SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h59'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 1h59 INSULIN-LIKE GROWTH
FACTOR BINDING
PROTEIN 5
(Homo
sapiens) 		3 / 3 LYS B  68
PRO B  69
LEU B  70
 None
 0.88A 3tpxE-1h59B:
undetectable		 3tpxE-1h59B:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1h59 INSULIN-LIKE GROWTH
FACTOR BINDING
PROTEIN 5
(Homo
sapiens) 		3 / 3 HIS B  71
HIS B  75
ARG B  77
 None
 1.05A 6b58A-1h59B:
undetectable		 6b58A-1h59B:
7.18