SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h81'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 THR A 428
GLY A  11
ALA A  20
ILE A  33
None
FAD  A 579 (-3.1A)
None
None
0.79A 1c9sI-1h81A:
undetectable
1c9sJ-1h81A:
undetectable
1c9sI-1h81A:
9.76
1c9sJ-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 GLY A  11
ALA A  20
ILE A  33
THR A 428
FAD  A 579 (-3.1A)
None
None
None
0.80A 1c9sU-1h81A:
undetectable
1c9sV-1h81A:
undetectable
1c9sU-1h81A:
9.76
1c9sV-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 7 GLY A  11
ALA A  20
ILE A  33
THR A 428
FAD  A 579 (-3.1A)
None
None
None
0.80A 1gtnA-1h81A:
undetectable
1gtnK-1h81A:
undetectable
1gtnA-1h81A:
9.76
1gtnK-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 THR A 428
GLY A  11
ALA A  20
ILE A  33
None
FAD  A 579 (-3.1A)
None
None
0.81A 1gtnA-1h81A:
undetectable
1gtnB-1h81A:
undetectable
1gtnA-1h81A:
9.76
1gtnB-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 THR A 428
GLY A  11
ALA A  20
ILE A  33
None
FAD  A 579 (-3.1A)
None
None
0.80A 1gtnE-1h81A:
undetectable
1gtnF-1h81A:
undetectable
1gtnE-1h81A:
9.76
1gtnF-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 11 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.10A 1gtnM-1h81A:
undetectable
1gtnN-1h81A:
undetectable
1gtnM-1h81A:
9.76
1gtnN-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 VAL A 331
TYR A 165
GLY A 330
TYR A 298
None
None
None
FAD  A 579 (-4.4A)
0.84A 1jlbA-1h81A:
0.0
1jlbA-1h81A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 7 VAL A 331
TYR A 165
GLY A 330
TYR A 298
None
None
None
FAD  A 579 (-4.4A)
1.00A 1lweA-1h81A:
0.0
1lweA-1h81A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
3 / 3 PHE A 305
TRP A 310
GLU A 312
None
0.75A 1mogA-1h81A:
0.0
1mogA-1h81A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
3 / 3 PHE A 309
TRP A 310
GLU A 312
None
1.15A 1mogA-1h81A:
0.0
1mogA-1h81A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 12 ALA A 259
SER A 258
ALA A 458
ASP A  30
ILE A  28
None
1.21A 1nt2A-1h81A:
2.1
1nt2A-1h81A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 VAL A 331
TYR A 165
GLY A 330
TYR A 298
None
None
None
FAD  A 579 (-4.4A)
0.81A 1s1xA-1h81A:
0.0
1s1xA-1h81A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUF_B_AZ1B503_1
(DIAMINOPIMELATE
DECARBOXYLASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 6 GLU A  35
SER A 265
ARG A  43
TYR A 399
FAD  A 579 (-2.7A)
FAD  A 579 (-4.1A)
FAD  A 579 (-3.6A)
FAD  A 579 (-4.3A)
0.95A 1tufA-1h81A:
undetectable
1tufB-1h81A:
undetectable
1tufA-1h81A:
20.89
1tufB-1h81A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 GLY A  11
ALA A  20
ILE A  33
THR A 428
FAD  A 579 (-3.1A)
None
None
None
0.78A 1utdB-1h81A:
undetectable
1utdC-1h81A:
undetectable
1utdB-1h81A:
9.76
1utdC-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 GLY A  11
ALA A  20
ILE A  33
THR A 428
FAD  A 579 (-3.1A)
None
None
None
0.77A 1utdF-1h81A:
undetectable
1utdG-1h81A:
undetectable
1utdF-1h81A:
9.76
1utdG-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 GLY A  11
ALA A  20
ILE A  33
THR A 428
FAD  A 579 (-3.1A)
None
None
None
0.78A 1utdI-1h81A:
undetectable
1utdJ-1h81A:
undetectable
1utdI-1h81A:
9.76
1utdJ-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 GLY A  11
ALA A  20
ILE A  33
THR A 428
FAD  A 579 (-3.1A)
None
None
None
0.76A 1utdJ-1h81A:
undetectable
1utdK-1h81A:
undetectable
1utdJ-1h81A:
9.76
