SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1h7l SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSA
(Bacillus
subtilis) 		3 / 3 LEU A 237
TYR A 187
GLY A 190
 None
 0.61A 2ocuA-1h7lA:
undetectable		 2ocuA-1h7lA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA503_0
(CHORISMATE SYNTHASE)		 1h7l SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSA
(Bacillus
subtilis) 		4 / 5 GLN A 148
THR A 150
ALA A 153
ARG A 247
 None
 1.37A 2qhfA-1h7lA:
0.0		 2qhfA-1h7lA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1h7l SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSA
(Bacillus
subtilis) 		4 / 5 ASN A  82
ALA A  78
ALA A  79
ARG A  76
 None
 1.31A 3kp2B-1h7lA:
undetectable		 3kp2B-1h7lA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1h7l SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSA
(Bacillus
subtilis) 		4 / 7 HIS A 164
ILE A 123
VAL A 162
ARG A 106
 None
 1.29A 5kkzM-1h7lA:
0.0
5kkzO-1h7lA:
undetectable		 5kkzM-1h7lA:
20.82
5kkzO-1h7lA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1h7l SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSA
(Bacillus
subtilis) 		4 / 7 ARG A  59
PHE A  32
LEU A 107
SER A  23
 None
 1.16A 5uxcA-1h7lA:
0.0		 5uxcA-1h7lA:
22.08