SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h8u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EIZ_A_SAMA301_0 (FTSJ)	1h8u	EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1 (Homo sapiens)	5 / 12	ALA A 16 GLY A 56 TRP A 53 PHE A 67 ARG A 66	None	0.93A	1eizA-1h8uA: undetectable	1eizA-1h8uA: 19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EJ0_A_SAMA301_0 (FTSJ)	1h8u	EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1 (Homo sapiens)	5 / 12	ALA A 16 GLY A 56 TRP A 53 PHE A 67 ARG A 66	None	0.86A	1ej0A-1h8uA: undetectable	1ej0A-1h8uA: 19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M6E_X_SALX2000_1 (S-ADENOSYL-L-METHION INE:SALICYLIC ACID CARBOXYL METHYLTRANSFERASE)	1h8u	EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1 (Homo sapiens)	4 / 7	GLN A 84 TRP A 102 TRP A 75 VAL A 93	None	1.06A	1m6eX-1h8uA: 0.0	1m6eX-1h8uA: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TDN_A_LEUA487_0 (L-AMINO ACID OXIDASE)	1h8u	EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1 (Homo sapiens)	4 / 7	ASN A 35 PHE A 77 ILE A 40 TRP A 102	None GOL A1123 (-4.2A) None None	1.42A	1tdnA-1h8uA: undetectable	1tdnA-1h8uA: 15.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EIZ_A_SAMA301_0","FTSJ","1h8u","EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1","Homo sapiens",5,"ALA A  16;GLY A  56;TRP A  53;PHE A  67;ARG A  66","None","0.93A","1eizA-1h8uA:undetectable","1eizA-1h8uA:19.89"],["1EJ0_A_SAMA301_0","FTSJ","1h8u","EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1","Homo sapiens",5,"ALA A  16;GLY A  56;TRP A  53;PHE A  67;ARG A  66","None","0.86A","1ej0A-1h8uA:undetectable","1ej0A-1h8uA:19.89"],["1M6E_X_SALX2000_1","S-ADENOSYL-L-METHIONINE:SALICYLIC ACID CARBOXYL METHYLTRANSFERASE","1h8u","EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1","Homo sapiens",4,"GLN A  84;TRP A 102;TRP A  75;VAL A  93","None","1.06A","1m6eX-1h8uA:0.0","1m6eX-1h8uA:16.16"],["1TDN_A_LEUA487_0","L-AMINO ACID OXIDASE","1h8u","EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1","Homo sapiens",4,"ASN A  35;PHE A  77;ILE A  40;TRP A 102","None;GOL A1123 (-4.2A);None;None","1.42A","1tdnA-1h8uA:undetectable","1tdnA-1h8uA:15.74"]]