SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1h9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)
1h9h TRYPSIN
(Sus
scrofa)
8 / 8 HIS E  57
ASP E 189
SER E 190
GLN E 192
SER E 195
VAL E 213
GLY E 216
GLY E 226
None
0.48A 1aq7A-1h9hE:
43.5
1aq7A-1h9hE:
82.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)
1h9h TRYPSIN
(Sus
scrofa)
6 / 9 ASP E 189
SER E 195
VAL E 213
TRP E 215
GLY E 216
GLY E 226
None
0.43A 1bcuH-1h9hE:
18.4
1bcuH-1h9hE:
38.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DWC_H_MITH1_1
(ALPHA-THROMBIN
(LARGE SUBUNIT))
1h9h TRYPSIN
(Sus
scrofa)
5 / 9 HIS E  57
ASP E 189
SER E 195
TRP E 215
GLY E 226
None
0.51A 1dwcH-1h9hE:
33.7
1dwcH-1h9hE:
38.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)
1h9h TRYPSIN
(Sus
scrofa)
5 / 9 LEU E 105
ILE E 106
LEU E 209
VAL E  31
GLY E  43
None
1.25A 1e7aB-1h9hE:
undetectable
1e7aB-1h9hE:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)
1h9h TRYPSIN
(Sus
scrofa)
6 / 9 VAL E  52
LEU E  67
ILE E  63
ALA E  85
SER E 109
LEU E 108
None
1.24A 1eqgA-1h9hE:
undetectable
1eqgA-1h9hE:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)
1h9h TRYPSIN
(Sus
scrofa)
6 / 11 VAL E  52
LEU E  67
ILE E  63
ALA E  85
SER E 109
LEU E 108
None
1.24A 1eqgB-1h9hE:
undetectable
1eqgB-1h9hE:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)
1h9h TRYPSIN
(Sus
scrofa)
6 / 12 VAL E  52
LEU E  67
ILE E  63
ALA E  85
SER E 109
LEU E 108
None
1.19A 1eqhA-1h9hE:
0.0
1eqhA-1h9hE:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)
1h9h TRYPSIN
(Sus
scrofa)
6 / 12 VAL E  52
LEU E  67
ILE E  63
ALA E  85
SER E 109
LEU E 108
None
1.18A 1eqhB-1h9hE:
0.0
1eqhB-1h9hE:
17.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)
1h9h TRYPSIN
(Sus
scrofa)
8 / 12 HIS E  57
LEU E  99
ASP E 189
SER E 195
VAL E 213
TRP E 215
GLY E 216
GLY E 226
None
0.59A 1etrH-1h9hE:
33.8
1etrH-1h9hE:
38.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1h9h TRYPSIN
(Sus
scrofa)
6 / 8 ASP E 189
SER E 190
SER E 195
VAL E 213
GLY E 216
GLY E 226
None
0.39A 1f5lA-1h9hE:
11.7
1f5lA-1h9hE:
37.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
1h9h TRYPSIN
(Sus
scrofa)
5 / 10 SER E 195
SER E 214
ILE E 212
GLY E 211
GLY E 226
None
1.27A 1mehA-1h9hE:
undetectable
1mehA-1h9hE:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 ILE E 242
ILE E  47
VAL E 121
ILE E 212
ILE E 238
None
1.33A 1r5lA-1h9hE:
undetectable
1r5lA-1h9hE:
20.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)
1h9h TRYPSIN
(Sus
scrofa)
6 / 6 ASP E 189
SER E 190
SER E 195
VAL E 213
GLY E 216
GLY E 226
None
0.28A 1tnlA-1h9hE:
43.0
1tnlA-1h9hE:
82.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
1h9h TRYPSIN
(Sus
scrofa)
4 / 5 LEU E 155
ILE E  73
SER E  32
GLY E  43
None
0.94A 2otfA-1h9hE:
undetectable
2otfA-1h9hE:
17.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)
1h9h TRYPSIN
(Sus
scrofa)
6 / 6 ASP E 189
SER E 190
SER E 195
VAL E 213
GLY E 216
GLY E 226
None
0.25A 2otvA-1h9hE:
43.0
2otvA-1h9hE:
82.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))
1h9h TRYPSIN
(Sus
scrofa)
7 / 12 ASP E 189
SER E 195
VAL E 213
TRP E 215
GLY E 216
GLY E 226
TYR E 228
None
0.34A 2p16A-1h9hE:
36.0
2p16A-1h9hE:
37.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)
1h9h TRYPSIN
(Sus
scrofa)
6 / 8 ASP E 189
SER E 190
SER E 195
VAL E 213
GLY E 216
GLY E 226
None
0.36A 2vinA-1h9hE:
10.8
2vinA-1h9hE:
37.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)
1h9h TRYPSIN
(Sus
scrofa)
8 / 12 ASP E 189
SER E 195
VAL E 213
TRP E 215
GLY E 216
GLY E 219
GLY E 226
TYR E 228
None
0.38A 2w26A-1h9hE:
12.7
2w26A-1h9hE:
37.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)
1h9h TRYPSIN
(Sus
scrofa)
3 / 3 SER E 127
ARG E 125
GLN E 204
None
1.02A 2xnrA-1h9hE:
undetectable
2xnrA-1h9hE:
15.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)
1h9h TRYPSIN
(Sus
scrofa)
10 / 11 HIS E  57
LEU E  99
GLN E 175
ASP E 189
SER E 190
GLN E 192
SER E 195
TRP E 215
