SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.85A 1a7yB-1h3pH:
undetectable		 1a7yB-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.74A 1a7yB-1h3pH:
undetectable		 1a7yB-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.85A 1i3wE-1h3pH:
undetectable		 1i3wE-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.85A 1i3wE-1h3pH:
undetectable		 1i3wE-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.80A 1i3wG-1h3pH:
undetectable		 1i3wG-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.85A 1i3wG-1h3pH:
undetectable		 1i3wG-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.84A 1i3wH-1h3pH:
undetectable		 1i3wH-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.77A 1qfiB-1h3pH:
undetectable		 1qfiB-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.76A 1unjF-1h3pH:
undetectable		 1unjF-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.81A 1unjF-1h3pH:
undetectable		 1unjF-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.80A 1unjL-1h3pH:
undetectable		 1unjL-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.86A 1unjL-1h3pH:
undetectable		 1unjL-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.86A 1unjR-1h3pH:
undetectable		 1unjR-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.83A 1unjR-1h3pH:
undetectable		 1unjR-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.86A 1unjW-1h3pH:
undetectable		 1unjW-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.82A 1unjX-1h3pH:
undetectable		 1unjX-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.83A 1unjX-1h3pH:
undetectable		 1unjX-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.82A 1unmE-1h3pH:
undetectable		 1unmE-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.84A 1unmE-1h3pH:
undetectable		 1unmE-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.84A 1unmF-1h3pH:
undetectable		 1unmF-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.83A 1unmF-1h3pH:
undetectable		 1unmF-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.80A 209dC-1h3pH:
undetectable		 209dC-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  62
THR H  64
PRO H  60
 None
 0.74A 209dC-1h3pH:
undetectable		 209dC-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		4 / 8 THR H  68
PHE H  67
THR H  64
ASP H  86
 None
 1.27A 2kotB-1h3pH:
undetectable		 2kotB-1h3pH:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 TYR H 176
GLY H 144
PHE H 146
 None
 0.72A 2m2pB-1h3pH:
undetectable		 2m2pB-1h3pH:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		5 / 12 VAL H 164
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.45A 2y03A-1h3pH:
undetectable		 2y03A-1h3pH:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		5 / 12 VAL H 164
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.47A 2y03B-1h3pH:
undetectable		 2y03B-1h3pH:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 THR H  64
PRO H  60
THR H  62
 None
 0.87A 316dC-1h3pH:
undetectable		 316dC-1h3pH:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		4 / 5 TYR H  90
LEU H  80
LEU H  82
ARG H  66
 None
 1.25A 4em2A-1h3pH:
undetectable		 4em2A-1h3pH:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		5 / 10 VAL H 164
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.44A 4ldoA-1h3pH:
undetectable		 4ldoA-1h3pH:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.84A 5ecoD-1h3pH:
0.0		 5ecoD-1h3pH:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		3 / 3 SER H 204
ALA H 199
VAL H 198
 None
 0.52A 5xiwC-1h3pH:
undetectable		 5xiwC-1h3pH:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1h3p ANTIBODY FAB
FRAGMENT
(Mus
musculus) 		5 / 12 VAL H 164
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.44A 6h7mB-1h3pH:
undetectable		 6h7mB-1h3pH:
19.43