SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hbz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1hbz CATALASE
(Micrococcus
luteus) 		3 / 3 GLN A  16
HIS A  49
ARG A  52
 None
 0.69A 1zlqA-1hbzA:
undetectable		 1zlqA-1hbzA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 ARG A 120
TYR A 128
TYR A 205
TYR A 219
 None
 1.02A 2ajvH-1hbzA:
undetectable
2ajvL-1hbzA:
undetectable		 2ajvH-1hbzA:
17.43
2ajvL-1hbzA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 ARG A 141
ASP A 425
ALA A 430
ASP A 426
 None
 1.24A 2e5dA-1hbzA:
0.0
2e5dB-1hbzA:
undetectable		 2e5dA-1hbzA:
22.58
2e5dB-1hbzA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 ASP A 426
ARG A 141
ASP A 425
ALA A 430
 None
 1.25A 2e5dA-1hbzA:
undetectable
2e5dB-1hbzA:
undetectable		 2e5dA-1hbzA:
22.58
2e5dB-1hbzA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 ARG A 112
ALA A 465
GLY A 477
ILE A 476
 None
 0.82A 2fxdB-1hbzA:
undetectable		 2fxdB-1hbzA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 5 VAL A 181
THR A 182
VAL A 472
TRP A 469
 None
 1.06A 2p2fA-1hbzA:
undetectable		 2p2fA-1hbzA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 ALA A 342
ALA A 346
PRO A 321
ARG A  58
 HEM  A 504 ( 3.9A)
HEM  A 504 ( 3.8A)
None
HEM  A 504 (-4.0A)
 0.95A 2ql8A-1hbzA:
undetectable
2ql8B-1hbzA:
0.0		 2ql8A-1hbzA:
13.45
2ql8B-1hbzA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 6 SER A 107
ARG A 162
PRO A 493
GLY A 494
 None
 1.41A 2y7pA-1hbzA:
0.0		 2y7pA-1hbzA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 PHE A 149
LEU A 184
VAL A 114
THR A 100
 None
 0.98A 2zaxA-1hbzA:
undetectable		 2zaxA-1hbzA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 PHE A 149
LEU A 184
VAL A 114
THR A 100
 None
 0.96A 3fwgB-1hbzA:
0.0		 3fwgB-1hbzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 PHE A 149
LEU A 184
VAL A 114
THR A 100
 None
 1.00A 3fwiA-1hbzA:
undetectable		 3fwiA-1hbzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 5 THR A 449
GLY A 491
PRO A 493
ASN A 232
 None
 1.29A 3u8qA-1hbzA:
undetectable		 3u8qA-1hbzA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1hbz CATALASE
(Micrococcus
luteus) 		5 / 12 LEU A 303
LEU A 301
ARG A 305
LYS A 308
GLN A 313
 None
 1.27A 4f4dA-1hbzA:
undetectable		 4f4dA-1hbzA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1hbz CATALASE
(Micrococcus
luteus) 		3 / 3 LEU A 190
PRO A 191
ARG A 162
 None
 0.72A 4klrB-1hbzA:
undetectable		 4klrB-1hbzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 6 GLY A 132
ASP A 129
PRO A 321
ARG A 339
 HEM  A 504 (-3.8A)
None
None
HEM  A 504 (-3.5A)
 1.08A 4lajA-1hbzA:
undetectable
4lajB-1hbzA:
undetectable		 4lajA-1hbzA:
22.03
4lajB-1hbzA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 6 GLY A 201
ASP A 129
PRO A 321
ARG A 339
 None
None
None
HEM  A 504 (-3.5A)
 0.98A 4lajA-1hbzA:
undetectable
4lajB-1hbzA:
undetectable		 4lajA-1hbzA:
22.03
4lajB-1hbzA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 PHE A  68
ILE A 314
PHE A 319
ASN A 361
 None
None
HEM  A 504 (-4.6A)
None
 1.24A 4o7gA-1hbzA:
undetectable
4o7gB-1hbzA:
undetectable		 4o7gA-1hbzA:
17.39
4o7gB-1hbzA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 6 PHE A  68
ILE A 314
PHE A 319
ASN A 361
 None
None
HEM  A 504 (-4.6A)
None
 1.23A 4o7gB-1hbzA:
undetectable		 4o7gB-1hbzA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 6 ILE A 476
ASP A 473
ARG A 435
VAL A 437
 None
 0.99A 4oltB-1hbzA:
0.0		 4oltB-1hbzA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 1hbz CATALASE
(Micrococcus
luteus) 		4 / 7 MET A 197
HIS A  61
GLY A 132
ASN A 133
 None
HEM  A 504 (-3.3A)
HEM  A 504 (-3.8A)
HEM  A 504 (-3.2A)
 1.31A 5a5zC-1hbzA:
undetectable		 5a5zC-1hbzA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 1hbz CATALASE
(Micrococcus
luteus) 		5 / 9 GLY A 499
LEU A 454
LYS A 455
ARG A 458
ASP A 460
 None
 1.28A 6c2mC-1hbzA:
0.0		 6c2mC-1hbzA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1hbz CATALASE
(Micrococcus
luteus) 		5 / 12 ASP A 113
VAL A 101
SER A 152
PHE A 139
PHE A 149
 None
 1.43A 6h7mB-1hbzA:
undetectable		 6h7mB-1hbzA:
11.13