:
0.0
5uo4B-1h2tC:
0.0
5uo4A-1h2tC:
19.89
5uo4B-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.45A 5uo5A-1h2tC:
0.0
5uo5B-1h2tC:
0.0
5uo5A-1h2tC:
19.89
5uo5B-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 4 VAL C 139
LEU C  93
ASN C 136
ASP C 133
None
1.34A 5vcyA-1h2tC:
undetectable
5vcyA-1h2tC:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.36A 5vukA-1h2tC:
0.0
5vukB-1h2tC:
0.0
5vukA-1h2tC:
19.48
5vukB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.42A 5vukA-1h2tC:
0.0
5vukB-1h2tC:
0.0
5vukA-1h2tC:
19.48
5vukB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.23A 5vulA-1h2tC:
0.0
5vulB-1h2tC:
0.0
5vulA-1h2tC:
19.48
5vulB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.23A 5vulA-1h2tC:
0.0
5vulB-1h2tC:
0.0
5vulA-1h2tC:
19.48
5vulB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.25A 5vumA-1h2tC:
0.0
5vumB-1h2tC:
0.0
5vumA-1h2tC:
19.48
5vumB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.42A 5vumA-1h2tC:
0.0
5vumB-1h2tC:
0.0
5vumA-1h2tC:
19.48
5vumB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.25A 5vunA-1h2tC:
0.0
5vunB-1h2tC:
0.0
5vunA-1h2tC:
19.48
5vunB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.42A 5vunA-1h2tC:
0.0
5vunB-1h2tC:
0.0
5vunA-1h2tC:
19.48
5vunB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.43A 5vuoA-1h2tC:
0.0
5vuoB-1h2tC:
0.0
5vuoA-1h2tC:
19.48
5vuoB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.24A 5vupA-1h2tC:
0.0
5vupB-1h2tC:
0.0
5vupA-1h2tC:
19.48
5vupB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.22A 5vupA-1h2tC:
0.0
5vupB-1h2tC:
0.0
5vupA-1h2tC:
19.48
5vupB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.38A 5vuqA-1h2tC:
0.0
5vuqB-1h2tC:
0.0
5vuqA-1h2tC:
19.48
5vuqB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.39A 5vuqA-1h2tC:
0.0
5vuqB-1h2tC:
0.0
5vuqA-1h2tC:
19.48
5vuqB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.41A 5vurA-1h2tC:
0.0
5vurB-1h2tC:
0.0
5vurA-1h2tC:
19.48
5vurB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.41A 5vusA-1h2tC:
0.0
5vusB-1h2tC:
0.0
5vusA-1h2tC:
19.48
5vusB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 5vutA-1h2tC:
0.0
5vutB-1h2tC:
0.0
5vutA-1h2tC:
19.48
5vutB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.40A 5vutA-1h2tC:
0.0
5vutB-1h2tC:
0.0
5vutA-1h2tC:
19.48
5vutB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.40A 5vuuA-1h2tC:
0.0
5vuuB-1h2tC:
0.0
5vuuA-1h2tC:
19.48
5vuuB-1h2tC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.37A 5vuvA-1h2tC:
0.0
5vuvB-1h2tC:
0.0
5vuvA-1h2tC:
19.89
5vuvB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.35A 5vuwA-1h2tC:
0.0
5vuwB-1h2tC:
0.0
5vuwA-1h2tC:
19.89
5vuwB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.44A 5vuwA-1h2tC:
0.0
5vuwB-1h2tC:
0.0
5vuwA-1h2tC:
19.89
5vuwB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.33A 5vuxA-1h2tC:
0.0
5vuxB-1h2tC:
0.0
5vuxA-1h2tC:
19.89
5vuxB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.36A 5vuyA-1h2tC:
0.0
5vuyB-1h2tC:
0.0
5vuyA-1h2tC:
19.89
5vuyB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.39A 5vuzA-1h2tC:
0.0
5vuzB-1h2tC:
0.0
5vuzA-1h2tC:
19.89
5vuzB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.44A 5vuzA-1h2tC:
0.0
5vuzB-1h2tC:
0.0
5vuzA-1h2tC:
19.89
5vuzB-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.33A 5vv2A-1h2tC:
0.0
5vv2B-1h2tC:
0.0
5vv2A-1h2tC:
19.89
5vv2B-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.45A 5vv2A-1h2tC:
0.0
5vv2B-1h2tC:
0.0
5vv2A-1h2tC:
19.89
5vv2B-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.37A 5vv3A-1h2tC:
0.0
5vv3B-1h2tC:
0.0
5vv3A-1h2tC:
19.89
5vv3B-1h2tC:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
0.94A 5z84P-1h2tC:
4.3
5z84W-1h2tC:
0.0
5z84P-1h2tC:
14.50
