SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		3 / 3 ALA A 528
VAL A 523
TRP A 524
 None
 0.76A 1bdwA-1h79A:
undetectable
1bdwB-1h79A:
undetectable		 1bdwA-1h79A:
2.93
1bdwB-1h79A:
2.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 VAL A  50
ILE A  68
TYR A 124
ASN A  78
ASN A 311
 None
 1.26A 1fm4A-1h79A:
undetectable		 1fm4A-1h79A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 7 ILE A 278
PHE A 293
ALA A 500
ILE A 505
 None
 0.81A 1oniB-1h79A:
1.3
1oniC-1h79A:
1.2		 1oniB-1h79A:
13.75
1oniC-1h79A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 GLY A 126
CYH A  79
LEU A 294
LEU A 370
TYR A 371
 None
 1.28A 1zgyA-1h79A:
0.0		 1zgyA-1h79A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 8 TYR A 144
TRP A 205
THR A 167
GLN A 164
 None
 0.88A 2vxaF-1h79A:
0.0
2vxaG-1h79A:
0.0
2vxaI-1h79A:
0.0		 2vxaF-1h79A:
8.83
2vxaG-1h79A:
8.83
2vxaI-1h79A:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 6 PHE A 194
TYR A 581
ARG A 291
THR A 128
 None
 1.43A 2x2iB-1h79A:
1.1		 2x2iB-1h79A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 6 ALA A 110
ALA A 113
THR A 116
PHE A 129
 TTP  A1586 ( 3.9A)
None
None
None
 1.01A 2xfhA-1h79A:
undetectable		 2xfhA-1h79A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 6 ASP A 325
ILE A 322
LEU A 317
GLU A 343
 None
 0.87A 2ya7A-1h79A:
0.0		 2ya7A-1h79A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 6 ASP A 325
ILE A 322
LEU A 317
GLU A 343
 None
 0.83A 2ya7B-1h79A:
0.0		 2ya7B-1h79A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 6 ASP A 325
ILE A 322
LEU A 317
GLU A 343
 None
 0.85A 2ya7D-1h79A:
0.0		 2ya7D-1h79A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 GLY A 502
HIS A 497
LEU A 399
SER A 398
LEU A 319
 None
 1.13A 3bxoA-1h79A:
undetectable		 3bxoA-1h79A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 GLY A 503
HIS A 497
LEU A 399
SER A 398
LEU A 319
 None
 0.87A 3bxoA-1h79A:
undetectable		 3bxoA-1h79A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 GLY A 503
HIS A 497
SER A 398
SER A 475
LEU A 319
 None
 0.99A 3bxoA-1h79A:
undetectable		 3bxoA-1h79A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 VAL A  82
THR A 116
VAL A 195
ILE A 197
THR A 127
 None
 1.08A 3czhA-1h79A:
0.0		 3czhA-1h79A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 GLY A 126
CYH A  79
LEU A 294
LEU A 370
TYR A 371
 None
 1.27A 3g9eA-1h79A:
0.0		 3g9eA-1h79A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 TYR A 507
GLY A 535
ALA A 527
ASP A 268
ILE A 269
 None
 1.16A 3id6C-1h79A:
0.9		 3id6C-1h79A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 8 SER A 398
SER A 396
GLY A 313
SER A 292
ASN A 310
 None
 0.95A 3lslA-1h79A:
undetectable
3lslD-1h79A:
undetectable		 3lslA-1h79A:
19.25
3lslD-1h79A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 8 SER A 292
ASN A 310
SER A 398
SER A 396
GLY A 313
 None
 0.97A 3lslA-1h79A:
undetectable
3lslD-1h79A:
undetectable		 3lslA-1h79A:
19.25
3lslD-1h79A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 7 GLU A 181
LEU A 185
THR A 116
ALA A 117
 None
 1.33A 3mbgA-1h79A:
0.0
3mbgB-1h79A:
0.0		 3mbgA-1h79A:
12.42
3mbgB-1h79A:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 PRO A 102
LEU A  88
LEU A  84
ALA A 108
THR A 109
 None
 1.18A 3r9cA-1h79A:
undetectable		 3r9cA-1h79A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 5 ILE A 402
PRO A 320
SER A 479
GLY A 403
 None
 1.04A 3tkdB-1h79A:
undetectable		 3tkdB-1h79A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 5 ILE A 402
PRO A 320
SER A 479
GLY A 403
 None
 1.04A 3tkdA-1h79A:
undetectable		 3tkdA-1h79A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		3 / 3 PRO A 444
THR A 443
LEU A 448
 TTP  A1589 ( 4.0A)
TTP  A1589 (-4.3A)
TTP  A1589 (-4.0A)
 0.77A 3ttrA-1h79A:
undetectable		 3ttrA-1h79A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 8 LEU A 234
ARG A 218
TYR A 178
GLU A 179
 None
 1.26A 3zmdA-1h79A:
undetectable
3zmdB-1h79A:
0.0		 3zmdA-1h79A:
14.07
3zmdB-1h79A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 8 VAL A 536
TYR A 533
VAL A 523
ILE A 269
 None
 1.16A 4aftD-1h79A:
0.0
4aftE-1h79A:
0.0		 4aftD-1h79A:
17.02
4aftE-1h79A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 11 LEU A 258
LEU A 520
PHE A 487
LEU A 244
ILE A 269
 None
 1.02A 4dm8A-1h79A:
0.0		 4dm8A-1h79A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 GLY A 126
CYH A  79
LEU A 294
LEU A 370
TYR A 371
 None
 1.27A 4emaA-1h79A:
0.0		 4emaA-1h79A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		3 / 3 LYS A 103
TYR A 139
ARG A 142
 TTP  A1586 (-4.6A)
None
None
 1.15A 4gc9A-1h79A:
undetectable		 4gc9A-1h79A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 9 TYR A 507
VAL A 235
ILE A 270
HIS A 477
LEU A 531
 None
 1.44A 4l1xB-1h79A:
2.9		 4l1xB-1h79A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		3 / 3 THR A 184
ASN A 217
PHE A 175
 None
 0.84A 4pd9A-1h79A:
0.2		 4pd9A-1h79A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		3 / 3 VAL A 285
ALA A 130
PHE A 237
 None
 0.90A 4w5nA-1h79A:
3.1		 4w5nA-1h79A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 5 PRO A 287
VAL A 285
ALA A 130
PHE A 237
 None
 0.96A 4w5oA-1h79A:
2.4		 4w5oA-1h79A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 GLY A 126
CYH A  79
LEU A 294
LEU A 370
TYR A 371
 None
 1.28A 4xldA-1h79A:
0.0		 4xldA-1h79A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 7 TYR A 507
VAL A 235
ILE A 270
HIS A 477
LEU A 531
 None
 1.41A 4xo7A-1h79A:
2.7		 4xo7A-1h79A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 4 GLY A 106
VAL A 171
PHE A 199
ILE A 214
 None
 1.07A 4xv2B-1h79A:
0.1		 4xv2B-1h79A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 5 PRO A 287
VAL A 285
ALA A 130
PHE A 237
 None
 0.99A 4z4cA-1h79A:
2.0		 4z4cA-1h79A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 5 PRO A 287
VAL A 285
ALA A 130
PHE A 237
 None
 0.97A 4z4dA-1h79A:
2.4		 4z4dA-1h79A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 5 PRO A 287
VAL A 285
ALA A 130
PHE A 237
 None
 0.96A 4z4eA-1h79A:
3.4		 4z4eA-1h79A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 5 VAL A 135
TYR A 266
ILE A 575
THR A 192
 None
 1.22A 4ze1A-1h79A:
