SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 7 GLY A 267
ILE A 411
TYR A 412
GLY A 261
 None
 0.82A 11gsB-1h6dA:
undetectable		 11gsB-1h6dA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 LEU A 158
PRO A 159
LEU A 162
 NDP  A 500 (-4.1A)
NDP  A 500 (-4.1A)
None
 0.47A 1hrkA-1h6dA:
undetectable		 1hrkA-1h6dA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 ILE A 411
GLY A 267
SER A 239
GLY A 260
TYR A 412
 None
 1.09A 1kiaA-1h6dA:
5.0		 1kiaA-1h6dA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 4 LEU A 158
PRO A 159
LEU A 162
ARG A 169
 NDP  A 500 (-4.1A)
NDP  A 500 (-4.1A)
None
None
 1.23A 2qd2A-1h6dA:
undetectable		 2qd2A-1h6dA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 LEU A 158
PRO A 159
LEU A 162
 NDP  A 500 (-4.1A)
NDP  A 500 (-4.1A)
None
 0.44A 2qd5B-1h6dA:
2.6		 2qd5B-1h6dA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 7 ALA A 410
VAL A 187
ASP A 404
ARG A 275
 None
 0.83A 2uyqA-1h6dA:
undetectable		 2uyqA-1h6dA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 MET A 342
ILE A 353
ASN A 272
LEU A 340
ILE A 223
 None
 1.21A 3a50A-1h6dA:
undetectable		 3a50A-1h6dA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 11 MET A 342
ILE A 353
ASN A 272
LEU A 340
ILE A 223
 None
 1.17A 3a50B-1h6dA:
0.0		 3a50B-1h6dA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 11 MET A 342
ILE A 353
ASN A 272
LEU A 340
ILE A 223
 None
 1.20A 3a50C-1h6dA:
0.0		 3a50C-1h6dA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 MET A 342
ILE A 353
ASN A 272
LEU A 340
ILE A 223
 None
 1.28A 3a50E-1h6dA:
undetectable		 3a50E-1h6dA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 11 MET A 342
ILE A 353
ASN A 272
LEU A 340
ILE A 223
 None
 1.17A 3a51A-1h6dA:
0.0		 3a51A-1h6dA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 MET A 342
ILE A 353
ASN A 272
LEU A 340
ILE A 223
 None
 1.21A 3a51D-1h6dA:
0.0		 3a51D-1h6dA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 CYH A 190
PRO A 397
ASP A 404
 None
 0.96A 3hlwB-1h6dA:
0.0		 3hlwB-1h6dA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEK_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 GLY A 347
ASN A 238
ASN A 216
HIS A 211
TYR A 276
 None
 1.34A 3mekA-1h6dA:
undetectable		 3mekA-1h6dA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 GLY A  92
ILE A 124
VAL A 125
 NDP  A 500 (-3.0A)
None
None
 0.45A 3nv6A-1h6dA:
undetectable		 3nv6A-1h6dA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 TYR A 155
GLU A 180
LYS A 175
ALA A 153
PHE A 142
 None
NDP  A 500 (-3.2A)
None
None
None
 1.17A 3qowA-1h6dA:
2.6		 3qowA-1h6dA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWP_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 GLY A 347
ASN A 238
ASN A 216
HIS A 211
TYR A 276
 None
 1.35A 3qwpA-1h6dA:
undetectable		 3qwpA-1h6dA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 8 GLY A 260
MET A 264
GLY A 267
ILE A 411
LEU A 271
 None
 1.23A 3v1nA-1h6dA:
undetectable		 3v1nA-1h6dA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 LEU A 158
