SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		7 / 12 HIS A 181
TYR A 183
ASP A 311
HIS A 417
ASP A 418
ASP A 466
ARG A 470
 None
 1.01A 1dedA-1h3gA:
33.9		 1dedA-1h3gA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		6 / 12 HIS A 181
TYR A 183
GLU A 340
ASP A 418
ASP A 466
ARG A 470
 None
 1.30A 1dedA-1h3gA:
33.9		 1dedA-1h3gA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		8 / 12 HIS A 181
TYR A 183
ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
ARG A 470
 None
 0.78A 1dedB-1h3gA:
36.1		 1dedB-1h3gA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 TYR A 156
GLY A 159
PHE A 449
LEU A 504
ALA A 497
 None
 1.43A 1e3vA-1h3gA:
undetectable		 1e3vA-1h3gA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 7 ILE A 297
ARG A 327
TYR A 324
PHE A 320
 None
 1.16A 1e71M-1h3gA:
6.7		 1e71M-1h3gA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 7 ILE A 297
ARG A 327
TYR A 324
PHE A 320
 None
 1.14A 1e72M-1h3gA:
5.3		 1e72M-1h3gA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 10 GLY A 161
MET A 213
ILE A 157
TYR A 156
GLY A 159
 None
 1.42A 1fohA-1h3gA:
undetectable		 1fohA-1h3gA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 GLU A 454
ARG A 502
LEU A 160
TYR A 156
GLY A 487
 None
 1.26A 1httB-1h3gA:
undetectable		 1httB-1h3gA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 GLU A 454
ARG A 502
LEU A 160
TYR A 156
GLY A 487
 None
 1.27A 1httC-1h3gA:
undetectable		 1httC-1h3gA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 11 GLU A 341
GLY A 314
LEU A 328
LEU A 366
PRO A 367
 None
 1.22A 1mjqA-1h3gA:
undetectable
1mjqB-1h3gA:
undetectable		 1mjqA-1h3gA:
10.50
1mjqB-1h3gA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		8 / 12 TYR A 183
HIS A 223
ARG A 309
ASP A 311
GLU A 340
TRP A 342
HIS A 417
ASP A 418
 None
 0.48A 1mxdA-1h3gA:
25.0		 1mxdA-1h3gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		3 / 3 LEU A 391
VAL A 394
LEU A 398
 None
 0.53A 1mz9B-1h3gA:
undetectable		 1mz9B-1h3gA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_D_MTXD354_1
(PTERIDINE REDUCTASE
1)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 SER A 306
PHE A 103
PRO A 105
LEU A 366
PRO A 367
 None
 1.38A 1p33D-1h3gA:
1.2		 1p33D-1h3gA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 11 GLY A 104
GLY A 106
ILE A 109
PRO A 167
LEU A 204
 None
 1.21A 1p91A-1h3gA:
undetectable		 1p91A-1h3gA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 GLY A  22
HIS A  20
ARG A 327
ILE A 300
LEU A 305
 None
 1.19A 1r30B-1h3gA:
6.2		 1r30B-1h3gA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 7 TYR A 315
THR A 325
THR A 322
VAL A 256
 None
 1.14A 1tv8B-1h3gA:
4.0		 1tv8B-1h3gA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 7 ALA A 118
GLY A 120
GLY A 149
PHE A 485
 None
 0.65A 2c49B-1h3gA:
undetectable		 2c49B-1h3gA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		6 / 12 ILE A  75
ALA A  38
PHE A  73
ILE A  64
LEU A  90
PRO A  70
 None
 1.46A 2d0kA-1h3gA:
undetectable		 2d0kA-1h3gA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 4 LEU A 412
PRO A 447
LEU A 440
ARG A 379
 None
 1.42A 2hrcB-1h3gA:
undetectable		 2hrcB-1h3gA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 8 MET A 378
LEU A 382
ARG A 434
VAL A 542
 None
 0.95A 2po5B-1h3gA:
undetectable		 2po5B-1h3gA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		3 / 3 VAL A 288
ASN A 241
TRP A 273
 None
 1.13A 2y00B-1h3gA:
undetectable		 2y00B-1h3gA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_2
