SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 9 ILE P 236
LEU P 247
VAL P 323
GLY P 322
ALA P 320
None
1.21A 1e7aA-1h71P:
undetectable
1e7aA-1h71P:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 9 ILE P 236
LEU P 247
VAL P 323
GLY P 322
ALA P 320
None
1.15A 1e7bA-1h71P:
0.8
1e7bA-1h71P:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 6 LEU P  40
ASP P 234
LEU P 232
ARG P  20
None
1.07A 1mt1A-1h71P:
0.0
1mt1F-1h71P:
0.0
1mt1A-1h71P:
10.27
1mt1F-1h71P:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.28A 1os2A-1h71P:
13.3
1os2A-1h71P:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.32A 1os2D-1h71P:
13.3
1os2D-1h71P:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 7 LEU P 276
VAL P 310
GLY P 311
ASP P 290
None
0.75A 1p2yA-1h71P:
0.0
1p2yA-1h71P:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 12 LEU P 436
VAL P 438
PHE P 448
VAL P 450
THR P 452
None
1.32A 1q23B-1h71P:
0.0
1q23B-1h71P:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 10 THR P 166
HIS P 169
GLU P 170
HIS P 173
HIS P 179
None
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.49A 1r55A-1h71P:
4.7
1r55A-1h71P:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 7 LEU P 276
VAL P 310
GLY P 311
ASP P 290
None
0.72A 1t88A-1h71P:
0.0
1t88A-1h71P:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.32A 1uttA-1h71P:
13.2
1uttA-1h71P:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.27A 1utzA-1h71P:
12.8
1utzA-1h71P:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.30A 1utzB-1h71P:
12.8
1utzB-1h71P:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 1v54A-1h71P:
undetectable
1v54A-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 1v54N-1h71P:
undetectable
1v54N-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.74A 1v55A-1h71P:
undetectable
1v55A-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 1v55N-1h71P:
undetectable
1v55N-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 6 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.33A 1y93A-1h71P:
12.7
1y93A-1h71P:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 8 LEU P 276
VAL P 310
GLY P 311
ASP P 290
None
0.77A 2a1oA-1h71P:
0.0
2a1oA-1h71P:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 6 ARG P 164
SER P  95
PHE P 266
GLU P  94
None
1.41A 2c8aC-1h71P:
undetectable
2c8aC-1h71P:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.75A 2dyrA-1h71P:
undetectable
2dyrA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 2dyrN-1h71P:
undetectable
2dyrN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.73A 2eijA-1h71P:
undetectable
2eijA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.75A 2eijN-1h71P:
undetectable
2eijN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.77A 2eikN-1h71P:
undetectable
2eikN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 2eilN-1h71P:
undetectable
2eilN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.75A 2eimA-1h71P:
0.0
2eimA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.74A 2einA-1h71P:
undetectable
2einA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 VAL P 456
VAL P 453
ASP P 353
None
None
CA  P 503 ( 2.5A)
0.78A 2fumD-1h71P:
0.0
2fumD-1h71P:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 7 TYR P 183
TYR P 162
GLU P 170
HIS P 173
None
None
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
1.14A 2ha4B-1h71P:
undetectable
2ha4B-1h71P:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.31A 2hu6A-1h71P:
12.9
2hu6A-1h71P:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 9 THR P 166
HIS P 169
GLU P 170
HIS P 173
HIS P 179
None
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.35A 2jihA-1h71P:
7.0
2jihA-1h71P:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 8 THR P 166
HIS P 169
GLU P 170
HIS P 173
HIS P 179
None
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.33A 2jihB-1h71P:
3.0
2jihB-1h71P:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 6 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.16A 2ow9A-1h71P:
13.1
2ow9A-1h71P:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.22A 2ow9B-1h71P:
13.0
2ow9B-1h71P:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.18A 2ozrC-1h71P:
13.1
2ozrC-1h71P:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.21A 2ozrD-1h71P:
13.2
2ozrD-1h71P:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.31A 2ozrE-1h71P:
13.1
