SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		3 / 3 VAL A 269
VAL A 271
TRP A 290
 None
 0.95A 1av2A-1h7zA:
undetectable
1av2B-1h7zA:
undetectable		 1av2A-1h7zA:
7.63
1av2B-1h7zA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		5 / 11 GLY A 201
THR A 200
HIS A 202
LEU A 216
GLY A 228
 None
 1.18A 2fn1A-1h7zA:
undetectable		 2fn1A-1h7zA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		3 / 3 ASN A 142
ALA A 141
LYS A 155
 None
 0.91A 3runA-1h7zA:
0.0		 3runA-1h7zA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		3 / 3 ASN A 192
LEU A 305
PHE A 288
 None
 0.51A 4dajB-1h7zA:
undetectable		 4dajB-1h7zA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		5 / 12 VAL A 271
PHE A 312
SER A 313
LEU A 160
VAL A 161
 None
 1.21A 4eckA-1h7zA:
undetectable		 4eckA-1h7zA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		6 / 12 MET A 230
ILE A 203
GLY A 136
LEU A 158
LEU A 210
LEU A 195
 None
 1.40A 4o1zA-1h7zA:
0.0		 4o1zA-1h7zA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		3 / 3 TRP A 290
ILE A 145
SER A 154
 None
 0.97A 5gqbA-1h7zA:
undetectable		 5gqbA-1h7zA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		5 / 12 LEU A 173
MET A 286
LEU A 210
ILE A 159
LEU A 214
 None
 1.02A 5toaA-1h7zA:
undetectable		 5toaA-1h7zA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		5 / 12 VAL A 239
SER A 190
SER A 291
ASN A 192
TYR A 250
 SO4  A1320 ( 4.7A)
None
None
None
None
 1.36A 6h7lA-1h7zA:
undetectable		 6h7lA-1h7zA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		5 / 12 VAL A 239
SER A 190
SER A 291
ASN A 192
TYR A 250
 SO4  A1320 ( 4.7A)
None
None
None
None
 1.35A 6h7lB-1h7zA:
undetectable		 6h7lB-1h7zA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1h7z ADENOVIRUS FIBRE
PROTEIN
(Human
mastadenovirus
B) 		4 / 7 ARG A 227
TYR A 284
GLU A 317
ASP A 318
 None
 1.19A 6mn5B-1h7zA:
undetectable		 6mn5B-1h7zA:
20.21