SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 1h5p NUCLEAR AUTOANTIGEN
SP100-B
(Homo
sapiens) 		4 / 5 VAL A 607
VAL A 612
GLY A 610
PHE A 643
 None
 0.99A 5d4nA-1h5pA:
0.0
5d4nC-1h5pA:
0.0		 5d4nA-1h5pA:
19.09
5d4nC-1h5pA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1h5p NUCLEAR AUTOANTIGEN
SP100-B
(Homo
sapiens) 		4 / 4 LEU A 666
TYR A 617
PRO A 606
ILE A 598
 None
 1.41A 5esgA-1h5pA:
undetectable		 5esgA-1h5pA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1h5p NUCLEAR AUTOANTIGEN
SP100-B
(Homo
sapiens) 		4 / 6 GLY A 610
ASP A 648
SER A 658
ARG A 660
 None
 1.21A 6dwdA-1h5pA:
0.0
6dwdC-1h5pA:
0.0		 6dwdA-1h5pA:
12.40
6dwdC-1h5pA:
12.40