0.0		 4ze1A-1h79A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		3 / 3 PHE A  92
ILE A 115
ASP A 307
 None
 0.76A 5cswA-1h79A:
undetectable		 5cswA-1h79A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 GLY A 403
PRO A 320
LEU A 407
ASN A 474
LEU A 420
 None
 1.39A 5emlA-1h79A:
2.6		 5emlA-1h79A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		3 / 3 PRO A 229
ARG A 264
GLU A 179
 None
 0.99A 5j6hA-1h79A:
0.0		 5j6hA-1h79A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		3 / 3 ASP A 170
ASN A 217
GLN A 176
 None
 0.68A 5k7uA-1h79A:
0.3		 5k7uA-1h79A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 ILE A 402
GLY A 403
HIS A 405
VAL A 466
ALA A 445
 None
None
None
None
TTP  A1589 (-4.8A)
 1.02A 5n0oA-1h79A:
1.6		 5n0oA-1h79A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 ILE A 402
GLY A 403
HIS A 405
VAL A 466
ALA A 445
 None
None
None
None
TTP  A1589 (-4.8A)
 1.02A 5n0oB-1h79A:
2.3		 5n0oB-1h79A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 ILE A 402
GLY A 403
HIS A 405
VAL A 466
ALA A 445
 None
None
None
None
TTP  A1589 (-4.8A)
 0.99A 5n0sA-1h79A:
2.3		 5n0sA-1h79A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 ILE A 402
GLY A 403
HIS A 405
VAL A 466
ALA A 445
 None
None
None
None
TTP  A1589 (-4.8A)
 1.08A 5n0tA-1h79A:
0.8		 5n0tA-1h79A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 ILE A 402
GLY A 403
HIS A 405
VAL A 466
ALA A 445
 None
None
None
None
TTP  A1589 (-4.8A)
 1.04A 5n0wA-1h79A:
2.1		 5n0wA-1h79A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 ILE A 402
GLY A 403
HIS A 405
VAL A 466
ALA A 445
 None
None
None
None
TTP  A1589 (-4.8A)
 1.03A 5n0wB-1h79A:
undetectable		 5n0wB-1h79A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 ILE A 402
GLY A 403
HIS A 405
VAL A 466
ALA A 445
 None
None
None
None
TTP  A1589 (-4.8A)
 1.04A 5n0xA-1h79A:
undetectable		 5n0xA-1h79A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 ILE A 402
GLY A 403
HIS A 405
VAL A 466
ALA A 445
 None
None
None
None
TTP  A1589 (-4.8A)
 1.02A 5n0xB-1h79A:
2.4		 5n0xB-1h79A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		5 / 12 ILE A 402
GLY A 403
HIS A 405
VAL A 466
ALA A 445
 None
None
None
None
TTP  A1589 (-4.8A)
 1.01A 5n4iA-1h79A:
0.7		 5n4iA-1h79A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 6 PRO A 287
VAL A 285
ALA A 130
PHE A 237
 None
 1.01A 5t7bA-1h79A:
2.1		 5t7bA-1h79A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 6 PRO A 287
VAL A 285
PHE A 237
THR A 198
 None
 1.09A 5t7bA-1h79A:
2.1		 5t7bA-1h79A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		3 / 3 TYR A 533
HIS A 504
PHE A 293
 None
 0.98A 6esmA-1h79A:
undetectable		 6esmA-1h79A:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 8 ASP A  35
TYR A  70
GLY A 313
SER A 398
 None
 1.10A 6giqL-1h79A:
1.2
6giqP-1h79A:
0.0
6giqT-1h79A:
0.0		 6giqL-1h79A:
22.36
6giqP-1h79A:
16.64
6giqT-1h79A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN
(Escherichia
virus
T4) 		4 / 8 HIS A 497
HIS A 405
GLU A 493
GLU A 509
 None
 1.19A 6mn4C-1h79A:
undetectable		 6mn4C-1h79A:
18.51