SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 1h6f T-BOX TRANSCRIPTION
FACTOR TBX3
(Homo
sapiens) 		4 / 8 SER A 246
ILE A 240
LEU A 152
VAL A 235
 None
 0.80A 3dcjB-1h6fA:
undetectable		 3dcjB-1h6fA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1h6f T-BOX TRANSCRIPTION
FACTOR TBX3
(Homo
sapiens) 		4 / 7 THR A 256
LEU A 107
VAL A 138
THR A 203
 None
 0.97A 3fwiA-1h6fA:
undetectable		 3fwiA-1h6fA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 1h6f T-BOX TRANSCRIPTION
FACTOR TBX3
(Homo
sapiens) 		3 / 3 ASP A 154
LEU A 207
VAL A 202
 None
 0.64A 4jecB-1h6fA:
undetectable		 4jecB-1h6fA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1h6f T-BOX TRANSCRIPTION
FACTOR TBX3
(Homo
sapiens) 		4 / 8 LEU A 107
LEU A 112
ILE A 259
THR A 121
 None
 1.06A 5ljbA-1h6fA:
undetectable		 5ljbA-1h6fA:
17.61