2ozrE-1h71P:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 169
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.24A 2ozrF-1h71P:
13.1
2ozrF-1h71P:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 SER P 379
ASP P 362
ASP P 341
None
CA  P 505 ( 2.4A)
None
0.80A 2plwA-1h71P:
undetectable
2plwA-1h71P:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 7 LEU P  40
ASP P 234
LEU P 232
ARG P  20
None
1.04A 2qqcG-1h71P:
undetectable
2qqcJ-1h71P:
0.0
2qqcG-1h71P:
7.38
2qqcJ-1h71P:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 6 PHE P   8
ILE P  11
GLY P 358
GLY P 357
None
None
CA  P 505 (-4.3A)
CA  P 505 (-4.3A)
0.72A 2qx6A-1h71P:
2.0
2qx6B-1h71P:
2.0
2qx6A-1h71P:
17.72
2qx6B-1h71P:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.75A 2y69A-1h71P:
undetectable
2y69A-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.78A 2zxwA-1h71P:
undetectable
2zxwA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.78A 2zxwN-1h71P:
undetectable
2zxwN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.77A 3ablA-1h71P:
undetectable
3ablA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 3abmA-1h71P:
undetectable
3abmA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.75A 3bvdA-1h71P:
undetectable
3bvdA-1h71P:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.74A 3dtuA-1h71P:
undetectable
3dtuA-1h71P:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 ASN P 334
ASP P 397
GLN P 393
None
CA  P 501 (-2.6A)
CA  P 501 (-3.6A)
0.74A 3eeyC-1h71P:
undetectable
3eeyC-1h71P:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 ASN P 334
ASP P 397
GLN P 393
None
CA  P 501 (-2.6A)
CA  P 501 (-3.6A)
0.75A 3eeyD-1h71P:
undetectable
3eeyD-1h71P:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 ASN P 334
ASP P 397
GLN P 393
None
CA  P 501 (-2.6A)
CA  P 501 (-3.6A)
0.74A 3eeyE-1h71P:
undetectable
3eeyE-1h71P:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 9 GLN P 165
VAL P 206
ASP P 235
ILE P 236
VAL P  99
None
1.45A 3fi0D-1h71P:
undetectable
3fi0D-1h71P:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 9 THR P 166
HIS P 169
GLU P 170
HIS P 173
HIS P 179
None
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.31A 3hy7A-1h71P:
4.2
3hy7A-1h71P:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 9 THR P 166
HIS P 169
GLU P 170
HIS P 173
HIS P 179
None
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.31A 3hy7B-1h71P:
7.2
3hy7B-1h71P:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.22A 3kecA-1h71P:
13.1
3kecA-1h71P:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 169
GLU P 170
HIS P 173
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
0.18A 3kecB-1h71P:
13.0
3kecB-1h71P:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.30A 3likA-1h71P:
13.0
3likA-1h71P:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.31A 3lilA-1h71P:
13.1
3lilA-1h71P:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.35A 3ljgA-1h71P:
13.0
3ljgA-1h71P:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.32A 3lkaA-1h71P:
12.9
3lkaA-1h71P:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 8 SER P 137
GLN P 117
ASN P 136
TRP P  47
None
1.18A 3n62A-1h71P:
0.0
3n62A-1h71P:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 ASP P 397
SER P 370
GLY P 369
ASP P 391
CA  P 501 (-2.6A)
None
CA  P 502 (-4.4A)
None
1.02A 3w9tB-1h71P:
0.0
3w9tB-1h71P:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 ASP P 397
SER P 370
GLY P 369
ASP P 391
CA  P 501 (-2.6A)
None
CA  P 502 (-4.4A)
None
1.03A 3w9tC-1h71P:
0.0
3w9tC-1h71P:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 ASP P 397
SER P 370
GLY P 369
ASP P 391
CA  P 501 (-2.6A)
None
CA  P 502 (-4.4A)
None
1.03A 3w9tD-1h71P:
0.0
3w9tD-1h71P:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.73A 3wg7A-1h71P:
undetectable
3wg7A-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.75A 3wg7N-1h71P:
undetectable
3wg7N-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.72A 3x2qN-1h71P:
undetectable
3x2qN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 6 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.16A 4a7bA-1h71P:
13.1
4a7bA-1h71P:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 8 SER P   6
LEU P 401
ALA P 403
SER P   5
None
0.81A 4ikjA-1h71P:
undetectable
4ikjB-1h71P:
undetectable
4ikjA-1h71P:
16.93
4ikjB-1h71P:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 8 LEU P 401
ALA P 403