PRO A 159
LEU A 162
 NDP  A 500 (-4.1A)
NDP  A 500 (-4.1A)
None
 0.40A 3w1wB-1h6dA:
2.4		 3w1wB-1h6dA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 6 TYR A 412
GLN A 409
ARG A 255
GLU A 180
 None
None
None
NDP  A 500 (-3.2A)
 1.28A 4ax8A-1h6dA:
4.0		 4ax8A-1h6dA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 6 TYR A 412
GLN A 409
ARG A 255
GLU A 180
 None
None
None
NDP  A 500 (-3.2A)
 1.30A 4azvA-1h6dA:
3.8		 4azvA-1h6dA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 5 LEU A 263
LEU A 271
MET A 309
THR A 236
 None
 1.49A 4do3A-1h6dA:
0.2		 4do3A-1h6dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 6 LEU A 114
TYR A 137
LYS A 135
GLU A 112
 None
 1.19A 4f3tA-1h6dA:
4.9		 4f3tA-1h6dA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 GLY A 259
ALA A 258
SER A 161
LEU A 162
LEU A 158
 None
None
None
None
NDP  A 500 (-4.1A)
 0.92A 4o1zA-1h6dA:
0.0		 4o1zA-1h6dA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 CYH A 190
PRO A 397
ASP A 404
 None
 0.98A 4pm5A-1h6dA:
0.0		 4pm5A-1h6dA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 11 ALA A 127
TYR A 129
LEU A  91
LEU A  96
LEU A 100
 None
None
NDP  A 500 (-3.8A)
None
None
 0.91A 4wg0C-1h6dA:
undetectable
4wg0D-1h6dA:
undetectable
4wg0E-1h6dA:
undetectable		 4wg0C-1h6dA:
3.49
4wg0D-1h6dA:
3.49
4wg0E-1h6dA:
3.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 11 ALA A 127
TYR A 129
LEU A  91
LEU A  96
LEU A 100
 None
None
NDP  A 500 (-3.8A)
None
None
 0.89A 4wg0E-1h6dA:
undetectable
4wg0F-1h6dA:
undetectable
4wg0G-1h6dA:
undetectable		 4wg0E-1h6dA:
3.49
4wg0F-1h6dA:
3.49
4wg0G-1h6dA:
3.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 6 LEU A 114
TYR A 137
LYS A 135
GLU A 112
 None
 1.27A 4z4gA-1h6dA:
4.1		 4z4gA-1h6dA:
17.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		6 / 7 LYS A 181
ARG A 209
ARG A 252
ASP A 265
TYR A 269
TYR A 348
 GOL  A 600 ( 2.5A)
NDP  A 500 (-4.0A)
NDP  A 500 ( 2.8A)
GOL  A 600 (-2.9A)
GOL  A 600 ( 4.3A)
NDP  A 500 (-4.8A)
 0.40A 5a06A-1h6dA:
48.8		 5a06A-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 7 ILE A 194
LYS A 203
LEU A 204
GLY A 398
 None
 0.18A 5a06A-1h6dA:
48.8		 5a06A-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		6 / 7 LYS A 181
ARG A 209
ARG A 252
ASP A 265
ILE A 266
TYR A 269
 GOL  A 600 ( 2.5A)
NDP  A 500 (-4.0A)
NDP  A 500 ( 2.8A)
GOL  A 600 (-2.9A)
None
GOL  A 600 ( 4.3A)
 0.54A 5a06B-1h6dA:
48.6		 5a06B-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 7 ILE A 194
LYS A 203
LEU A 204
GLY A 398
 None
 0.19A 5a06B-1h6dA:
48.6		 5a06B-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		6 / 7 LYS A 181
ARG A 209
ARG A 252
ASP A 265
TYR A 269
TYR A 348
 GOL  A 600 ( 2.5A)
NDP  A 500 (-4.0A)
NDP  A 500 ( 2.8A)
GOL  A 600 (-2.9A)
GOL  A 600 ( 4.3A)
NDP  A 500 (-4.8A)
 0.38A 5a06C-1h6dA:
48.7		 5a06C-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 7 ILE A 194
LYS A 203
LEU A 204
GLY A 398
 None