1utdK-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.10A 1utdT-1h81A:
0.0
1utdU-1h81A:
0.0
1utdT-1h81A:
9.76
1utdU-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
3 / 3 ASP A 195
GLU A 317
TYR A 165
None
0.75A 1wsvA-1h81A:
0.0
1wsvA-1h81A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOW_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 7 PHE A 318
GLU A 317
GLN A 338
TRP A  60
None
1.29A 2aowA-1h81A:
0.7
2aowA-1h81A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 12 THR A 432
GLY A 429
GLY A 442
VAL A  10
ILE A  33
None
FAD  A 579 (-3.1A)
None
FAD  A 579 (-4.6A)
None
1.17A 2b25B-1h81A:
undetectable
2b25B-1h81A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 11 ILE A  33
GLY A  42
HIS A  39
LEU A 233
GLY A  11
None
FAD  A 579 (-3.2A)
None
None
FAD  A 579 (-3.1A)
1.42A 2fn1A-1h81A:
undetectable
2fn1A-1h81A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFF_A_QPSA600_1
(BETA-AMYLASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 12 ALA A  36
GLU A  35
TYR A 399
TRP A 393
GLY A  41
FAD  A 579 (-3.5A)
FAD  A 579 (-2.7A)
FAD  A 579 (-4.3A)
FAD  A 579 ( 3.8A)
None
1.32A 2xffA-1h81A:
0.0
2xffA-1h81A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 6 LEU A 233
ILE A  40
ILE A 448
LEU A  23
None
0.88A 2xkwB-1h81A:
0.0
2xkwB-1h81A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 12 LEU A 212
LEU A 445
ASN A  70
ILE A 448
ALA A 451
None
1.07A 3a50D-1h81A:
undetectable
3a50D-1h81A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 12 VAL A   9
ILE A  33
GLU A  35
ALA A 443
SER A 446
None
None
FAD  A 579 (-2.7A)
FAD  A 579 (-3.4A)
None
1.31A 3apwA-1h81A:
undetectable
3apwA-1h81A:
19.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KU9_A_SPMA700_1
(POLYAMINE OXIDASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
9 / 9 TRP A  60
GLU A  62
PHE A  89
TYR A 169
GLU A 170
PHE A 189
TYR A 298
PHE A 403
TYR A 439
None
FAD  A 579 (-4.4A)
None
None
None
None
FAD  A 579 (-4.4A)
FAD  A 579 (-4.7A)
FAD  A 579 (-4.8A)
0.33A 3ku9A-1h81A:
24.2
3ku9A-1h81A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KU9_A_SPMA700_1
(POLYAMINE OXIDASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 9 TRP A  60
PHE A 318
TYR A 169
TYR A 298
PHE A 403
None
None
None
FAD  A 579 (-4.4A)
FAD  A 579 (-4.7A)
1.30A 3ku9A-1h81A:
24.2
3ku9A-1h81A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
7 / 7 GLU A  62
TYR A 165
TYR A 169
GLU A 170
TYR A 298
PHE A 403
TYR A 439
FAD  A 579 (-4.4A)
None
None
None
FAD  A 579 (-4.4A)
FAD  A 579 (-4.7A)
FAD  A 579 (-4.8A)
0.28A 3ku9B-1h81A:
62.7
3ku9B-1h81A:
99.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 9 ALA A 451
VAL A   7
GLY A  16
ILE A  17
THR A  29
None
1.35A 3spkA-1h81A:
undetectable
3spkA-1h81A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)
1h81 POLYAMINE OXIDASE
(Zea
mays)
3 / 3 TYR A 399
GLU A  55
TYR A 205
FAD  A 579 (-4.3A)
None
None
0.79A 3ug8A-1h81A:
0.0
3ug8A-1h81A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 12 ALA A  19
ALA A  20
LEU A  31
ALA A 451
VAL A 237
None
None
None
None
FAD  A 579 (-3.7A)
1.22A 3uvvB-1h81A:
undetectable
3uvvB-1h81A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 5 LEU A 217
ILE A  33
LEU A  32
ARG A 230
None
0.88A 4mghA-1h81A:
0.0
4mghA-1h81A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 ARG A 356
PRO A 174
VAL A 177
GLY A 327
None
0.93A 4mk4A-1h81A:
undetectable
4mk4A-1h81A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 6 ARG A   6