5z84W-1h2tC:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
0.97A 5z85P-1h2tC:
4.3
5z85W-1h2tC:
0.0
5z85P-1h2tC:
14.50
5z85W-1h2tC:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
1.00A 5z86C-1h2tC:
4.3
5z86J-1h2tC:
0.0
5z86C-1h2tC:
14.50
5z86J-1h2tC:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
0.99A 5z86P-1h2tC:
4.3
5z86W-1h2tC:
0.0
5z86P-1h2tC:
14.50
5z86W-1h2tC:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
0.97A 5zcoP-1h2tC:
4.2
5zcoW-1h2tC:
0.0
5zcoP-1h2tC:
14.50
5zcoW-1h2tC:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
0.99A 5zcpC-1h2tC:
4.3
5zcpJ-1h2tC:
0.0
5zcpC-1h2tC:
14.50
5zcpJ-1h2tC:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 6 GLN C 783
PHE C 782
PHE C 751
LEU C 747
None
0.96A 5zcpP-1h2tC:
4.3
5zcpW-1h2tC:
0.0
5zcpP-1h2tC:
14.50
5zcpW-1h2tC:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.48A 6aurA-1h2tC:
0.0
6aurB-1h2tC:
0.0
6aurA-1h2tC:
8.20
6aurB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.27A 6ausA-1h2tC:
0.0
6ausB-1h2tC:
0.0
6ausA-1h2tC:
8.20
6ausB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.45A 6ausA-1h2tC:
0.0
6ausB-1h2tC:
0.0
6ausA-1h2tC:
8.20
6ausB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.47A 6autA-1h2tC:
0.0
6autB-1h2tC:
0.0
6autA-1h2tC:
8.20
6autB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.47A 6autA-1h2tC:
0.0
6autB-1h2tC:
0.0
6autA-1h2tC:
8.20
6autB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.45A 6auvA-1h2tC:
0.0
6auvB-1h2tC:
0.0
6auvA-1h2tC:
8.20
6auvB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.48A 6auvA-1h2tC:
0.0
6auvB-1h2tC:
0.0
6auvA-1h2tC:
8.20
6auvB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.44A 6auwA-1h2tC:
0.0
6auwB-1h2tC:
0.0
6auwA-1h2tC:
8.20
6auwB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.46A 6auwA-1h2tC:
0.0
6auwB-1h2tC:
0.0
6auwA-1h2tC:
8.20
6auwB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.41A 6auxA-1h2tC:
0.0
6auxB-1h2tC:
0.0
6auxA-1h2tC:
8.20
6auxB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.40A 6auxA-1h2tC:
0.0
6auxB-1h2tC:
0.0
6auxA-1h2tC:
8.20
6auxB-1h2tC:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.36A 6auyA-1h2tC:
0.0
6auyB-1h2tC:
0.0
6auyA-1h2tC:
6.65
6auyB-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.44A 6auzA-1h2tC:
0.0
6auzB-1h2tC:
0.0
6auzA-1h2tC:
6.65
6auzB-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.45A 6av0A-1h2tC:
0.0
6av0B-1h2tC:
0.0
6av0A-1h2tC:
6.65
6av0B-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.38A 6av2A-1h2tC:
0.0
6av2B-1h2tC:
0.0
6av2A-1h2tC:
6.65
6av2B-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.42A 6av3A-1h2tC:
0.0
6av3B-1h2tC:
0.0
6av3A-1h2tC:
6.65
6av3B-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.34A 6av4A-1h2tC:
0.0
6av4B-1h2tC:
0.0
6av4A-1h2tC:
6.65
6av4B-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.48A 6av5A-1h2tC:
0.0
6av5B-1h2tC:
0.0
6av5A-1h2tC:
6.65
6av5B-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 8 PRO C 273
ILE C 195
THR C 199
TYR C 202
None
0.78A 6cduG-1h2tC:
3.4
6cduH-1h2tC:
undetectable
6cduG-1h2tC:
17.59
6cduH-1h2tC:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.44A 6cicA-1h2tC:
0.0
6cicB-1h2tC:
0.0
6cicA-1h2tC:
6.65
6cicB-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.42A 6cicA-1h2tC:
0.0
6cicB-1h2tC:
0.0
6cicA-1h2tC:
6.65
6cicB-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 MET C 291
VAL C 216
PHE C 360
GLU C 353
None
1.42A 6cidA-1h2tC:
0.0
6cidB-1h2tC:
0.0
6cidA-1h2tC:
6.65
6cidB-1h2tC:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1h2t 80 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo
sapiens)
4 / 7 PHE C 360
GLU C 353
MET C 291
VAL C 216
None
1.48A 6cidA-1h2tC:
0.0
6cidB-1h2tC:
0.0
6cidA-1h2tC:
6.65
6cidB-1h2tC:
6.65