SER P   5
SER P   6
None
0.81A 4ikkA-1h71P:
undetectable
4ikkB-1h71P:
undetectable
4ikkA-1h71P:
16.93
4ikkB-1h71P:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 8 SER P   6
LEU P 401
ALA P 403
SER P   5
None
0.88A 4iklA-1h71P:
undetectable
4iklB-1h71P:
undetectable
4iklA-1h71P:
16.93
4iklB-1h71P:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 12 GLY P 376
ALA P 403
ASN P  13
SER P  15
ILE P 338
None
1.24A 4pb1A-1h71P:
0.0
4pb1A-1h71P:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 ASP P 341
GLY P 360
ASP P 362
None
CA  P 504 (-4.5A)
CA  P 505 ( 2.4A)
0.68A 4xdtA-1h71P:
0.0
4xdtA-1h71P:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 GLY P 376
VAL P 374
PHE P  14
ILE P 338
None
0.92A 4xv2B-1h71P:
0.0
4xv2B-1h71P:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 ASN P 301
LEU P 233
PHE P  17
None
0.81A 5dsgA-1h71P:
undetectable
5dsgA-1h71P:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 7 ARG P 250
THR P 254
ASP P 282
ASP P 252
None
CA  P 507 (-3.5A)
CA  P 507 (-2.3A)
None
1.05A 5hwaA-1h71P:
1.4
5hwaA-1h71P:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 SER P 229
LEU P 177
MET P 207
None
0.87A 5ikrB-1h71P:
0.0
5ikrB-1h71P:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 6 SER P 306
GLY P 339
ASN P 340
ILE P 300
None
CA  P 505 ( 4.7A)
None
None
0.90A 5j4nA-1h71P:
0.0
5j4nA-1h71P:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 8 SER P   5
THR P   4
THR P 402
ILE P  11
None
1.09A 5jhdE-1h71P:
0.0
5jhdG-1h71P:
0.1
5jhdE-1h71P:
21.03
5jhdG-1h71P:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 4 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.31A 5n5jA-1h71P:
12.8
5n5jA-1h71P:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 HIS P 169
GLU P 170
HIS P 173
HIS P 179
ZN  P 600 (-3.4A)
ZN  P 600 ( 4.0A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.30A 5n5kA-1h71P:
12.5
5n5kA-1h71P:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.73A 5w97a-1h71P:
undetectable
5w97a-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.70A 5x1bA-1h71P:
undetectable
5x1bA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.74A 5x1fA-1h71P:
undetectable
5x1fA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.68A 5x1fN-1h71P:
undetectable
5x1fN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.75A 5xdqA-1h71P:
undetectable
5xdqA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 5xdqN-1h71P:
undetectable
5xdqN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.74A 5xdxA-1h71P:
undetectable
5xdxA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.73A 5xdxN-1h71P:
undetectable
5xdxN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 HIS P  23
ALA P 198
SER P  30
TYR P 204
None
1.24A 5yodD-1h71P:
undetectable
5yodD-1h71P:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
4 / 5 HIS P  23
ALA P 198
SER P  30
TYR P 204
None
1.39A 5yodF-1h71P:
undetectable
5yodF-1h71P:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 5z84N-1h71P:
undetectable
5z84N-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 5z85N-1h71P:
undetectable
5z85N-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.78A 5z86N-1h71P:
undetectable
5z86N-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.77A 5zcoA-1h71P:
undetectable
5zcoA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.73A 5zcoN-1h71P:
undetectable
5zcoN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 5zcpA-1h71P:
undetectable
5zcpA-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.78A 5zcpN-1h71P:
undetectable
5zcpN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 5zcqN-1h71P:
undetectable
5zcqN-1h71P:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
5 / 7 GLY P 331
GLY P 330
GLY P 348
GLY P 366
GLY P 367
CA  P 503 (-4.4A)
CA  P 503 ( 4.8A)
CA  P 503 (-4.3A)
CA  P 501 (-4.4A)
CA  P 502 (-4.2A)
1.01A 6ag0A-1h71P:
undetectable
6ag0A-1h71P:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 LEU P 436
ASP P 362
ILE P 355
None
CA  P 505 ( 2.4A)
None
0.57A 6dh0B-1h71P:
0.0
6dh0B-1h71P:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.76A 6hu9m-1h71P:
undetectable
6hu9m-1h71P:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1h71 SERRALYSIN
(Pseudomonas
sp.
'TAC
II
18')
3 / 3 HIS P 179
HIS P 173
HIS P 169
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
ZN  P 600 (-3.4A)
0.72A 6nmfA-1h71P:
undetectable
6nmfA-1h71P:
22.06