GLY E 216
GLY E 226
None
0.47A 3gy3A-1h9hE:
43.3
3gy3A-1h9hE:
82.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 ILE E 212
VAL E 213
GLY E  44
ALA E  55
ILE E  73
None
1.01A 3mb5A-1h9hE:
undetectable
3mb5A-1h9hE:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 LYS E  16
GLY E 197
ILE E 212
ALA E  55
ASP E 194
None
1.02A 3nvkI-1h9hE:
undetectable
3nvkI-1h9hE:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 VAL E  52
LEU E  67
ALA E  85
SER E 109
LEU E 108
None
0.99A 3pghC-1h9hE:
0.0
3pghC-1h9hE:
17.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)
1h9h TRYPSIN
(Sus
scrofa)
6 / 6 SER E 190
SER E 195
VAL E 213
TRP E 215
GLY E 216
GLY E 226
None
0.36A 3rxfA-1h9hE:
43.7
3rxfA-1h9hE:
82.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)
1h9h TRYPSIN
(Sus
scrofa)
5 / 5 ASP E 189
SER E 190
SER E 195
VAL E 213
GLY E 226
None
0.34A 3rxhA-1h9hE:
43.6
3rxhA-1h9hE:
82.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 ILE E 242
ILE E  47
VAL E 121
LEU E 209
ILE E 212
None
1.14A 3w67D-1h9hE:
undetectable
3w67D-1h9hE:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)
1h9h TRYPSIN
(Sus
scrofa)
4 / 6 THR E 144
ASN E 143
GLY E 193
ILE E  73
None
0.80A 3w9tF-1h9hE:
0.0
3w9tF-1h9hE:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)
1h9h TRYPSIN
(Sus
scrofa)
4 / 8 ILE E 212
GLY E 211
VAL E  52
GLN E  30
None
0.90A 4acbB-1h9hE:
undetectable
4acbC-1h9hE:
undetectable
4acbB-1h9hE:
18.18
4acbC-1h9hE:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)
1h9h TRYPSIN
(Sus
scrofa)
4 / 5 SER E 195
GLY E  43
THR E 229
VAL E  53
None
1.12A 4eohA-1h9hE:
undetectable
4eohA-1h9hE:
20.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1h9h TRYPSIN
(Sus
scrofa)
4 / 5 HIS E  57
GLN E 192
GLY E 193
SER E 195
None
0.83A 4fu8A-1h9hE:
34.7
4fu8A-1h9hE:
36.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HFP_B_15UB402_1
(PROTHROMBIN)
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 HIS E  57
LEU E  99
ASP E 189
GLY E 216
GLY E 226
None
0.36A 4hfpB-1h9hE:
34.1
4hfpB-1h9hE:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HFP_D_15UD402_1
(PROTHROMBIN)
1h9h TRYPSIN
(Sus
scrofa)
6 / 12 HIS E  57
LEU E  99
ASP E 189
VAL E 213
TRP E 215
GLY E 226
None
0.37A 4hfpD-1h9hE:
33.6
4hfpD-1h9hE:
38.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1h9h TRYPSIN
(Sus
scrofa)
5 / 10 VAL E  52
LEU E  67
ALA E  85
SER E 109
LEU E 108
None
0.95A 4ph9A-1h9hE:
0.0
4ph9A-1h9hE:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1h9h TRYPSIN
(Sus
scrofa)
5 / 10 VAL E  52
LEU E  67
ALA E  85
SER E 109
LEU E 108
None
0.94A 4ph9B-1h9hE:
undetectable
4ph9B-1h9hE:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 VAL E 231
GLY E  44
ILE E 103
LEU E 105
LEU E  46
None
1.04A 4qdjA-1h9hE:
undetectable
4qdjA-1h9hE:
19.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)
1h9h TRYPSIN
(Sus
scrofa)
6 / 12 HIS E  57
LEU E  99
VAL E 213
TRP E 215
GLY E 216
GLY E 226
None
0.31A 4rn6B-1h9hE:
28.1
4rn6B-1h9hE:
38.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
1h9h TRYPSIN
(Sus
scrofa)
3 / 3 TYR E 217
SER E 171
TRP E 215
None
0.84A 5n8jB-1h9hE:
0.0
5n8jB-1h9hE:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
1h9h TRYPSIN
(Sus
scrofa)
3 / 3 TYR E 217
SER E 171
TRP E 215
None
0.80A 5n8jA-1h9hE:
0.0
5n8jA-1h9hE:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
1h9h TRYPSIN
(Sus
scrofa)
3 / 3 TYR E 217
SER E 171
TRP E 215
None
0.80A 5n8jD-1h9hE:
0.0
5n8jD-1h9hE:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 GLY E 142
GLY E 196
GLY E  43
GLY E 140
PHE E  94
None
0.93A 5vimB-1h9hE:
undetectable
5vimB-1h9hE:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 GLY E 226
VAL E  53
GLY E 196
SER E 195
ILE E 212
None
1.05A 5vopA-1h9hE:
undetectable
5vopA-1h9hE:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)
1h9h TRYPSIN
(Sus
scrofa)
5 / 12 GLY E 211
VAL E 231
VAL E  53
GLN E  30
GLY E 196
None
1.16A 6gneA-1h9hE:
undetectable
6gneA-1h9hE:
18.97