ASP A  30
LEU A  34
SER A 255
None
1.06A 4ot2A-1h81A:
undetectable
4ot2A-1h81A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 12 GLY A  42
GLY A  41
GLY A  11
ALA A  12
ILE A 276
FAD  A 579 (-3.2A)
None
FAD  A 579 (-3.1A)
None
None
1.03A 4rtmA-1h81A:
2.0
4rtmA-1h81A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 TYR A 298
THR A 402
TRP A  60
PHE A 318
FAD  A 579 (-4.4A)
FAD  A 579 (-4.0A)
None
None
1.42A 4tzcB-1h81A:
undetectable
4tzcD-1h81A:
0.0
4tzcB-1h81A:
16.15
4tzcD-1h81A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.08A 5eeuO-1h81A:
0.0
5eeuP-1h81A:
0.0
5eeuO-1h81A:
9.76
5eeuP-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.09A 5eeuQ-1h81A:
0.0
5eeuR-1h81A:
0.0
5eeuQ-1h81A:
9.76
5eeuR-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.09A 5eevO-1h81A:
0.0
5eevP-1h81A:
0.0
5eevO-1h81A:
9.76
5eevP-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.09A 5eevQ-1h81A:
0.0
5eevR-1h81A:
0.0
5eevQ-1h81A:
9.76
5eevR-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.08A 5eewO-1h81A:
0.0
5eewP-1h81A:
0.0
5eewO-1h81A:
9.76
5eewP-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.09A 5eewQ-1h81A:
0.0
5eewR-1h81A:
0.0
5eewQ-1h81A:
9.76
5eewR-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.08A 5eexO-1h81A:
0.0
5eexP-1h81A:
0.0
5eexO-1h81A:
9.76
5eexP-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.09A 5eeyO-1h81A:
0.0
5eeyP-1h81A:
0.0
5eeyO-1h81A:
9.76
5eeyP-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.09A 5eezO-1h81A:
0.0
5eezP-1h81A:
0.0
5eezO-1h81A:
9.76
5eezP-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.08A 5ef0O-1h81A:
0.0
5ef0P-1h81A:
0.0
5ef0O-1h81A:
9.76
5ef0P-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.09A 5ef1O-1h81A:
0.0
5ef1P-1h81A:
0.0
5ef1O-1h81A:
9.76
5ef1P-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.09A 5ef2O-1h81A:
0.0
5ef2P-1h81A:
0.0
5ef2O-1h81A:
9.76
5ef2P-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 10 GLY A  11
ALA A  20
ILE A  33
THR A 428
ALA A  19
FAD  A 579 (-3.1A)
None
None
None
None
1.09A 5ef3O-1h81A:
0.0
5ef3P-1h81A:
0.0
5ef3O-1h81A:
9.76
5ef3P-1h81A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 12 ARG A  22
GLY A 447
GLY A 429
GLU A  35
LEU A 231
None
None
FAD  A 579 (-3.1A)
FAD  A 579 (-2.7A)
None
1.21A 5ul4A-1h81A:
undetectable
5ul4A-1h81A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 LEU A  82
TYR A 205
VAL A 208
ILE A  72
None
0.99A 5v0vA-1h81A:
undetectable
5v0vA-1h81A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 8 GLY A 214
ARG A 230
GLN A 232
ASP A 228
None
0.76A 5vlmB-1h81A:
undetectable
5vlmB-1h81A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 11 VAL A 270
GLY A 269
ASP A 396
SER A 273
LEU A 275
FAD  A 579 ( 4.9A)
None
None
None
FAD  A 579 (-4.5A)
1.23A 5x6yC-1h81A:
undetectable
5x6yC-1h81A:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
3 / 3 ASP A 416
ARG A 412
ASP A 449
None
0.80A 5zvgA-1h81A:
2.1
5zvgA-1h81A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
3 / 3 ASP A 416
ARG A 412
ASP A 449
None
0.86A 5zvgB-1h81A:
2.1
5zvgB-1h81A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)
1h81 POLYAMINE OXIDASE
(Zea
mays)
5 / 12 TYR A 329
ILE A 301
TYR A 328
LEU A 303
ALA A 367
None
1.40A 5zwrB-1h81A:
0.0
5zwrB-1h81A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)
1h81 POLYAMINE OXIDASE
(Zea
mays)
4 / 7 ILE A 357
GLU A 363
VAL A 390
TRP A 394
None
1.10A 6j20A-1h81A:
0.0
6j20A-1h81A:
21.13