 0.16A 5a06C-1h6dA:
48.7		 5a06C-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		6 / 7 LYS A 181
ARG A 209
ARG A 252
ASP A 265
TYR A 269
TYR A 348
 GOL  A 600 ( 2.5A)
NDP  A 500 (-4.0A)
NDP  A 500 ( 2.8A)
GOL  A 600 (-2.9A)
GOL  A 600 ( 4.3A)
NDP  A 500 (-4.8A)
 0.38A 5a06D-1h6dA:
48.5		 5a06D-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 7 ILE A 194
LYS A 203
LEU A 204
GLY A 398
 None
 0.17A 5a06E-1h6dA:
48.6		 5a06E-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		6 / 7 LYS A 181
ARG A 209
ARG A 252
ASP A 265
TYR A 269
TYR A 348
 GOL  A 600 ( 2.5A)
NDP  A 500 (-4.0A)
NDP  A 500 ( 2.8A)
GOL  A 600 (-2.9A)
GOL  A 600 ( 4.3A)
NDP  A 500 (-4.8A)
 0.40A 5a06E-1h6dA:
48.6		 5a06E-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 7 ILE A 194
LYS A 203
LEU A 204
GLY A 398
 None
 0.16A 5a06F-1h6dA:
48.6		 5a06F-1h6dA:
44.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		6 / 7 LYS A 181
ARG A 209
ARG A 252
ASP A 265
TYR A 269
TYR A 348
 GOL  A 600 ( 2.5A)
NDP  A 500 (-4.0A)
NDP  A 500 ( 2.8A)
GOL  A 600 (-2.9A)
GOL  A 600 ( 4.3A)
NDP  A 500 (-4.8A)
 0.41A 5a06F-1h6dA:
48.6		 5a06F-1h6dA:
44.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCL_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 GLY A 347
ASN A 238
ASN A 216
HIS A 211
TYR A 276
 None
 1.36A 5cclA-1h6dA:
undetectable		 5cclA-1h6dA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 8 ILE A 266
ARG A 252
GLY A 261
ASN A 160
 None
NDP  A 500 ( 2.8A)
None
NDP  A 500 (-3.7A)
 0.94A 5hwaA-1h6dA:
0.0		 5hwaA-1h6dA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		4 / 8 ILE A 268
ASP A 404
ARG A 275
LEU A 277
 None
 0.97A 5hwaA-1h6dA:
0.0		 5hwaA-1h6dA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 ILE A  99
ALA A  95
TYR A  94
GLY A 105
PHE A 103
 None
None
NDP  A 500 (-3.4A)
None
None
 0.94A 5i73A-1h6dA:
0.0		 5i73A-1h6dA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 ILE A  99
ALA A  95
TYR A  94
GLY A 105
PHE A 103
 None
None
NDP  A 500 (-3.4A)
None
None
 0.92A 5i75A-1h6dA:
0.0		 5i75A-1h6dA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 THR A 185
MET A 183
HIS A 163
 None
None
NDP  A 500 (-3.9A)
 0.88A 5uunA-1h6dA:
0.5		 5uunA-1h6dA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXJ_A_SAMA505_0
(SMYD3)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		5 / 12 GLY A 347
ASN A 238
ASN A 216
HIS A 211
TYR A 276
 None
 1.34A 5xxjA-1h6dA:
undetectable		 5xxjA-1h6dA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 LEU A 316
THR A 423
ASN A 422
 None
 0.58A 6baaE-1h6dA:
0.0		 6baaE-1h6dA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 LEU A 316
THR A 423
ASN A 422
 None
 0.58A 6baaF-1h6dA:
0.0		 6baaF-1h6dA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 LEU A 316
THR A 423
ASN A 422
 None
 0.59A 6baaG-1h6dA:
0.0		 6baaG-1h6dA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE
(Zymomonas
mobilis) 		3 / 3 LEU A 316
THR A 423
ASN A 422
 None
 0.59A 6baaH-1h6dA:
0.0		 6baaH-1h6dA:
14.11