SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A  95
LEU A 110
ALA A 150
VAL A 107
TYR A 178
 None
 1.26A 1kt4A-1h7gA:
0.0		 1kt4A-1h7gA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 ILE A 175
ILE A   5
LEU A 205
 None
 0.55A 2prgA-1h7gA:
0.0		 2prgA-1h7gA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 SER A  75
GLY A  76
THR A  77
 None
 0.22A 3k9wA-1h7gA:
4.2		 3k9wA-1h7gA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 ASP A  78
SER A  75
ARG A 204
 None
 1.01A 3loqA-1h7gA:
0.0		 3loqA-1h7gA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		5 / 11 VAL A 142
THR A 139
GLU A 216
THR A 214
VAL A 144
 None
 1.21A 4e0fA-1h7gA:
0.0		 4e0fA-1h7gA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ILE A  91
ILE A  93
GLY A  42
ALA A  41
VAL A 107
 None
 1.00A 4nkvC-1h7gA:
undetectable		 4nkvC-1h7gA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ILE A  91
ILE A  93
GLY A  42
ALA A  41
VAL A 107
 None
 1.02A 4nkxA-1h7gA:
undetectable		 4nkxA-1h7gA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		4 / 5 ILE A 212
ARG A 179
ASP A 117
VAL A 144
 None
 1.25A 4nkxC-1h7gA:
0.0		 4nkxC-1h7gA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		4 / 6 LEU A  22
ILE A  24
LEU A 230
GLU A 231
 None
 0.76A 4w5nA-1h7gA:
2.1		 4w5nA-1h7gA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 CYH A 126
LEU A 125
ALA A 150
VAL A 142
ILE A 212
 None
 1.12A 4x1kD-1h7gA:
undetectable		 4x1kD-1h7gA:
20.22