(DEOXYCYTIDINE KINASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 4 ARG A 148
ASP A 146
LEU A 170
ARG A 211
 None
CA  A 700 (-3.2A)
None
None
 1.16A 2ziaB-1h3gA:
0.0		 2ziaB-1h3gA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
 None
 0.74A 3aicA-1h3gA:
6.0		 3aicA-1h3gA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
 None
 0.72A 3aicB-1h3gA:
4.5		 3aicB-1h3gA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		6 / 12 ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
TYR A 183
 None
 0.72A 3aicC-1h3gA:
7.4		 3aicC-1h3gA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
 None
 0.82A 3aicD-1h3gA:
3.3		 3aicD-1h3gA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
 None
 0.77A 3aicE-1h3gA:
3.4		 3aicE-1h3gA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
 None
 0.76A 3aicF-1h3gA:
4.6		 3aicF-1h3gA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
 None
 0.75A 3aicG-1h3gA:
7.5		 3aicG-1h3gA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
 None
 0.79A 3aicH-1h3gA:
4.5		 3aicH-1h3gA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ASN A 409
ILE A 446
PHE A 103
GLY A 307
LEU A 366
 None
 1.02A 3hs6B-1h3gA:
0.0		 3hs6B-1h3gA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 9 LEU A 281
PHE A 269
GLY A 318
THR A 325
ILE A 310
 None
 1.19A 3jusB-1h3gA:
0.0		 3jusB-1h3gA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		3 / 3 ARG A 253
ASP A 418
GLN A 448
 None
 0.95A 3lcvB-1h3gA:
undetectable		 3lcvB-1h3gA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEK_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 116
GLY A 145
ASN A 119
ASN A 126
HIS A 138
 None
CA  A 700 ( 4.9A)
CA  A 700 (-2.9A)
None
None
 1.47A 3mekA-1h3gA:
undetectable		 3mekA-1h3gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		3 / 3 LEU A 398
ARG A 508
ASN A 436
 None
 0.72A 3qxvD-1h3gA:
3.5		 3qxvD-1h3gA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 9 ASP A 115
GLY A 144
ASP A 146
ILE A 112
GLY A 476
 None
CA  A 700 (-3.9A)
CA  A 700 (-3.2A)
None
None
 1.01A 3s53A-1h3gA:
undetectable		 3s53A-1h3gA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ILE A 112
GLY A 144
ASN A 119
LEU A 170
GLY A 476
 None
CA  A 700 (-3.9A)
CA  A 700 (-2.9A)
None
None
 1.05A 3uq6A-1h3gA:
undetectable		 3uq6A-1h3gA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ILE A 112
GLY A 144
ASN A 119
LEU A 170
GLY A 476
 None
CA  A 700 (-3.9A)
CA  A 700 (-2.9A)
None
None
 1.04A 3vaqA-1h3gA:
undetectable		 3vaqA-1h3gA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ILE A 112
GLY A 144
ASN A 119
LEU A 170
GLY A 476
 None
CA  A 700 (-3.9A)
CA  A 700 (-2.9A)
None
None
 1.05A 3vasA-1h3gA:
undetectable		 3vasA-1h3gA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ILE A 112
GLY A 144
ASN A 119
LEU A 170
GLY A 476
 None
CA  A 700 (-3.9A)
CA  A 700 (-2.9A)
None
None
 1.10A 3vasB-1h3gA:
undetectable		 3vasB-1h3gA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 11 GLY A 145
GLY A 149
ILE A 112
ASP A 146
ASN A 126
 CA  A 700 ( 4.9A)
None
None
CA  A 700 (-3.2A)
None
 1.08A 4dcmA-1h3gA:
undetectable		 4dcmA-1h3gA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 7 ASP A 152
ASP A 146
ASN A 124
ASP A 200
 None
CA  A 700 (-3.2A)
CA  A 700 (-3.0A)
None
 1.23A 4fevB-1h3gA:
1.8		 4fevB-1h3gA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 7 TRP A 477
GLY A 141
GLY A 140
GLU A 132
 None
 1.00A 4fgkB-1h3gA:
undetectable		 4fgkB-1h3gA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 6 ASP A 152
ASP A 146
ASN A 124
ASP A 200
 None
CA  A 700 (-3.2A)
CA  A 700 (-3.0A)
None
 1.22A 4gkhJ-1h3gA:
undetectable		 4gkhJ-1h3gA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 8 ASN A 409
ARG A 445
ASN A 336
ILE A 216
 None
 1.06A 4k0bA-1h3gA:
0.0		 4k0bA-1h3gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_C_RFPC1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ASP A 152
HIS A 153
SER A 451
PRO A 114
ILE A 112
 None
 1.46A 4kmuC-1h3gA:
undetectable		 4kmuC-1h3gA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		3 / 3 TYR A 313
GLN A 257
TRP A 342
 None
 1.10A 4kn2C-1h3gA:
0.0		 4kn2C-1h3gA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 8 ASN A 409
ARG A 445
ASN A 336
ILE A 216
 None
 1.03A 4l7iA-1h3gA:
0.0		 4l7iA-1h3gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 5 GLY A  17
ALA A  16
GLY A  65
PRO A  66
 None
 0.85A 4u9uA-1h3gA:
undetectable		 4u9uA-1h3gA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 5 GLY A  17
ALA A  16
GLY A  65
PRO A  66
 None
 0.82A 4u9uB-1h3gA:
undetectable		 4u9uB-1h3gA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 8 ALA A 484
PRO A 474
GLY A 487
ALA A 488
GLY A 489
 None
 1.24A 4zjzB-1h3gA:
undetectable		 4zjzB-1h3gA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 309
ASP A 311
GLU A 340
HIS A 417
ASP A 418
 None
 0.52A 5csyB-1h3gA:
18.4		 5csyB-1h3gA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 4 ALA A 175
PRO A 169
LEU A 221
HIS A 223
 None
 1.26A 5eskA-1h3gA:
0.0		 5eskA-1h3gA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		4 / 6 TYR A 450
ARG A 116
TYR A 180
TYR A 183
 None
 1.31A 5igyA-1h3gA:
2.3		 5igyA-1h3gA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ILE A 540
VAL A 591
PRO A 566
LEU A 562
GLU A 594
 None
 1.34A 5mqtC-1h3gA:
undetectable		 5mqtC-1h3gA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXD_A_SAMA501_0
(SMYD3
METHYLTRANSFERASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 116
GLY A 145
ASN A 119
ASN A 126
HIS A 138
 None
CA  A 700 ( 4.9A)
CA  A 700 (-2.9A)
None
None
 1.48A 5xxdA-1h3gA:
undetectable		 5xxdA-1h3gA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXG_A_SAMA502_0
(SMYD3)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 116
GLY A 144
ASN A 119
ASN A 126
HIS A 138
 None
CA  A 700 (-3.9A)
CA  A 700 (-2.9A)
None
None
 1.47A 5xxgA-1h3gA:
undetectable		 5xxgA-1h3gA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXJ_A_SAMA505_0
(SMYD3)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 ARG A 116
GLY A 144
ASN A 119
ASN A 126
HIS A 138
 None
CA  A 700 (-3.9A)
CA  A 700 (-2.9A)
None
None
 1.47A 5xxjA-1h3gA:
undetectable		 5xxjA-1h3gA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 12 TYR A 183
HIS A 223
ASP A 311
HIS A 417
ASP A 418
 None
 0.39A 6ag0A-1h3gA:
21.9		 6ag0A-1h3gA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		3 / 3 LEU A 410
ASP A 107
ILE A 216
 None
 0.59A 6dh0B-1h3gA:
0.0		 6dh0B-1h3gA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		5 / 11 TYR A 404
ASP A 401
MET A 443
LEU A 412
GLY A 339
 None
 1.19A 6euqA-1h3gA:
0.0		 6euqA-1h3gA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		3 / 3 ASN A 336
PRO A 367
GLN A 353
 None
 0.94A 6jnhA-1h3gA:
0.0		 6jnhA-1h3gA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1h3g CYCLOMALTODEXTRINASE
(Flavobacterium
sp.
92) 		3 / 3 ASN A 336
PRO A 367
GLN A 353
 None
 0.94A 6jogA-1h3gA:
0.0		 6jogA-1h3gA:
15.12