SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h7y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)
1h7y TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN

(Schizosaccharomy
ces
pombe)
3 / 3 ASP A 129
VAL A 142
PRO A 138
None
0.78A 2avvA-1h7yA:
0.0
2avvA-1h7yA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)
1h7y TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 6 PHE A 117
ILE A 121
TYR A  84
PHE A 159
None
1.47A 4o7gB-1h7yA:
0.1
4o7gB-1h7yA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)
1h7y TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN

(Schizosaccharomy
ces
pombe)
6 / 12 GLY A  10
TYR A   4
ILE A 132
ASP A   6
ALA A 140
ASP A 137
None
1.48A 5kvaA-1h7yA:
undetectable
5kvaA-1h7yA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)
1h7y TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN

(Schizosaccharomy
ces
pombe)
6 / 12 GLY A  10
TYR A  28
ILE A 132
ASP A   6
ALA A 140
ASP A 137
None
1.45A 5kvaA-1h7yA:
undetectable
5kvaA-1h7yA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)
1h7y TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN

(Schizosaccharomy
ces
pombe)
6 / 12 GLY A  10
TYR A   4
ILE A 132
ASP A   6
ALA A 140
ASP A 137
None
1.44A 5kvaB-1h7yA:
undetectable
5kvaB-1h7yA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)
1h7y TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN

(Schizosaccharomy
ces
pombe)
6 / 12 GLY A  10
TYR A  28
ILE A 132
ASP A   6
ALA A 140
ASP A 137
None
1.45A 5kvaB-1h7yA:
undetectable
5kvaB-1h7yA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)
1h7y TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN

(Schizosaccharomy
ces
pombe)
5 / 10 VAL A  27
ILE A 157
GLY A 116
ALA A 114
PHE A 117
None
1.09A 5mxbA-1h7yA:
undetectable
5mxbA-1h7yA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)
1h7y TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 4 ARG A  98
ILE A  95
TYR A  91
ILE A   8
None
1.34A 5odhG-1h7yA:
undetectable
5odhG-1h7yA:
14.77